Article
Clinical Neurology
Song Li, Zhengzhi Wu, Weidong Le
Summary: In Western medicine, dementia affects cognition, mental health, and physical abilities, while Traditional Chinese Medicine explains it from the perspectives of brain dystrophy, Spleen-Kidney weakness, Blood stasis, and Phlegm stagnation. Ancient Chinese physicians believed that dementia manifests not only as cognitive symptoms but also as psychiatric disorders and sleep disturbance, offering various treatment methods.
ALZHEIMERS & DEMENTIA
(2021)
Review
Pharmacology & Pharmacy
Lei Li, Man Wang, Jikuai Chen, Juelin Chen, Yawei Wang, Minghao Zhao, Qing Song, Shuogui Xu
Summary: As global warming continues, heat waves are becoming more frequent and intense, leading to an increase in the incidence of heat stroke. Heat stroke is associated with significant morbidity and mortality, and further research is urgently needed to address this issue. Traditional Chinese medicine offers potential treatment methods, including herbal therapies and external treatments, which may provide clinical benefits and research directions for heat stroke.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Biochemical Research Methods
Hanjiao He, Wenjuan Sun, Jiao Chang, Shuyuan Hu, Jing Yang, Xu Yi, Fei Yan, Yi Long
Summary: Periploca forrestii Schltr. contains cardiac glycosides that have therapeutic effects on autoimmune diseases. Immunoaffinity chromatography (IAC) was used to selectively deplete target components and identify active substances from P. forrestii extracts. The study showed that CPS exhibited immunosuppressive effects via inhibiting the T helper 1 (Th1) cell immune response.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Review
Spectroscopy
Chung-Yu Chen, Yen-Hsien Li, Zuguang Li, Maw-Rong Lee
Summary: Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications. The characterization of the phytochemical components in TCMs is important for studying their therapeutic mechanism. Chromatography combined with mass spectrometry techniques, such as gas chromatography-MS and liquid chromatography-MS, are commonly used for the analysis of trace components in TCM samples. This article also introduces a new ambient ionization MS method for rapid and high-throughput analysis of TCM components.
MASS SPECTROMETRY REVIEWS
(2022)
Article
Chemistry, Analytical
Yujia Tu, Linnan Li, Zhengtao Wang, Li Yang
Summary: Traditional Chinese medicine injections (TCMIs) are a new form of pharmaceuticals in the modernization of traditional Chinese medicines, with rapid efficacy and improved curative effects. Chemical and biological analysis methods are widely used in the quality control of TCMIs, with emerging techniques being introduced for better control.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Plant Sciences
Wei Zhuang, Shao-Li Liu, Sheng-Yan Xi, Ying-Nan Feng, Ke Wang, Teliebald Abduwali, Ping Liu, Xiao-Jiang Zhou, Lan Zhang, Xian-Zhe Dong
Summary: This article summarizes the frequently used traditional Chinese medicine decoctions and Chinese patent medicines for treating depression, reviews their clinical therapeutic effects and possible mechanisms, and highlights the importance of traditional Chinese medicine in the management of depression.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Xue Bai, Meng Zhang
Summary: Research has shown that traditional Chinese medicine has a clinical impact on vascular dementia, improving patients' cognitive function and quality of life. The pharmacological mechanisms of TCM for VD treatment include targeting the kidneys, eliminating turbidity, and promoting blood circulation, indicating promising prospects.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Chao Mo, Jie Zhao, Jingyan Liang, Huiling Wang, Yu Chen, Guodong Huang
Summary: Exosomes play a crucial role in intercellular communication, and the interaction between exosomes and traditional Chinese medicine (TCM) has beneficial effects on various diseases. TCM formulas and compounds can modulate exosomes to inhibit cell proliferation, reduce inflammation, and attenuate fibrosis. Additionally, exosomes serve as a natural delivery system for TCM compounds, and they may also be potential biomarkers for TCM syndromes.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Biology
Qi Zhang, Jianhang Zhou, Bob Zhang
Summary: This study systematically summarizes the development of computational TCM diagnosis, focusing on digital acquisition devices, collected datasets, and computational detection methods. It provides principles, applications, and current progress in computing for computational TCM diagnosis while discussing future development directions and technological trends.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Chien-Yu Ko, Jung Chao, Pei-Yu Chen, Shan-Yu Su, Tomoji Maeda, Chin-Yu Lin, Hung-Che Chiang, Shyh-Shyun Huang
Summary: The study investigated 74 skin whitening prescriptions sold in TCM pharmacies in Taiwan, revealing 90 traditional Chinese medicinal materials mainly sourced from Apiaceae and Leguminosae. Oral prescriptions were mostly warm and sweet, while external prescriptions included cold and bitter medicinal materials, with a focus on tonifying and replenishing effects. Pharmacological analysis indicated potential benefits for wound healing, inflammatory skin diseases, and anti-hyperpigmentation.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Medicine, Research & Experimental
Wang Shao-Mei, Ye Li-Fang, Wang Li-Hong
Summary: Heart failure often stems from various cardiovascular diseases, with an energy metabolism disorder of cardiomyocytes serving as a molecular basis. Current drugs like ARNi and SGLT-2 inhibitors target myocardial metabolism to treat HF. Traditional Chinese medicine, including Danshen yin and Fufang Danshen dripping pill, has gained acceptance for HF treatment, potentially serving as a complementary approach for prevention.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Integrative & Complementary Medicine
Jillian L. Capodice, Barbara M. Chubak
Summary: Traditional Chinese Medicine (TCM) is a comprehensive medical system that has been developed over thousands of years and is utilized in the treatment of COVID-19. This paper highlights the use of TCM in treating COVID-19, discussing concepts and challenges of integrating TCM into medical settings.
Review
Pharmacology & Pharmacy
Ming Lyu, Guanwei Fan, Guangxu Xiao, Taiyi Wang, Dong Xu, Jie Gao, Shaoqin Ge, Qingling Li, Yuling Ma, Han Zhang, Jigang Wang, Yuanlu Cui, Junhua Zhang, Yan Zhu, Boli Zhang
Summary: The COVID-19 pandemic poses a significant threat to global public health and safety, with the crucial role and potential mechanisms of Traditional Chinese Medicine (TCM) in combination with Western medicine highlighted and discussed. A comprehensive review of the clinical effects and potential mechanisms of TCM on COVID-19 is presented, aiming to provide reference for healthcare professionals and the public, and facilitate understanding of the true scientific value of TCM.
ACTA PHARMACEUTICA SINICA B
(2021)
Letter
Pharmacology & Pharmacy
Lisha You, Kun Liang, Rui An, Xinhong Wang
Summary: This review provides a brief overview of the global contribution of traditional Chinese medicine (TCM), as well as the underlying obstacles and limitations for its development and modernization. The laborious progression of TCM globalization is illustrated through statistics and corresponding reasons. Innovative strategies and advanced technologies are advised to facilitate and accelerate TCM's expansion into the global markets.
PHARMACOLOGICAL RESEARCH
(2022)
Letter
Pharmacology & Pharmacy
Lisha You, Kun Liang, Rui An, Xinhong Wang
Summary: This review focuses on the global contribution of traditional Chinese medicine and the obstacles faced in its development and modernization. It also presents statistics and reasons to illustrate the challenges of TCM globalization, while offering innovative strategies and advanced technologies to facilitate its expansion into global markets.
PHARMACOLOGICAL RESEARCH
(2022)