Constitutively Bound EGFR–Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal

TLR9 stability and signaling are regulated by phosphorylation and cell stress

(2016) Maroof Hasan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

EGFR kinase activity is required for TLR4 signaling and the septic shock response

(2015) S. Chattopadhyay et al.   EMBO REPORTS

Tyrosine phosphorylation in Toll-like receptor signaling

(2014) Saurabh Chattopadhyay et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cutting Edge: The UNC93B1 Tyrosine-Based Motif Regulates Trafficking and TLR Responses via Separate Mechanisms

(2014) Karin Pelka et al.   JOURNAL OF IMMUNOLOGY

Trafficking of endosomal Toll-like receptors

(2014) Bettina L. Lee et al.   TRENDS IN CELL BIOLOGY

Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors

(2014) Surya Pandey et al.   Cold Spring Harbor Perspectives in Biology

UNC93B1 mediates differential trafficking of endosomal TLRs

(2013) Bettina L Lee et al.   eLife

Cofactors Required for TLR7- and TLR9-Dependent Innate Immune Responses

(2012) Chih-yuan Chiang et al.   Cell Host & Microbe

Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling

(2012) M. Yamashita et al.   Science Signaling

Cutting Edge: A TLR9 Cytoplasmic Tyrosine Motif Is Selectively Required for Proinflammatory Cytokine Production

(2011) A. Chockalingam et al.   JOURNAL OF IMMUNOLOGY

Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy

(2011) Jen-Yi Lee et al.   PLoS One

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

(2010) Ingrid Nilsson et al.   EMBO JOURNAL

Plasmacytoid Dendritic Cells Alter the Antitumor Activity of CpG-Oligodeoxynucleotides in a Mouse Model of Lung Carcinoma

(2010) R. Sorrentino et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

(2009) Tang-Cheng Lee et al.   GENESIS

Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes

(2009) K. Yasuda et al.   JOURNAL OF IMMUNOLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Toll-like receptor 9 (TLR9) agonists in the treatment of cancer

(2008) A M Krieg   ONCOGENE