A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis

Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases

(2014) Qingshan Wang et al.   GLIA

Potent Anti-Inflammatory and Neuroprotective Effects of TGF- 1 Are Mediated through the Inhibition of ERK and p47phox-Ser345 Phosphorylation and Translocation in Microglia

(2014) L. Qian et al.   JOURNAL OF IMMUNOLOGY

Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase

(2014) Q. Wang et al.   JOURNAL OF NEUROSCIENCE

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Developmental origins of central norepinephrine neuron diversity

(2013) Sabrina D Robertson et al.   NATURE NEUROSCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice

(2012) Qingshan Wang et al.   Journal of Neuroinflammation

Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91 phox subunit of NADPH oxidase

(2012) Qingshan Wang et al.   Journal of Neuroinflammation

Extrasynaptic Neurotransmission in the Modulation of Brain Function. Focus on the Striatal Neuronal–Glial Networks

(2012) Kjell Fuxe et al.   Frontiers in Physiology

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway

(2011) Li Qian et al.   JOURNAL OF IMMUNOLOGY

Neurodegeneration and Inflammation in Parkinson's disease

(2011) Sudarshan Phani et al.   PARKINSONISM & RELATED DISORDERS

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The locus coeruleus and noradrenergic modulation of cognition

(2009) Susan J. Sara   NATURE REVIEWS NEUROSCIENCE

Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response

(2009) Michael A. Flierl et al.   PLoS One

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

(2008) Yuxin Liu et al.   NEUROTOXICOLOGY

Noradrenaline provides long-term protection to dopaminergic neurons by reducing oxidative stress

(2003) Jean-Denis Troadec et al.   JOURNAL OF NEUROCHEMISTRY