Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Up-regulation of Siah1 by ethanol triggers apoptosis in neural crest cells through p38 MAPK-mediated activation of p53 signaling pathway

(2016) Fuqiang Yuan et al.   ARCHIVES OF TOXICOLOGY

Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation

(2016) Liudmila Efremova et al.   ARCHIVES OF TOXICOLOGY

Neuroprotection by vitamin C against ethanol -induced neuroinflammation associated neurodegeneration in developing rat brain

(2016) Ashfaq Ahmad et al.   CNS & Neurological Disorders-Drug Targets

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

(2016) Jeffrey R. Liddell et al.   Journal of Neuroinflammation

Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK

(2016) Siew Ying Wong et al.   Journal of Neuroinflammation

Neuroprotective effect of melatonin in experimental optic neuritis in rats

(2016) Marcos L. Aranda et al.   JOURNAL OF PINEAL RESEARCH

Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway

(2016) Silvia Carloni et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium-dependent translocation of Drp1 to the mitochondria

(2016) Shangcheng Xu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviolet rad

(2016) Konrad Kleszczyński et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

(2015) Hongkwan Cho et al.   Journal of Neuroinflammation

Melatonin prevents neural tube defects in the offspring of diabetic pregnancy

(2015) Shangming Liu et al.   JOURNAL OF PINEAL RESEARCH

Immunoregulatory actions of melatonin and zinc during chronicTrypanosoma cruziinfection

(2015) Vânia Brazão et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases

(2014) Jamie L. Lim et al.   ARCHIVES OF TOXICOLOGY

Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-KB/JNK signaling pathway in aging mouse model

(2014) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Paternal ethanol exposure and behavioral abnormities in offspring: Associated alterations in imprinted gene methylation

(2014) Fei Liang et al.   NEUROPHARMACOLOGY

Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats

(2014) C.-S. Wong et al.   NEUROSCIENCE

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

(2013) Esther Parada et al.   JOURNAL OF PINEAL RESEARCH

Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

(2013) Ayesha Maqbool et al.   Molecular Neurodegeneration

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin

(2012) Tobias W. Fischer et al.   JOURNAL OF PINEAL RESEARCH

Attenuation of NF-κβ mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol

(2012) Vinod Tiwari et al.   NEUROCHEMISTRY INTERNATIONAL

Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades

(2010) Geeta Negi et al.   JOURNAL OF PINEAL RESEARCH

Update on the use of melatonin in pediatrics

(2010) Eloisa Gitto et al.   JOURNAL OF PINEAL RESEARCH

Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy

(2009) Hans G. Richter et al.   JOURNAL OF PINEAL RESEARCH

Mechanisms of Neurodegeneration and Regeneration in Alcoholism

(2008) F. T. Crews et al.   ALCOHOL AND ALCOHOLISM

Mechanism of alcohol-induced oxidative stress and neuronal injury

(2008) James Haorah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta

(2008) Ryuhei Nagai et al.   JOURNAL OF PINEAL RESEARCH

Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin

(2008) Eloisa Gitto et al.   JOURNAL OF PINEAL RESEARCH