Article
Biology
Jeong Hwa Lee, Mi-Young Lee
Summary: The study investigated the anti-inflammatory activity of Ficus carica fruit extract (FFE) against LPS-stimulated RAW 264.7 cells. FFE showed reduction in nitric oxide (NO) production and iNOS expression, and also decreased fi-hexosaminidase released during allergic reactions. Although FFE did not significantly regulate MAPK and NF kappa B signaling molecules, it dramatically reduced the phosphorylation of JAK1 and STAT3 in the JAK-STAT signaling pathway. FFE was found effective in relieving psoriasis-like skin lesions in mice, indicating its potential as a therapeutic agent against psoriasis.
Article
Biochemistry & Molecular Biology
Elwira Sieniawska, Lukasz Swiatek, Kouadio Ibrahime Sinan, Gokhan Zengin, Anastazja Boguszewska, Malgorzata Polz-Dacewicz, Nabeelah Bibi Sadeer, Ouattara Katinan Etienne, Mohamad Fawzi Mahomoodally
Summary: This study evaluated the biological and chemical properties of Ficus sur Forssk. extracts, revealing their antioxidant, enzyme inhibitory, anticancer, and antiviral activities. The findings provide valuable scientific data for the development of innovative phytopharmaceuticals.
Article
Biochemistry & Molecular Biology
Meriem Amrane-Abider, Mirela Imre, Viorel Herman, Nedjima Debbou-Iouknane, Salima Zemouri-Alioui, Souad Khaled, Cilia Bouiche, Cristina Nerin, Ulas Acaroz, Abdelhanine Ayad
Summary: The objective of this study was to identify the biochemical compounds extracted from OFI flowers and evaluate their antioxidant activities and anticoccidial effects. The results showed that the optimized conditions significantly influenced the phenolic content and antioxidant activities. Molecular analysis revealed the presence of various biophenol classes. The OFI flower extracts inhibited sporulation and damaged the morphology of Eimeria oocysts.
Article
Pharmacology & Pharmacy
Eunjin Sohn, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong
Summary: Extracts of Ficus erecta Thunb. exhibit neuroprotective effects against cognitive deficit and neuronal damage in an amyloid beta-induced Alzheimer's disease mouse model, potentially through activation of the CREB/BDNF signaling pathway and suppression of inflammatory response.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Ana Flavia Burlec, Monica Hancianu, Irina Macovei, Cornelia Mircea, Adrian Fifere, Ioana-Andreea Turin-Moleavin, Cristina Tuchilus, Silvia Robu, Andreia Corciova
Summary: This study presents an environmentally friendly method for synthesizing silver nanoparticles using extracts from Tagetes erecta flowers. The nanoparticles were successfully synthesized through the reduction of silver ions by biocompounds found in the plant. The synthesized nanoparticles were characterized using various techniques, revealing their small size, spherical shape, and stability. Furthermore, the nanoparticles exhibited enhanced antioxidant and antimicrobial activities compared to the initial extracts.
APPLIED SCIENCES-BASEL
(2022)
Article
Plant Sciences
Joel H. Elizondo-Luevano, Ricardo Gomez-Flores, Maria J. Verde-Star, Patricia Tamez-Guerra, Cesar Romo-Saenz, Abelardo Chavez-Montes, Nancy E. Rodriguez-Garza, Ramiro Quintanilla-Licea
Summary: This study evaluated the cytotoxic, antioxidant, and anti-hemolytic activity of 15 plants used in Mexican ethnopharmacology. Results showed that some plant extracts exhibited potential anti-tumor and antioxidant properties.
Article
Biochemistry & Molecular Biology
Weiwei Cao, Junliang Chen, Linlin Li, Guangyue Ren, Xu Duan, Qian Zhou, Mengli Zhang, Danping Gao, Shanshan Zhang, Xu Liu
Summary: The addition of Lonicera japonica extracts significantly increased the chlorogenic acid content in cookies and improved their antioxidant activity. Cookies with a 4% concentration of LJ extracts exhibited the highest antioxidant activity and increased crispiness. Additionally, cookies fortified with a low concentration (1%) of LJ extracts had a higher overall acceptance score.
