Article
Health Care Sciences & Services
Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Andreea Amuzescu, Clara Matei, Mircea Tampa
Summary: This study evaluated the efficacy of sertaconazole 2% cream in patients with seborrheic dermatitis. The results showed that sertaconazole treatment was associated with a higher percentage of patients with mild symptoms and a lower percentage of patients with moderate or severe symptoms compared to other treatments. Sertaconazole may be an efficient alternative therapy for seborrheic dermatitis.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Microbiology
Juanjuan Li, Yahui Feng, Chen Liu, Zhiya Yang, Sybren de Hoog, Yuying Qu, Biao Chen, Dongmei Li, Huabao Xiong, Dongmei Shi
Summary: The study found a positive correlation between Malassezia hyphae and the clinical severity of Seborrheic dermatitis (SD) patients, with all patients responding well to antifungal treatment. Species dominance did not significantly differ across variant groups. Further exploration is needed on the exact molecular mechanisms of how Malassezia spp. affect SD.
MICROBIOLOGY SPECTRUM
(2022)
Article
Dermatology
Jannik Rousel, Andreea Nadaban, Mahdi Saghari, Lisa Pagan, Ahnjili Zhuparris, Bart Theelen, Tom Gambrah, Hein E. C. van Der Wall, Rob J. Vreeken, Gary L. Feiss, Tessa Niemeyer-van der Kolk, Jacobus Burggraaf, Martijn B. A. van Doorn, Joke A. Bouwstra, Robert Rissmann
Summary: Seborrheic dermatitis is a chronic inflammatory skin disease characterized by skin barrier dysfunction and changes in ceramide composition. This study found a correlation between barrier impairment and inflammation in seborrheic dermatitis, suggesting that restoring the cutaneous barrier could be a potential therapeutic approach.
EXPERIMENTAL DERMATOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Qingbin Lin, Ananth Panchamukhi, Pan Li, Wang Shan, Hongwei Zhou, Lihua Hou, Wei Chen
Summary: Seborrheic dermatitis (SD) is a common disease of the human scalp, with dysbiosis of the scalp microbiome being associated with SD. Specific fungi and bacteria have been identified as potential biomarkers for SD. The etiology of SD is multi-pathogenetic-dependent on the linkage of several microbes with host.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Review
Infectious Diseases
Iniobong Chukwuebuka Ikenna Ugochukwu, Wafa Rhimi, Wissal Chebil, Antonio Rizzo, Maria Tempesta, Gustavo Giusiano, Raul Fernando Mejia Tabora, Domenico Otranto, Claudia Cafarchia
Summary: Malassezia yeasts are part of the skin mycobiota and can become opportunistic pathogens, causing various skin disorders. The interaction between the host skin and Malassezia spp. leads to the production of virulence factors or metabolites that contribute to the development of different clinical presentations of skin disorders.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
(2023)
Article
Dermatology
Nilhan Atsu, Cagri Ergin, Nazli Caf, Zafer Turkoglu, Aylin Dogen, Macit Ilkit
Summary: The study compared the performance of FastFung agar and mDixon agar in culturing Malassezia species among different groups, finding that FastFung agar was superior in isolating M. furfur and comparable to mDixon agar in isolating non-M. furfur species.
Article
Mycology
Mervat Hamdino, Amany Ahmed Saudy, Laila Hussein El-Shahed, Mohamed Taha
Summary: This study identified Malassezia species in lesions of patients with pityriasis versicolor, atopic dermatitis, and seborrheic dermatitis, as well as corresponding sites in healthy subjects, using culture methods. The study found that M. furfur was a common isolated species in all groups, while M. sympodialis was the prevalent species in atopic dermatitis lesions.
