A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7

Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1

(2017) Melissa M. Budelier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells

(2017) Doris Höglinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer

(2017) Yasuhiro Horibata et al.   Scientific Reports

The Phosphatidylcholine Transfer Protein Stard7 is Required for Mitochondrial and Epithelial Cell Homeostasis

(2017) Li Yang et al.   Scientific Reports

Shedding Light on Anesthetic Mechanisms

(2016) Kellie A. Woll et al.   ANESTHESIA AND ANALGESIA

Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production

(2016) Jésica Flores-Martín et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ceramide channels and mitochondrial outer membrane permeability

(2016) Marco Colombini   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria

(2016) Yasuhiro Horibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis

(2016) Amrita Jain et al.   JOURNAL OF CELL SCIENCE

Proteome-wide Identification of Novel Ceramide-binding Proteins by Yeast Surface cDNA Display and Deep Sequencing

(2016) Scott Bidlingmaier et al.   MOLECULAR & CELLULAR PROTEOMICS

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions

(2015) Per Haberkant et al.   ACS Chemical Biology

Tumor suppressive functions of ceramide: evidence and mechanisms

(2015) Sehamuddin Galadari et al.   APOPTOSIS

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

(2015) Micah J. Niphakis et al.   CELL

Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

(2015) Andreas Bickert et al.   JOURNAL OF LIPID RESEARCH

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

(2015) Joachim Moser von Filseck et al.   Nature Communications

Regulation of PP2A by Sphingolipid Metabolism and Signaling

(2015) Joshua Oaks et al.   Frontiers in Oncology

Fat & fabulous: Bifunctional lipids in the spotlight

(2014) Per Haberkant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

In Vivo Profiling and Visualization of Cellular Protein-Lipid Interactions Using Bifunctional Fatty Acids

(2013) Per Haberkant et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis

(2013) F. G. Tafesse et al.   JOURNAL OF CELL SCIENCE

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

(2013) Jonathan J Hulce et al.   NATURE METHODS

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

Sphingolipid Signaling in Metabolic Disorders

(2012) Timothy Hla et al.   Cell Metabolism

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

(2012) F.-Xabier Contreras et al.   NATURE

Identification of C6-ceramide-interacting proteins in D6P2T Schwannoma cells

(2012) Venkatesh Kota et al.   PROTEOMICS

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

Fast docking using the CHARMM force field with EADock DSS

(2011) Aurélien Grosdidier et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation

(2011) Hyunmi Lee et al.   PLoS One

Comparative Structural Analysis of Lipid Binding START Domains

(2011) Ann-Gerd Thorsell et al.   PLoS One

Lipids and Cholesterol as Regulators of Traffic in the Endomembrane System

(2010) Jennifer Lippincott-Schwartz et al.   Annual Review of Biophysics

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective

(2010) Nicolas Guex et al.   ELECTROPHORESIS

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

(2010) Oriol Gallego et al.   Molecular Systems Biology

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Glycosphingolipids-Nature, Function, and Pharmacological Modulation

(2009) Tom Wennekes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

StarD7 Mediates the Intracellular Trafficking of Phosphatidylcholine to Mitochondria

(2009) Yasuhiro Horibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the CERT START Domain with Inhibitors Provide Insights into the Mechanism of Ceramide Transfer

(2009) Norio Kudo et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane microdomains: Role of ceramides in the maintenance of their structure and functions

(2008) Galya Staneva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

(2008) Archana Mukhopadhyay et al.   FASEB JOURNAL

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

(2008) N. Kudo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding and release of cholesterol in the Osh4 protein of yeast

(2008) Rishi P. Singh et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Ceramide Biogenesis Is Required for Radiation-Induced Apoptosis in the Germ Line of C. elegans

(2008) X. Deng et al.   SCIENCE