Cyclizing-berberine A35 induces G2/M arrest and apoptosis by activating YAP phosphorylation (Ser127)

Effect of YAP Inhibition on Human Leukemia HL-60 Cells

(2017) Min Chen et al.   International Journal of Medical Sciences

Knockdown of Yes-Associated Protein Induces the Apoptosis While Inhibits the Proliferation of Human Periodontal Ligament Stem Cells through Crosstalk between Erk and Bcl-2 Signaling Pathways

(2017) Yong Wen et al.   International Journal of Medical Sciences

Phosphorylation by NLK inhibits YAP‐14‐3‐3‐interactions and induces its nuclear localization

(2016) Sungho Moon et al.   EMBO REPORTS

Sophoridinol derivative 05D induces tumor cells apoptosis by topoisomerase1-mediated DNA breakage

(2016) Wuli Zhao et al.   OncoTargets and Therapy

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

YAP Regulates S-Phase Entry in Endothelial Cells

(2015) Zhewei Shen et al.   PLoS One

CFAssay: statistical analysis of the colony formation assay

(2015) Herbert Braselmann et al.   Radiation Oncology

Brief Reports: Controlling the Survival of Human Pluripotent Stem Cells by Small Molecule-Based Targeting of Topoisomerase IIAlpha

(2015) Uri Ben-David et al.   STEM CELLS

The dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2α by enhancing pre-strand and post-strand cleavage and inhibiting DNA religation

(2015) Wuli Zhao et al.   Oncotarget

YAP controls retinal stem cell DNA replication timing and genomic stability

(2015) Pauline Cabochette et al.   eLife

c-Abl antagonizes the YAP oncogenic function

(2014) R Keshet et al.   CELL DEATH AND DIFFERENTIATION

Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers

(2014) Francesca Cottini et al.   NATURE MEDICINE

Topoisomerase IIα in chromosome instability and personalized cancer therapy

(2014) T Chen et al.   ONCOGENE

CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation

(2013) S. Yang et al.   CANCER RESEARCH

Myofibrillogenesis regulator-1 promotes cell adhesion and migration in human hepatoma cells

(2013) WuLi Zhao et al.   CHINESE SCIENCE BULLETIN

Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents

(2013) Yang-Biao Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation

(2013) W Zhao et al.   Blood Cancer Journal

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

(2008) Jiahao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increased efficiency for performing colony formation assays in 96-well plates: novel applications to combination therapies and high-throughput screening

(2008) David Katz et al.   BIOTECHNIQUES

Mitotic catastrophe is the predominant response to histone acetyltransferase depletion

(2008) G-H Ha et al.   CELL DEATH AND DIFFERENTIATION