Article
Biochemistry & Molecular Biology
Ibrahim E. Sallam, Ulrike Rolle-Kampczyk, Stephanie Serena Schaepe, Soumaya S. Zaghloul, Riham S. El-Dine, Ping Shao, Martin von Bergen, Mohamed A. Farag
Summary: This study assessed the effect of gut microbiota on the biotransformation of O. ficus-indica metabolites. The results showed that flavonoid glycosides were converted to two major metabolites, 3-(4-hydroxyphenyl)propanoic acid and phloroglucinol, in vitro at 24 h. In the ex vivo assay, flavonoid glycosides were completely absent in the treated sample, indicating their conversion. The antioxidant potential also declined after biotransformation.
Article
Chemistry, Multidisciplinary
Elzbieta Klewicka, Lidia Piekarska-Radzik, Joanna Milala, Robert Klewicki, Michal Sojka, Natalia Rosol, Anna Otlewska, Bozena Matysiak
Summary: The extracts from Rosa rugosa Thunb. have the ability to inhibit the growth of Staphylococcus spp. bacteria, making them a potential factor for limiting the growth of these bacteria.
APPLIED SCIENCES-BASEL
(2022)
Article
Multidisciplinary Sciences
Lyanne Rodriguez, Andres Trostchansky, Irene Wood, Mauricio Mastrogiovanni, Hermine Vogel, Benita Gonzalez, Mario Marostica Junior, Eduardo Fuentes, Ivan Palomo
Summary: The study revealed that extracts from leaves and unripe fruits of Aristotelia chilensis have antiplatelet activity by inhibiting platelet aggregation and thrombin-induced platelet granule secretion, reducing reactive oxygen species formation, with phenolic and anthocyanin compounds playing a role in these effects.
Article
Plant Sciences
Ichrak Ben-Amor, Bochra Gargouri, Hamadi Attia, Khaoula Tlili, Imen Kallel, Maria Musarra-Pizzo, Maria Teresa Sciortino, Rosamaria Pennisi
Summary: The research demonstrates that olive extracts derived from Olea europaea L. var. sativa have significant antioxidant activity, capable of effectively scavenging free radicals and playing a positive role in preventing and treating various diseases.
Article
Food Science & Technology
Maria Julia Martinez, Adriana Balbina Andreu, Luciana Barbini
Summary: Hepatocellular carcinoma (HCC) is a common and deadly tumor. Late diagnosis and treatment delay contribute to poor prognosis. Polyphenols from potatoes have antioxidant properties and cytotoxic effects on HCC cells, making them a potential treatment option.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Food Science & Technology
Lazar D. Zarkovic, Ksenija S. Mileski, Jelena S. Matejic, Uros M. Gasic, Nemanja F. Rajcevic, Petar D. Marin, Ana M. Dzamic
Summary: This study analyzed the chemical composition, antioxidant, and hypoglycemic activity of Rosa arvensis Huds. leaves and fruits collected from different regions in Serbia. The results showed that leaf extracts had high antioxidant capacity and good alpha-glucosidase inhibitory potential, indicating their potential as novel food ingredients.
Article
Biochemistry & Molecular Biology
Daniela Hanganu, Mihaela Niculae, Irina Ielciu, Neli-Kinga Olah, Melania Munteanu, Ramona Burtescu, Razvan Stefan, Loredana Olar, Emoke Pall, Sanda Andrei, Dan C. Vodnar, Daniela Benedec, Ilioara Oniga
Summary: Syringa vulgaris L., commonly known as common lilac, is a popular ornamental plant that contains bioactive compounds with antioxidant and antitumoral potential. Chemical analyses of its flower, leaves, and bark extracts revealed the presence of various therapeutic compounds, showing significant cytotoxic activity against tumor cell lines.
Article
Horticulture
Clarissa Marcelle Naidoo, Yougasphree Naidoo, Yaser Hassan Dewir, Moganavelli Singh, Aliscia Nicole Daniels, Hassan El-Ramady
Summary: This study investigated the antioxidant potential of leaf, stem, and latex extracts of Tabernaemontana ventricosa and evaluated their cytotoxic activity in HEK293, HeLa, and MCF-7 cell lines. The results showed that all parts of T. ventricosa exhibited strong antioxidant activity, which correlated with cytotoxicity.