期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 83, 期 6, 页码 3236-3244出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b00140
关键词
-
资金
- CSIR, India [01(2779/14/EMR-II]
- SERB (DST), India [YSS/2014/000877]
- IISER-Kolkata
- UGC, India
- SERB (DST) [PDF/2016/000213]
[Graphics] Herein we report a transition-metal-free synthetic protocol for heterobiaryls, one of the most important pharmacophores in the modern drug industry, employing a new multidonor phenalenyl (PLY)-based ligand. The current procedure offers a wide substrate scope (24 examples) with a low catalyst loading resulting in an excellent product yield (up to 95%). The reaction mechanism involves a single electron transfer (SET) from a phenalenyl-based radical to generate a reactive heteroaryl radical. To establish the mechanism, we have isolated the catalytically active SET initiator, characterizing by a magnetic study.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据