JOURNAL DE MYCOLOGIE MEDICALE
(2022)
Article
Dermatology
P. Lindso Andersen, G. B. Jemec, C. Erikstrup, M. Didriksen, K. M. Dinh, S. Mikkelsen, E. Sorensen, K. R. Nielsen, M. T. Bruun, H. Hjalgrim, T. F. Hansen, S. G. Saekmose, S. R. Ostrowski, D. M. L. Saunte, O. B. Pedersen
Summary: This study investigated the association between HLA alleles and MRSD, identifying five novel associations and confirming one previous association.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
Ayse N. Atsu, Nazli Caf, Zafer Turkoglu, Defne Ozkoca, Ozan Yildirim, Cagri Ergin
Summary: This study compared the differences of Malassezia species in the maskne region and found that they were more commonly isolated from the nasolabial region of acne and seborrheic dermatitis patients. These findings suggest that the increasing numbers of Malassezia species will trigger an inflammation with an antibody reaction, which can facilitate the treatment of resistant acne and seborrheic dermatitis.
INDIAN JOURNAL OF DERMATOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jannik Rousel, Mahdi Saghari, Lisa Pagan, Andreea Nadaban, Tom Gambrah, Bart Theelen, Marieke L. de Kam, Jorine Haakman, Hein E. C. van der Wall, Gary L. Feiss, Tessa Niemeyer-van der Kolk, Jacobus Burggraaf, Joke A. Bouwstra, Robert Rissmann, Martijn B. A. van Doorn
Summary: This study evaluated the effectiveness of omiganan in the treatment of facial seborrheic dermatitis. The results showed that omiganan did not significantly improve clinical symptoms or other biomarkers. In contrast, ketoconazole significantly reduced disease severity and had positive effects on Malassezia abundances, microbial diversity, and skin barrier function. The importance of evaluating omiganan in the treatment of facial seborrheic dermatitis is limited.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Veterinary Sciences
Evi I. Sofou, Svetlina Aleksandrova, Elisa Badulescu, Manolis Chatzis, Manolis Saridomichelakis
Summary: This study evaluated the change in skin lesions and pruritus, as well as the overall efficacy of antimicrobial treatment, in dogs with atopic dermatitis and skin infections. The results showed a significant decrease in the severity of skin lesions and pruritus. The efficacy of antimicrobial treatment was assessed as good to excellent by both the clinician and the owner. However, there was high variability in the response to treatment among dogs.
VETERINARY SCIENCES
(2022)
Review
Dermatology
Resmi Mustarichie, Tina Rostinawati, Dian Ayu Eka Pitaloka, Nyi Mekar Saptarini, Yoppi Iskandar
Summary: Seborrhea dermatitis is a common skin disorder that can be treated with antifungal, anti-inflammatory, and other therapies. Research on medicinal plants provides potential for developing new treatment agents.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2022)
Article
Chemistry, Medicinal
Viktor A. Filatov, Olesya Yu. Kulyak, Elena I. Kalenikova
Summary: A novel substance based on M. alternifolia leaf oil, 1,8-cineole, and (-)-alpha-bisabolol showed antimicrobial activity against SD-related microorganisms, making it a potential treatment for dandruff and SD.
Article
Dermatology
Maria Fernanda Ordonez-Rubiano, Mirian Casas, Valentina Balaguera-Orjuela
Summary: This case series reports a positive response to oral or topical antifungals in atopic dermatitis patients treated with Dupilumab and developing Dupilumab facial redness, which supports the Malassezia hypersensitivity theory.
DERMATOLOGIC THERAPY
(2021)
Article
Dermatology
Pascal Joly, Ines Tejedor, Florence Tetart, Helene Collas Cailleux, Alice Barrel, Paul Arnaud De Preville, Nathalie Mion-Mouton, Germaine Gabison, Sophie Baricault, Catherine Girardin Tordeur, Martin Xavier Dore, Bernard Rossi, Catherine Bourseau-Quetier, Melanie Chamaillard, Sandra Ly, Olivier Chosidow, Marie-Aleth Richard-Lallemand, Jean-Claude Rzeznik, Jean-Michel Amici, Guillaume Lair, Sylvie Bechu, Jacques Benichou, Caroline Thill, Marie Beylot-Barry
Summary: This study suggests that tacrolimus 0.1% ointment is more effective than ciclopiroxolamine 1% cream as maintenance therapy for patients with severe seborrheic dermatitis. Patients in the tacrolimus group had a longer duration of complete remission and lower risk of relapse compared to those in the ciclopiroxolamine group.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)