Foxp3+T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+T cell response

Regulatory T cells in skin

(2017) Niwa Ali et al.   IMMUNOLOGY

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Targeting CD8+ T cells prevents psoriasis development

(2016) Paola Di Meglio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impaired function of regulatory T cells in patients with psoriasis is mediated by phosphorylation of STAT3

(2016) Luting Yang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing

(2016) Audrey Nosbaum et al.   JOURNAL OF IMMUNOLOGY

Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients

(2015) K. Kurose et al.   CLINICAL CANCER RESEARCH

An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17

(2015) Lynda Grine et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes

(2015) Tiffany C. Scharschmidt et al.   IMMUNITY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

CGAT: computational genomics analysis toolkit

(2014) D. Sims et al.   BIOINFORMATICS

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of anti-CCR4 monoclonal antibody (mogamulizumab) on adult T-cell leukemia-lymphoma: Cutaneous adverse reactions may predict the prognosis

(2014) Kentaro Yonekura et al.   JOURNAL OF DERMATOLOGY

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Balance of Treg vs. T-helper cells in the transition from symptomless to lesional psoriatic skin

(2013) R.R.M.C. Keijsers et al.   BRITISH JOURNAL OF DERMATOLOGY

Stevens-Johnson Syndrome associated with mogamulizumab treatment of adult T-cell leukemia / lymphoma

(2013) Takashi Ishida et al.   CANCER SCIENCE

Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity

(2013) Kevin Goudy et al.   CLINICAL IMMUNOLOGY

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Responses and Genital Tract Inflammation upon Intracellular Chlamydia muridarum Infection

(2013) J. M. Moore-Connors et al.   JOURNAL OF IMMUNOLOGY

CD8 T Cells and IFN-γ Emerge as Critical Players for Psoriasis in a Novel Model of Mouse Psoriasiform Skin Inflammation

(2013) Paola Di Meglio et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Langerinneg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice

(2013) C. Wohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldara activates TLR7-independent immune defence

(2013) Anne Walter et al.   Nature Communications

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

(2012) Stanislav Pantelyushin et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction and exacerbation of psoriasis with Interferon-alpha therapy for hepatitis C: A review and analysis of 36 cases

(2012) M. Afshar et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Psoriasis

(2011) Gayathri K. Perera et al.   Annual Review of Pathology-Mechanisms of Disease

Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis

(2011) Marie-José Bijlmakers et al.   HUMAN MOLECULAR GENETICS

CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model

(2011) Pushpa Pandiyan et al.   IMMUNITY

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

(2011) Yihua Cai et al.   IMMUNITY

GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice

(2011) Elizabeth A. Wohlfert et al.   JOURNAL OF CLINICAL INVESTIGATION

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Dark Side of Regulatory T Cells in Psoriasis

(2011) David C. Soler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of CD4+CD25high+FOXP3+Regulatory T Cells in Psoriasis

(2010) Woo-Jin Yun et al.   Annals of Dermatology

A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti–interferon-alfa monoclonal antibody, in subjects with chronic psoriasis

(2010) Robert Bissonnette et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

(2009) L. van der Fits et al.   JOURNAL OF IMMUNOLOGY

Psoriasis during interferon beta treatment for multiple sclerosis

(2009) Loredana La Mantia et al.   NEUROLOGICAL SCIENCES

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Cutaneous manifestations of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome

(2008) M. Halabi-Tawil et al.   BRITISH JOURNAL OF DERMATOLOGY