Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid

Molecular mechanisms underlying pimaric acid-induced modulation of voltage-gated K + channels

(2017) Kazuho Sakamoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels

(2017) Fredrik Elinder et al.   Frontiers in Physiology

A drug pocket at the lipid bilayer–potassium channel interface

(2017) Nina E. Ottosson et al.   Science Advances

The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium Channel

(2016) Samira Yazdi et al.   PLoS Computational Biology

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKschannel

(2015) Sara I. Liin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resin-acid derivatives as potent electrostatic openers of voltage-gated K channels and suppressors of neuronal excitability

(2015) Nina E Ottosson et al.   Scientific Reports

Pharmacodynamics of potassium channel openers in cultured neuronal networks

(2014) Calvin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Drug-induced ion channel opening tuned by the voltage sensor charge profile

(2014) Nina E. Ottosson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Dampening of Hyperexcitability in CA1 Pyramidal Neurons by Polyunsaturated Fatty Acids Acting on Voltage-Gated Ion Channels

(2012) Jenny Tigerholm et al.   PLoS One

Tracking a complete voltage-sensor cycle with metal-ion bridges

(2012) U. Henrion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Voltage Gating in Potassium Channels

(2012) M. O. Jensen et al.   SCIENCE

An electrostatic potassium channel opener targeting the final voltage sensor transition

(2011) Sara I. Börjesson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Potassium Channels as a Potential Therapeutic Target for Trigeminal Neuropathic and Inflammatory Pain

(2011) Mamoru Takeda et al.   Molecular Pain

Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations

(2011) L. Delemotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrostatic Tuning of Cellular Excitability

(2010) Sara I. Börjesson et al.   BIOPHYSICAL JOURNAL

Lipoelectric Modification of Ion Channel Voltage Gating by Polyunsaturated Fatty Acids

(2008) Sara I. Börjesson et al.   BIOPHYSICAL JOURNAL

Structure, Function, and Modification of the Voltage Sensor in Voltage-Gated Ion Channels

(2008) Sara I. Börjesson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

K+-Channel Openers Suppress Epileptiform Activities Induced by 4-Aminopyridine in Cultured Rat Hippocampal Neurons

(2008) Kiyoaki Kobayashi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES