YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma

Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination

(2017) Xin Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The interplay between DNA repair and autophagy in cancer therapy

(2015) Dan Zhang et al.   CANCER BIOLOGY & THERAPY

STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma

(2015) J. Lau et al.   CANCER RESEARCH

Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy

(2015) Byeong Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma

(2015) Kyle T. Householder et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Radiation promotes invasiveness of non-small-cell lung cancer cells through granulocyte-colony-stimulating factor

(2015) Y-H Cui et al.   ONCOGENE

A sorafenib derivative and novel SHP-1 agonist, SC-59, acts synergistically with radiotherapy in hepatocellular carcinoma cells through inhibition of STAT3

(2014) Chao-Yuan Huang et al.   CANCER LETTERS

Silencing of Survivin Using YM155 Inhibits Invasion and Suppresses Proliferation in Glioma Cells

(2014) Hua Guo et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair

(2014) Qin Qin et al.   Journal of Hematology & Oncology

Inhibition of TBK1 attenuates radiation-induced epithelial–mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1

(2014) Wen Liu et al.   LABORATORY INVESTIGATION

MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway

(2014) Hongyi Zhang et al.   STEM CELLS

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Sorafenib Enhances Radiation-Induced Apoptosis in Hepatocellular Carcinoma by Inhibiting STAT3

(2013) Chao-Yuan Huang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Pharmacokinetics, distribution and excretion of YM155 monobromide, a novel small-molecule survivin suppressant, in male and pregnant or lactating female rats

(2012) Tsuyoshi Minematsu et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1

(2012) Oscar H. Ocaña et al.   CANCER CELL

Essential role of cooperative NF-κB and Stat3 recruitment to ICAM-1 intronic consensus elements in the regulation of radiation-induced invasion and migration in glioma

(2012) D Kesanakurti et al.   ONCOGENE

Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma

(2012) Makoto Adachi et al.   ORAL ONCOLOGY

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model

(2011) Takahito Nakahara et al.   ANTI-CANCER DRUGS

Ionizing Radiation Promotes Migration and Invasion of Cancer Cells Through Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition

(2011) Yong-Chun Zhou et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

(2008) Stéphane Ansieau et al.   CANCER CELL

Radiosensitizing Effect of YM155, a Novel Small-Molecule Survivin Suppressant, in Non-Small Cell Lung Cancer Cell Lines

(2008) T. Iwasa et al.   CLINICAL CANCER RESEARCH