标题
Zinc binding groups for histone deacetylase inhibitors
作者
关键词
-
出版物
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Volume 33, Issue 1, Pages 714-721
出版商
Informa UK Limited
发表日期
2018-04-04
DOI
10.1080/14756366.2017.1417274
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phase II study of MGCD0103 in patients with relapsed follicular lymphoma (FL): Study reinitiation and update of clinical efficacy and safety.
- (2017) R. E. Martell et al. JOURNAL OF CLINICAL ONCOLOGY
- Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1 H -pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study
- (2016) Jiachen Wen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibitors of histone deacetylase as antitumor agents: A critical review
- (2016) Mohammed Manal et al. BIOORGANIC CHEMISTRY
- Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors
- (2016) Alexander Kleinschek et al. ChemMedChem
- Inside HDACs with more selective HDAC inhibitors
- (2016) Joëlle Roche et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia
- (2016) Jesse J. McClure et al. JOURNAL OF MEDICINAL CHEMISTRY
- Computational Design of a Time-Dependent Histone Deacetylase 2 Selective Inhibitor
- (2015) Jingwei Zhou et al. ACS Chemical Biology
- Targeting Histone Deacetylases in Diseases: Where Are We?
- (2015) Rosaria Benedetti et al. ANTIOXIDANTS & REDOX SIGNALING
- Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors
- (2015) Loana Musso et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Identification of Histone Deacetylase Inhibitors with Benzoylhydrazide Scaffold that Selectively Inhibit Class I Histone Deacetylases
- (2015) Yunfei Wang et al. CHEMISTRY & BIOLOGY
- Histone Deacetylase Inhibitors: Potent Anti-Leukemic Agents
- (2015) Jiang Bian et al. CURRENT MEDICINAL CHEMISTRY
- A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
- (2015) Andra V. Krauze et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- HDAC8: a multifaceted target for therapeutic interventions
- (2015) Alokta Chakrabarti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Discovery of a new class of histone deacetylase inhibitors with a novel zinc binding group
- (2015) Youxuan Li et al. MedChemComm
- Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor
- (2015) Loredana Vesci et al. Oncotarget
- ST7612AA1, a Thioacetate-ω(γ-lactam carboxamide) Derivative Selected from a Novel Generation of Oral HDAC Inhibitors
- (2014) Giuseppe Giannini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Trend of Histone Deacetylase Inhibitors in Cancer Therapy: Isoform Selectivity or Multitargeted Strategy
- (2014) Lei Zhang et al. MEDICINAL RESEARCH REVIEWS
- 3-Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition
- (2013) Vishal Patil et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group
- (2013) Mercedes Lobera et al. Nature Chemical Biology
- Tropolones As Lead-Like Natural Products: The Development of Potent and Selective Histone Deacetylase Inhibitors
- (2013) Sophia N. Ononye et al. ACS Medicinal Chemistry Letters
- OT3-01-06: A Phase 2 Study Investigating the Safety, Efficacy and Surrogate Biomarkers of Response of 5-Azacitidine (5-AZA) and Entinostat (MS-275) in Patients with Advanced Breast Cancer.
- (2012) RM Connolly et al. CANCER RESEARCH
- Panobinostat for the treatment of multiple myeloma
- (2012) Paola Neri et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives
- (2012) Giuseppe Giannini et al. Future Medicinal Chemistry
- A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold
- (2011) Melissa M. Kemp et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: Implication for HIV-associated neurocognitive disorder (HAND)
- (2011) Zainulabedin M. Saiyed et al. NEUROCHEMISTRY INTERNATIONAL
- Developing novel non-hydroxamate histone deacetylase inhibitors: the chelidamic warhead
- (2011) Sergio Valente et al. MedChemComm
- Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
- (2010) T. Roger et al. BLOOD
- A Structure-Based Virtual Screening Approach toward the Discovery of Histone Deacetylase Inhibitors: Identification of Promising Zinc-Chelating Groups
- (2010) Hwangseo Park et al. ChemMedChem
- Simple and Efficient Synthesis of Belinostat
- (2010) Lei Yang et al. SYNTHETIC COMMUNICATIONS
- Histone deacetylase inhibitors and HIV latency
- (2010) David M Margolis Current Opinion in HIV and AIDS
- Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
- (2010) Julia M. Wagner et al. Clinical Epigenetics
- Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model
- (2009) Barbara Attenni et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Phase II study of the histone deacetylase inhibitor MGCD0103 in patients with previously treated chronic lymphocytic leukaemia
- (2009) Kristie A. Blum et al. BRITISH JOURNAL OF HAEMATOLOGY
- Histone Deacetylase Inhibitors and Neurodegenerative Disorders: Holding the Promise
- (2009) Antonello Mai et al. CURRENT PHARMACEUTICAL DESIGN
- Significant Associations of Mismatch Repair Gene Polymorphisms With Clinical Outcome of Pancreatic Cancer
- (2009) Xiaoqun Dong et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia
- (2008) G. Garcia-Manero et al. BLOOD
- Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure
- (2008) Pasquale Gallo et al. CARDIOVASCULAR RESEARCH
- Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay
- (2008) C. Bonfils et al. CLINICAL CANCER RESEARCH
- Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
- (2008) Aleksey G. Kazantsev et al. NATURE REVIEWS DRUG DISCOVERY
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