Chymase released from hypoxia-activated cardiac mast cells cleaves human apoA-I at Tyr192and compromises its cardioprotective activity

High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice

(2017) Sarah E. Heywood et al.   Science Translational Medicine

Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats

(2016) Hao Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Correction: Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

(2016) Maurits R. Hollander et al.   PLoS One

Cholesteryl Ester Transfer Protein Inhibition Enhances Endothelial Repair and Improves Endothelial Function in the RabbitSignificance

(2015) Ben J. Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Carboxyl-Terminal Cleavage of Apolipoprotein A-I by Human Mast Cell Chymase Impairs Its Anti-Inflammatory PropertiesSignificance

(2015) Su Duy Nguyen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein A-I mimetic peptide reverses impaired arterial healing after injury by reducing oxidative stress

(2015) Michael A. Rosenbaum et al.   ATHEROSCLEROSIS

The mast cell as a pluripotent HDL-modifying effector in atherogenesis

(2015) Miriam Lee-Rueckert et al.   CURRENT OPINION IN LIPIDOLOGY

Coronary microvascular obstruction in acute myocardial infarction

(2015) Giampaolo Niccoli et al.   EUROPEAN HEART JOURNAL

Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

(2015) Kohei Ashina et al.   PLoS One

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice

(2014) Ilona Kareinen et al.   JOURNAL OF LIPID RESEARCH

HDL endocytosis and resecretion

(2013) Clemens Röhrl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair

(2013) Bing Pan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of signal transduction by HDL

(2013) Chieko Mineo et al.   JOURNAL OF LIPID RESEARCH

Cardioprotective functions of HDLs

(2013) Kerry-Anne Rye et al.   JOURNAL OF LIPID RESEARCH

The role of the gut in reverse cholesterol transport – Focus on the enterocyte

(2013) Miriam Lee-Rueckert et al.   PROGRESS IN LIPID RESEARCH

Lipoprotein remodeling generates lipid-poor apolipoprotein A-I particles in human interstitial fluid

(2012) Norman E. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification of sites in apolipoprotein A-I susceptible to chymase and carboxypeptidase A digestion

(2012) Yoko Usami et al.   BIOSCIENCE REPORTS

Prebeta-1 HDL and coronary heart disease

(2012) John P. Kane et al.   CURRENT OPINION IN LIPIDOLOGY

New insights into the determination of HDL structure by apolipoproteins

(2012) Michael C. Phillips   JOURNAL OF LIPID RESEARCH

Extracellular modifications of HDL in vivo and the emerging concept of proteolytic inactivation of preβ-HDL

(2011) Miriam Lee-Rueckert et al.   CURRENT OPINION IN LIPIDOLOGY

Metabolic and functional relevance of HDL subspecies

(2011) Bela F Asztalos et al.   CURRENT OPINION IN LIPIDOLOGY

Detection of chymase-digested C-terminally truncated apolipoprotein A-I in normal human serum

(2011) Yoko Usami et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Mast cell proteases: multifaceted regulators of inflammatory disease

(2010) G. Pejler et al.   BLOOD

Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function

(2010) Denys Bashtovyy et al.   JOURNAL OF LIPID RESEARCH

Down-regulation of endothelial TLR4 signalling after apo A-I gene transfer contributes to improved survival in an experimental model of lipopolysaccharide-induced inflammation

(2010) Sophie Van Linthout et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Cardiac mast cell proteases do not contribute to the regulation of the rat coronary vascular responsiveness to arterial delivered angiotensin I and II

(2010) Luiz B. Bispo-da-Silva et al.   VASCULAR PHARMACOLOGY

Stimulation of Cell Surface F 1 -ATPase Activity by Apolipoprotein A-I Inhibits Endothelial Cell Apoptosis and Promotes Proliferation

(2009) Claudia Radojkovic et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mast cell-dependent proteolytic modification of HDL particles during anaphylactic shock in the mouse reduces their ability to induce cholesterol efflux from macrophage foam cells ex vivo

(2009) Ilona Judström et al.   ATHEROSCLEROSIS

Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism

(2008) Annina Lyly et al.   HUMAN MOLECULAR GENETICS