期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 83, 期 11, 页码 6133-6141出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b01000
关键词
-
资金
- Ministry of Science and Technology, Taiwan [MOST103-2113-M-002-002-MY3]
A transition-metal-free approach for the preparation of N-arylketimines has been developed from the direct reaction of aryldiazonium salts, arenes, and nitriles in a one-pot fashion with the consecutive formation of N-C and C-C bonds. This approach proceeds via an in situ generation of N-arylnitrilium intermediate, which then undergoes intermolecular arylation. This three-component strategy offers a step- and atom-efficient way to N-arylketimines from easily accessible reagents under mild reaction conditions. The characterization of stereochemistry of ketimine was achieved by X-ray crystallographic structure and theoretical calculation. Operational simplicity, shorter reaction time, excellent functional group compatibility, and scalability are the key features of this report.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据