Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

(2016) Marius R. Robciuc et al.   Cell Metabolism

Myeloid-Epithelial-Reproductive Receptor Tyrosine Kinase and Milk Fat Globule Epidermal Growth Factor 8 Coordinately Improve Remodeling After Myocardial Infarction via Local Delivery of Vascular Endothelial Growth FactorCLINICAL PERSPECTIVE

(2016) Kiave-Yune Howangyin et al.   CIRCULATION

Endocrine vasculatures are preferable targets of an antitumor ineffective low dose of anti-VEGF therapy

(2016) Yin Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

(2016) Takahiro Seki et al.   Nature Communications

Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism

(2016) Yunlong Yang et al.   Nature Communications

Flt1/VEGFR1 heterozygosity causes transient embryonic edema

(2016) Yasunori Otowa et al.   Scientific Reports

Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis

(2015) Shang Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice

(2015) Matthew J. During et al.   ENDOCRINOLOGY

VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients

(2015) Xiaojuan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy

(2015) Jianbo He et al.   Journal of Ophthalmology

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors

(2015) H. Iwamoto et al.   Science Advances

VEGF-VEGFR Signals in Health and Disease

(2014) Masabumi Shibuya   Biomolecules & Therapeutics

Reducing Macrophage Proteoglycan Sulfation Increases Atherosclerosis and Obesity through Enhanced Type I Interferon Signaling

(2014) Philip L.S.M. Gordts et al.   Cell Metabolism

Gp130 Signaling Promotes Development of Acute Experimental Colitis by Facilitating Early Neutrophil/Macrophage Recruitment and Activation

(2014) L. E. Sander et al.   JOURNAL OF IMMUNOLOGY

Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues

(2014) J. Honek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGFR2-Mediated Vascular Dilation as a Mechanism of VEGF-Induced Anemia and Bone Marrow Cell Mobilization

(2014) Sharon Lim et al.   Cell Reports

Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis

(2013) Mei Dong et al.   Cell Metabolism

Adipose Vascular Endothelial Growth Factor Regulates Metabolic Homeostasis through Angiogenesis

(2013) Hoon-Ki Sung et al.   Cell Metabolism

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues

(2013) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis

(2013) Kayoko Hosaka et al.   Nature Communications

The Vascular Endothelium of the Adipose Tissue Gives Rise to Both White and Brown Fat Cells

(2012) Khanh-Van Tran et al.   Cell Metabolism

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

(2012) Yanqiu Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice

(2012) Sharon Lim et al.   Nature Protocols

Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases

(2012) D. P. Kodack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dichotomous effects of VEGF-A on adipose tissue dysfunction

(2012) K. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

(2011) Abigail F. Welford et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

VEGFR-1 Signaling Regulates the Homing of Bone Marrow-Derived Cells in a Mouse Stroke Model

(2010) Heike Beck et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Hypoxia-induced metastasis model in embryonic zebrafish

(2010) Pegah Rouhi et al.   Nature Protocols

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

(2009) Yuan Xue et al.   Cell Metabolism

Positive and Negative Modulation of Angiogenesis by VEGFR1 Ligands

(2009) Y. Cao   Science Signaling

Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents

(2008) Yuval Shaked et al.   CANCER CELL

Flt-1 Signaling in Macrophages Promotes Glioma Growth In vivo

(2008) M. Kerber et al.   CANCER RESEARCH

White Fat Progenitor Cells Reside in the Adipose Vasculature

(2008) W. Tang et al.   SCIENCE