Review
Cell Biology
Cristina Correia, Taylor M. Weiskittel, Choong Yong Ung, Jose C. Villasboas Bisneto, Daniel D. Billadeau, Scott H. Kaufmann, Hu Li
Summary: Cancer stem cells (CSCs) play crucial roles in disease propagation and therapy resistance, relying on multiple molecular cues and cellular niche interactions. Understanding CSC biology is essential for developing more effective anticancer treatments.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Psychology, Developmental
Amy S. Weitlauf, Alexandra Miceli, Alison Vehorn, Yewande Dada, Theodora Pinnock, Joyce W. Harris, Jeffrey Hine, Zachary Warren
Summary: Despite advances in screening and awareness, Black and multiracial families face challenges in getting an autism diagnosis for their children. A survey of 400 such families in the United States revealed early developmental concerns, barriers in accessing care, and recommendations for better medical support for Black and multiracial children with autism. These findings emphasize the importance of culturally sensitive and accessible care for these families.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Psychology, Social
David S. March, Lowell Gaertner, Michael A. Olson
Summary: The study demonstrates that White Americans automatically associate Black men with physical threat, and this association is stronger than the association with negativity. This association is unique to Black men and does not extend to Asian men as a general intergroup effect.
JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY
(2021)
Article
Engineering, Environmental
Jonas Bruenjes, Michael Seidel, Thorsten Dittmar, Jutta Niggemann, Florence Schubotz
Summary: Natural oil seepages contribute a significant amount of petroleum input to marine systems, and the environmental implications and persistence of water-soluble hydrocarbons from these seeps are not well understood. This study investigated the release of oil-derived dissolved organic matter (DOM) from natural deep sea asphalt seeps, finding that aliphatic asphalt-derived DOM was readily biodegraded, while aromatic and sulfur-enriched DOM appeared to be less bioavailable and accumulated in the aqueous phase.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Chemistry, Analytical
Abhishek A. Kulkarni, Neha K. Gaikwad, Tejasvinee S. Bhat
Summary: Black phosphorus (BP) has promising applications in energy storage devices due to its narrow band gap, flexibility, high conductivity, and anisotropic structure. This review discusses the synthesis of BP-based electrodes, their properties, and their use in supercapacitors (SCs). Strategies to enhance electrochemical performance and potential for constructing low-cost, flexible, and high-performing materials for SCs are also explored. The review concludes by identifying current shortcomings and future research directions to further improve this field.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Business
Marta Frasquet, Maria-Jose Miquel-Romero, Alejandro Molla-Descals
Summary: Showrooming is a common behavior that poses challenges to store-based retailers when consumers make purchases from competing online retailers. However, showrooming can also be a loyal behavior, which has not been well studied. This study aims to provide knowledge for multichannel retailers on how to retain consumers who showroom. The results indicate that online price advantage and salesperson quality influence loyal showrooming and competitive showrooming respectively, and product category and purchase device affect the transition from showrooming intention to behavior. Several managerial implications are proposed based on these findings.
ELECTRONIC COMMERCE RESEARCH AND APPLICATIONS
(2023)
Article
Criminology & Penology
Amy Farrell, Sarah Lockwood
Summary: Hate crimes and the legal responses to them have become a major concern due to the exclusion of certain groups based on their identity. This review examines the legal framework and attempts to expand hate crime protections, recent trends in hate crime victimization, the characteristics of perpetrators and victims, and the efficacy of efforts to respond to and prevent hate crimes. It suggests that future research and policy should be more inclusive of victimization that extends beyond traditional hate crimes.
