期刊
JOURNAL OF DRUG TARGETING
卷 27, 期 2, 页码 145-163出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/1061186X.2018.1474360
关键词
Adoptive T-cell therapy; tumour microenvironment; immunotherapy; cancer; particulate systems
Immunotherapy holds tremendous promise for improving cancer treatment in which an appropriate stimulator may naturally trigger the immune system to control cancer. Up-to-date, adoptive T-cell therapy has received two new FDA approvals that provide great hope for some cancer patient groups. Nevertheless, expense and safety-related issues require further study to obtain insight into targets for efficient immunotherapy. The development of material science was largely responsible for providing a promising horizon to strengthen immunoengineering. In this review, we focus on T-cell characteristics in the context of the immune system against cancer and discuss several approaches of exploiting engineered particles to manipulate the responses of T cells and the tumour microenvironment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据