Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action

(2017) Kyu-Seon Oh et al.   IMMUNITY

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease

(2017) J. Kenneth Baillie et al.   PLoS Genetics

Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice

(2016) Nathaniel S. Woodling et al.   BRAIN

Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase

(2016) René Fuertig et al.   BRAIN BEHAVIOR AND IMMUNITY

Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients

(2016) Annamaria Cattaneo et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Inflammation Models of Depression in Rodents: Relevance to Psychotropic Drug Discovery

(2016) Jennifer L. Remus et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Transcriptomics in Interferon-α-Treated Patients Identifies Inflammation-, Neuroplasticity- and Oxidative Stress-Related Signatures as Predictors and Correlates of Depression

(2016) Nilay Hepgul et al.   NEUROPSYCHOPHARMACOLOGY

Antidepressant therapies inhibit inflammation and microglial M1-polarization

(2016) Hans O. Kalkman et al.   PHARMACOLOGY & THERAPEUTICS

Neuropathology of mood disorders: do we see the stigmata of inflammation?

(2016) N Mechawar et al.   Translational Psychiatry

Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages

(2016) Linda Huynh et al.   Scientific Reports

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice

(2015) Wenjun Zhou et al.   BRAIN BEHAVIOR AND IMMUNITY

Paroxetine differentially modulates LPS-induced TNFα and IL-6 production in mouse macrophages

(2015) Haritha Durairaj et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Divergent transcriptional activation by glucocorticoids in mouse and human macrophages

(2015) Alasdair Jubb et al.   LANCET

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

Relationship between dopamine deficit and the expression of depressive behavior resulted from alteration of serotonin system

(2015) Minkyung Lee et al.   SYNAPSE

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

(2015) Dora Brites et al.   Frontiers in Cellular Neuroscience

Network dynamics determine the autocrine and paracrine signaling functions of TNF

(2014) Andrew B. Caldwell et al.   GENES & DEVELOPMENT

Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

(2014) S. Raza et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

Association of Serum Interleukin 6 and C-Reactive Protein in Childhood With Depression and Psychosis in Young Adult Life

(2014) Golam M. Khandaker et al.   JAMA Psychiatry

Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing

(2013) Varadharajan Sundaramurthy et al.   Cell Host & Microbe

Enantioselective Analysis of Citalopram and Escitalopram in Postmortem Blood Together with Genotyping for CYP2D6 and CYP2C19

(2013) B. Carlsson et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications

(2013) J.C. Felger et al.   NEUROSCIENCE

Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening

(2013) Domokos Gerö et al.   PLoS One

Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation

(2012) Martina M. Hughes et al.   BRAIN BEHAVIOR AND IMMUNITY

Pig Bone Marrow-Derived Macrophages Resemble Human Macrophages in Their Response to Bacterial Lipopolysaccharide

(2012) R. Kapetanovic et al.   JOURNAL OF IMMUNOLOGY

Depression: an inflammatory illness?: Figure 1

(2012) Rajeev Krishnadas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

(2012) Jingqiu Chen et al.   PLoS One

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(2012) K. Schroder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant Depression

(2012) Charles L. Raison et al.   JAMA Psychiatry

5-HT and the immune system

(2011) Gerard P Ahern   CURRENT OPINION IN PHARMACOLOGY

Association of a polymorphism in the indoleamine- 2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C

(2011) A K Smith et al.   MOLECULAR PSYCHIATRY

Inflammation-Induced Anhedonia: Endotoxin Reduces Ventral Striatum Responses to Reward

(2010) Naomi I. Eisenberger et al.   BIOLOGICAL PSYCHIATRY

Indoleamine 2,3-Dioxygenase

(2010) Hatem Soliman et al.   CANCER JOURNAL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Antidepressants, but not antipsychotics, modulate GR function in human whole blood: An insight into molecular mechanisms

(2010) L.A. Carvalho et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Relationship between the hepatitis C viral load and the serum interferon concentration during the first week of peginterferon-alpha-2b-ribavirin combination therapy

(2010) Catherine François et al.   JOURNAL OF MEDICAL VIROLOGY

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Immunogenicity of Anti-TNF-α Agents in Autoimmune Diseases

(2009) Nádia Emi Aikawa et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Anti-tumor necrosis factor-α therapy is associated with less frequent mood and anxiety disorders in patients with rheumatoid arthritis

(2009) Faruk Uguz et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

(2008) Audrey Kauffmann et al.   BIOINFORMATICS

Norepinephrine-Mediated Suppression of Phagocytosis by Wound Neutrophils

(2008) Ankush Gosain et al.   JOURNAL OF SURGICAL RESEARCH

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

(2008) Anna Yarilina et al.   NATURE IMMUNOLOGY