Protein Evolution is Potentially Governed by Protein Stability: Directed Evolution of an Esterase from the Hyperthermophilic Archaeon Sulfolobus tokodaii

Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects

(2016) Gloria Yang et al.   BIOCHEMISTRY

Shifting Fitness and Epistatic Landscapes Reflect Trade-offs along an Evolutionary Pathway

(2016) Barrett Steinberg et al.   JOURNAL OF MOLECULAR BIOLOGY

Epistasis in protein evolution

(2016) Tyler N. Starr et al.   PROTEIN SCIENCE

How mutational epistasis impairs predictability in protein evolution and design

(2016) Charlotte M. Miton et al.   PROTEIN SCIENCE

Environmental changes bridge evolutionary valleys

(2016) B. Steinberg et al.   Science Advances

Dynamics and constraints of enzyme evolution

(2014) Miriam Kaltenbach et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Biophysics of protein evolution and evolutionary protein biophysics

(2014) T. Sikosek et al.   Journal of the Royal Society Interface

Evolvability of Thermophilic Proteins from Archaea and Bacteria

(2013) Kazufumi Takano et al.   BIOCHEMISTRY

Modulating protein stability - directed evolution strategies for improved protein function

(2013) Raymond D. Socha et al.   FEBS Journal

GroEL/ES Buffering and Compensatory Mutations Promote Protein Evolution by Stabilizing Folding Intermediates

(2013) Kirsten T. Wyganowski et al.   JOURNAL OF MOLECULAR BIOLOGY

Mutational effects on stability are largely conserved during protein evolution

(2013) O. Ashenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cumulative Impact of Chaperone-Mediated Folding on Genome Evolution

(2012) David Bogumil et al.   BIOCHEMISTRY

Structure and stability of a thermostable carboxylesterase from the thermoacidophilic archaeonSulfolobus tokodaii

(2012) Clement Angkawidjaja et al.   FEBS Journal

Weak Selection and Protein Evolution

(2012) H. Akashi et al.   GENETICS

Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems

(2011) Thomas J Magliery et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Exploring the interplay of stability and function in protein evolution

(2010) Gustavo Caetano-Anollés et al.   BIOESSAYS

Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins

(2010) Jun Okada et al.   BMC EVOLUTIONARY BIOLOGY

Mutational robustness can facilitate adaptation

(2010) Jeremy A. Draghi et al.   NATURE

Robustness and evolvability in the functional anatomy of a PER-ARNT-SIM (PAS) domain

(2010) A. F. Philip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stability effects of mutations and protein evolvability

(2009) Nobuhiko Tokuriki et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Chaperonin overexpression promotes genetic variation and enzyme evolution

(2009) Nobuhiko Tokuriki et al.   NATURE

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and functional constraints in the evolution of protein families

(2009) Catherine L. Worth et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adaptive landscapes and protein evolution

(2009) M. Carneiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of genetic robustness on evolvability in digital organisms

(2008) Santiago F Elena et al.   BMC EVOLUTIONARY BIOLOGY

Intense Neutral Drifts Yield Robust and Evolvable Consensus Proteins

(2008) Shimon Bershtein et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors

(2008) S.-Y. Son et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Protein Stability and New Functions Trade Off

(2008) Nobuhiko Tokuriki et al.   PLoS Computational Biology