ANNUAL REVIEW OF CRIMINOLOGY
(2023)
Article
Plant Sciences
Adam Richard-Bollans, Conal Aitken, Alexandre Antonelli, Cassia Bitencourt, David Goyder, Eve Lucas, Ian Ondo, Oscar A. Perez-Escobar, Samuel Pironon, James E. Richardson, David Russell, Daniele Silvestro, Colin W. Wright, Melanie-Jayne R. Howes
Summary: Plants are a valuable source of bioactive compounds, including antiplasmodial compounds for malaria prevention and treatment. Traditional ethnobotanical knowledge has limitations in identifying antiplasmodial plants, but machine learning incorporating ethnobotanical and plant trait data shows promise in accelerating the search for new compounds. A novel dataset on antiplasmodial activity for three flowering plant families is presented, demonstrating the ability of machine learning algorithms to predict the potential of plant species. Machine learning models outperform ethnobotanical approaches in precision, with the Support Vector classifier performing the best. The results suggest a large, untapped potential in the search for new plant-derived antiplasmodial compounds.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Geosciences, Multidisciplinary
Tamas Bodai, June-Yi Lee, Sundaresan Aneesh
Summary: Teleconnections are prominent features of internal variability, which can also undergo forced changes. Assessing these changes based on single realization observational data may be biased, with neglecting low-frequency variability being reasonable but omitting detrending potentially leading to larger biases. Nonlinear changes in teleconnection strength are suggested as the main irreducible source of nonergodicity.
GEOPHYSICAL RESEARCH LETTERS
(2022)
Article
Environmental Sciences
Changchun Huang, Lize Meng, Yao He, Nana Shang, Heyu Yu, Tao Huang, A-xing Zhu, Hao Yang, Kan Zhao, Ling Yao
Summary: Black carbon (BC) with high aromaticity and stability is recognized as a substantial fraction of the carbon pool in soil and sediment. In a eutrophic urban lake like Taihu Lake, BC, mainly composed of char and soot, is influenced by terrestrial inputs and fossil fuel consumption. The distribution and composition of BC and its sources, including PAHs, are key factors influencing the carbon pool in lake water.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Biochemistry & Molecular Biology
Rebekah de Nys, Raman Kumar, Jozef Gecz
Summary: The variants of PCDH19 gene have been linked to early-onset developmental epileptic encephalopathy clustering epilepsy, with alterations in steroidogenesis and NHR-related gene expression in affected individuals. The effectiveness of steroid-based antiepileptic drugs in treating this disorder remains uncertain, calling for further research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Mengdi Song, Xin Li, Suding Yang, Xuena Yu, Songxiu Zhou, Yiming Yang, Shiyi Chen, Huabin Dong, Keren Liao, Qi Chen, Keding Lu, Ningning Zhang, Junji Cao, Limin Zeng, Yuanhang Zhang
Summary: VOCs in Xi'an primarily come from vehicle exhaust and industrial emissions, while aging sources contribute significantly in rural areas. The study indicates a strong local VOC source in Xi'an, with alkenes, aromatics, and oxygenated VOCs playing a dominant role in secondary transformation.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2021)
Review
Medicine, General & Internal
Esther M. F. van Sluijs, Ulf Ekelund, Inacio Crochemore-Silva, Regina Guthold, Amy Ha, David Lubans, Adewale L. Oyeyemi, Ding Ding, Peter T. Katzmarzyk
Summary: Young people aged 10-24 years make up a significant portion of the global population, but research on adolescent physical activity is lacking. Majority of adolescents are insufficiently active, with many engaging in over 2 hours of recreational screen time daily.
Review
Endocrinology & Metabolism
Christopher D. Wiley, Judith Campisi
Summary: Cellular senescence involves a permanent proliferative arrest and the release of biologically active molecules known as SASP. Studies show that senescence and SASP are sensitive to metabolic states, potentially driving phenotypes associated with metabolic dysfunction. Effective interventions may disrupt the feedback loop in which cellular senescence promotes metabolic diseases.
Article
Business
Arne De Keyser, Yakov Bart, Xian Gu, Stephanie Q. Liu, Stacey G. Robinson, P. K. Kannan
Summary: This article explores the principles, opportunities, challenges, and future research directions of biometric data. Biometric data has potential in the business field, but also comes with issues such as privacy and security.
JOURNAL OF BUSINESS RESEARCH
(2021)
Review
Pediatrics
Numa P. Perez, Hira Ahmad, Hanna Alemayehu, Erika A. Newman, Cynthia Reyes-Ferral
Summary: This article discusses the impact of race and socioeconomic status on healthcare access, quality, and outcomes for pediatric patients. It highlights the importance of social determinants of health and introduces the five domains of social determinants of health that affect children. The article also provides strategies for identifying and addressing needs in these domains from the perspective of healthcare providers, hospitals, and health systems, with the goal of improving surgical outcomes and the well-being of all children.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Article
Surgery
Tingsong Yang, Zhi Ven Fong, Linda Pak, Shengnan J. Wang, Jia Wei, Jiping Wang
Summary: The current AJCC T stage classification for gastric neuroendocrine tumors has been shown to have poor prognostic discriminability. A modified T-stage classification was proposed in this study, demonstrating significantly improved stratification for patients. Validation of the modified T-stage classification was performed using separate population data registries, showing consistent results.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Surgery
Thomas M. Ward, Daniel A. Hashimoto, Yutong Ban, Guy Rosman, Ozanan R. Meireles
Summary: The study found that an AI model can accurately identify the degree of gallbladder inflammation, which has an impact on the intra-operative course. The automated assessment system can be used for optimizing the workflow in the operating room and providing targeted feedback to surgeons and residents, accelerating the acquisition of operative skills.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Douglas J. Cassidy, Taylor M. Coe, Kristen M. Jogerst, Sophia K. McKinley, Naomi M. Sell, Michael Sampson, Yoon Soo Park, Emil Petrusa, Robert N. Goldstone, Daniel A. Hashimoto, Denise W. Gee
Summary: This study evaluated the impact of virtual reality endoscopy training on live porcine endoscopy performance and compared the effectiveness of proficiency-based and repetition-based training curricula. The results showed that virtual reality training improved both upper and lower endoscopy performance and manual skills. The type of training curriculum did not significantly affect exam performance, but proficiency-based training was more time-effective and provided a structured approach to preparation.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Nikhil Panda, Numa Perez, Elena Tsangaris, Maria Edelen, Andrea Pusic, Feibi Zheng, Alex B. Haynes
Summary: mHealth digital health tools have great potential in improving patient-centered surgical care, but their widespread implementation faces challenges in terms of data value, clinical feasibility, and integration into healthcare workflows.
JOURNAL OF SURGICAL RESEARCH
(2022)
Letter
Oncology
Zhi Ven Fong, Lara N. Traeger, David C. Chang
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Surgery
Lydia R. Maurer, Chukwuma N. Eruchalu, Apostolos Gaitanidis, Majed El Hechi, Benjamin G. Allar, Amina Rahimi, Ali Salim, George C. Velmahos, Numa P. Perez, Claire de Crescenzo, April E. Mendoza, Tanujit Dey, Haytham M. Kaafarani, Gezzer Ortega
Summary: Patients with limited English proficiency (LEP) have worse outcomes after surgery compared to those with English proficiency. This study evaluated the association of LEP with outcomes for trauma patients and found that trauma patients with LEP had similar length of stay and 30-day readmission rate, but were less likely to be discharged to post-acute care facilities.
AMERICAN JOURNAL OF SURGERY
(2023)
Article
Pediatrics
Numa P. Perez, Emily E. Witt, Peter T. Masiakos, Ilan Layman, Joseph E. Tonna, Gezzer Ortega, Faisal G. Qureshi
Summary: This study analyzed the neurologic complications of neonatal Veno-Venous ECMO using VVDL + V and VVDL cannulation. The results showed that compared to VVDL, patients with VVDL + V had higher mortality rates, higher conversion rates to VA ECMO, and higher rates of mechanical and hemorrhagic complications, but there were no differences in neurologic outcomes, pump flows, or mortality.
JOURNAL OF PEDIATRIC SURGERY
(2023)
Article
Oncology
Zhi Ven Fong, Jonathan Teinor, Theresa P. Yeo, Dee Rinaldi, Jonathan B. Greer, Harish Lavu, Motaz Qadan, Fabian M. Johnston, Cristina R. Ferrone, David C. Chang, Charles J. Yeo, Christopher L. Wolfgang, Andrew L. Warshaw, Keith D. Lillemoe, Carlos Fernandez-Del Castillo, Matthew J. Weiss, Jennifer L. Wolff, Albert W. Wu
Summary: Working caregivers of pancreatic and periampullary cancer patients experience negative impacts on work and productivity, and caregiving-related financial and emotional difficulties may be amplified.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Review
Chemistry, Analytical
Swathikan Chidambaram, Yathukulan Maheswaran, Kian Patel, Viknesh Sounderajah, Daniel A. Hashimoto, Kenneth Patrick Seastedt, Alison H. McGregor, Sheraz R. Markar, Ara Darzi
Summary: Wearable technologies are small electronic and mobile devices that can be worn on the body and have sensors to collect data, which can be processed and analyzed by artificial intelligence systems. The use of AI in sports such as basketball, baseball, and motor racing has shown improvements in athletic performance. However, there are challenges in adopting AI technologies in sports medicine.
Review
Health Care Sciences & Services
Pietro Mascagni, Deepak Alapatt, Luca Sestini, Maria S. Altieri, Amin Madani, Yusuke Watanabe, Adnan Alseidi, Jay A. Redan, Sergio Alfieri, Guido Costamagna, Ivo Boskoski, Nicolas Padoy, Daniel A. Hashimoto
Summary: Computer vision, the application of algorithms to analyze and interpret visual data, has become a critical technology in studying the intraoperative phase of care, supporting safer surgery, and expanding access to surgical care. However, there are currently no widely used computer vision tools for diagnostic or therapeutic applications in surgery.
NPJ DIGITAL MEDICINE
(2022)
Editorial Material
Oncology
Avril K. Coley, Zhi Ven Fong
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Zhi Ven Fong, Jonathan Teinor, Theresa P. Yeo, Dee Rinaldi, Jonathan B. Greer, Harish Lavu, Motaz Qadan, Fabian M. Johnston, Cristina R. Ferrone, David C. Chang, Charles J. Yeo, Christopher L. Wolfgang, Andrew L. Warshaw, Keith D. Lillemoe, Carlos Fernandez-del Castillo, Jennifer L. Wolff, Albert W. Wu, Matthew J. Weiss
Summary: People with pancreatic and periampullary cancers often rely on family and unpaid caregivers for assistance after surgery, but little is known about the nature and difficulty of the assistance they provide. This study aimed to assess the frequency and difficulty of specific assistance caregivers provide and identify potential interventions to alleviate their caregiving demands.
JCO ONCOLOGY PRACTICE
(2023)
Review
Gastroenterology & Hepatology
Zhi Ven Fong, Yasmin G. G. Hernandez-Barco, Carlos Fernandez-del Castillo
Summary: Intraductal papillary mucinous neoplasms (IPMNs) are commonly diagnosed and range from benign to malignant lesions. Current prediction of high-grade dysplasia and invasive cancer relies on clinical and radiographic features to guide treatment decisions. However, the natural history of IPMNs is not completely understood and guidelines from different societies provide conflicting recommendations, making it challenging to balance the risk of missing cancer with surveillance and surgical resection morbidity. This review aims to reconcile guideline differences, provide a clinical framework for IPMN management, and highlight advances to minimize missed cancers and unnecessary operations.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Surgery
Amin Madani, Babak Namazi, Maria S. Altieri, Daniel A. Hashimoto, Angela Maria Rivera, Philip H. Pucher, Allison Navarrete-Welton, Ganesh Sankaranarayanan, L. Michael Brunt, Allan Okrainec, Adnan Alseidi
Summary: This study developed and evaluated artificial intelligence models that can identify safe and dangerous zones, as well as anatomical landmarks, during laparoscopic cholecystectomy (LC). The models showed promising results in accurately identifying these areas, indicating the potential for real-time guidance in surgery to minimize adverse events.