Article
Dentistry, Oral Surgery & Medicine
Alberto Monje, Gonzalo Blasi, Ettore Amerio, Ignacio Sanz-Martin, Jose Nart
Summary: This study investigated dimensional changes in free epithelialized gingival/mucosal grafts and their influencing factors. The results showed that the grafts experienced a reduction of approximately 40% in size over a 6-month follow-up period, with greater changes observed at implant sites compared to tooth sites.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Medicine, General & Internal
Puneeta Arya, Sjirk J. Westra, Oscar J. Benavidez, Marc D. Natter, Mandakolathur R. Murali
Summary: This passage describes the case of a 17-year-old boy who was admitted to the ICU with chest pain. He had developed symptoms such as fever, nausea, diarrhea, muscle aches, and chest pain 5 days prior.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Maria Baus-Dominguez, Raquel Gomez-Diaz, Daniel Torres-Lagares, Jose-Luis Gutierrez-Perez, Guillermo Machuca-Portillo, Maria-Angeles Serrera-Figallo
Summary: This retrospective case-control study aimed to identify possible genes related to inflammatory responses, bone metabolism, and bone quality in Down syndrome patients with dental implant failure. Five genes were identified as statistically significant, suggesting a genetic susceptibility in this patient group.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Francesco Corrado, Simone Marconcini, Saverio Cosola, Enrica Giammarinaro, Ugo Covani
Summary: Significant alveolar bone resorption occurs after tooth extraction, and immediate implant placement alone is not enough to prevent this. This study reports the successful outcome of using a custom healing abutment for an immediate implant, which helped maintain soft tissue and promote bone regeneration even after 5 years. The use of an interim customized healing abutment can prevent tissue collapse and is a potential preservation strategy without the need for additional grafting. Further studies are needed to confirm these findings.
JOURNAL OF ORAL IMPLANTOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Junyu Chen, Jin Wang, Xinjie Wu, Nils Simon, Camilla I. Svensson, Juan Yuan, David A. Hart, Aisha S. Ahmed, Paul W. Ackermann
Summary: Outcomes after human dense connective tissue (DCT) repair vary and are often not optimal, leading to compromised function and chronic degenerative diseases. The biomarkers and mechanisms guiding good clinical outcomes after DCT injuries are mostly unknown. This study characterizes the proteomic landscape of DCT repair following human Achilles tendon rupture and identifies a novel prognostic biomarker, eEF2, which positively regulates autophagy, cell proliferation and migration, as well as reduces cell death and apoptosis for improved DCT repair and outcomes.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2023)
Article
Chemistry, Physical
Marc Balmer, Carolin Fischer, Miha Pirc, Christoph H. F. Hammerle, Ronald E. Jung
Summary: The study evaluated the performance of a short, 1-piece, zirconia implant after 1 year of function. 46 implants were placed in 47 patients, with 2 lost during the healing phase and another lost after loading, resulting in a 93% survival rate after 1 year. The implants showed stable marginal bone levels and no signs of peri-implantitis.
Article
Chemistry, Multidisciplinary
Noemi Dirzu, Ondine Lucaciu, Dan Sebastian Dirzu, Olga Soritau, Diana Cenariu, Bogdan Crisan, Lucia Tefas, Radu Septimiu Campian
Summary: Bone regeneration is a key focus in maxillofacial research, with exogenous delivery of growth factors, such as BMP-2, through liposomes showing potential in enhancing bone integration and quality. This literature review explores the scientific data on BMP-2 delivery using liposomes, suggesting a promising strategy for future clinical practice.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Medicinal
Jean Marcos De Souza, Thiago Junqueira Trevisan, Samara Rosa Sepresse, Ana Carolina Londe, Marcondes Cavalcante Franca Junior, Simone Appenzeller
Summary: Peripheral neuropathy (PN) is a common challenge in the clinical practice of systemic rheumatic diseases. This literature review provides a comprehensive approach to the diagnosis and management of PN related to systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, and systemic vasculitis, including evidence-based treatment strategies.
Article
Dentistry, Oral Surgery & Medicine
Claudio Stacchi, Giuseppe Troiano, Antonio Rapani, Teresa Lombardi, Rosario Sentineri, Stefano Speroni, Federico Berton, Roberto Di Lenarda
Summary: The study evaluated the prevalence of peri-implantitis in implants inserted in augmented maxillary sinuses and found that a history of periodontitis, sinus elevation with a lateral approach, and one-stage sinus floor elevation were significantly correlated with the occurrence of peri-implantitis.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Vaclav Babuska, Phanindra Babu Kasi, Petra Chocholata, Lucie Wiesnerova, Jana Dvorakova, Radana Vrzakova, Anna Nekleionova, Lukas Landsmann, Vlastimil Kulda
Summary: Nanomaterials have great potential in the field of bone tissue engineering, and this review article focuses on their application and research progress in the purpose of bone repair and regeneration. It provides an overview of bone biology and discusses nanostructured materials and different types of nanoparticles.
APPLIED SCIENCES-BASEL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Eugenio Velasco-Ortega, Nicola Alberto Valente, Giovanna Iezzi, Morena Petrini, Giacomo Derchi, Antonio Barone
Summary: Lateral maxillary sinus augmentation is a predictable bone regeneration technique, and its success depends on the surgeon's skill and the characteristics of the biomaterial used. The study found no significant difference in new bone percentage between groups, but the control group had more residual biomaterial and less nonmineralized tissue.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Article
Immunology
Michael Heming, Louisa Mueller-Miny, Leoni Rolfes, Andreas Schulte-Mecklenbeck, Tobias J. Brix, Julian Varghese, Marc Pawlitzki, Hermann Pavenstaedt, Martin A. Kriegel, Catharina C. Gross, Heinz Wiendl, Gerd Meyer zu Hoerste
Summary: By studying immune cell compositions using flow cytometry, this study found that an expansion of plasma cells in the blood can be used to distinguish connective tissue diseases (CTD) with neurological manifestations from clinically similar diseases. This provides a new method for the differential diagnosis of CTD.
JOURNAL OF NEUROINFLAMMATION
(2023)
Article
Endocrinology & Metabolism
T. Grandi, F. Casotto, D. Mani, L. Signorini
Summary: This retrospective study aimed to evaluate the mid-term outcome of using standard implants with 20 to 24 mm length in immediate function for prosthetic rehabilitation of complete edentulous jaws with low bone density. The results showed that long implants (>= 20 mm) provided successful treatment outcomes with improved prosthetic function for patients with low bone density and complete edentulism.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Article
Immunology
Huyan Wang, Xiaowei Shi, Huanhuan Yang, Yan Du, Jing Xue
Summary: This study compared the diagnostic value of metagenomic next-generation sequencing (mNGS) shotgun and conventional microbiological tests in determining infections in patients with connective tissue diseases (CTDs). The results showed that mNGS had a high sensitivity in identifying infectious pathogens and performed well in detecting mixed infections. Additionally, mNGS was effective in detecting Pneumocystis jirovecii infections, which are closely associated with low CD4+ T-cell counts. Therefore, mNGS is an important tool for diagnosing infections and guiding treatment in CTDs patients.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Dermatology
Joonho Shim, Se Jin Oh, Eunhye Yeo, Ji Hye Park, Jai Hee Bae, Seok-Hyung Kim, Dongyoun Lee, Jong Hee Lee
Summary: In this study, single-cell RNA sequencing and spatial transcriptomics were used to uncover the underlying pathophysiology of keloids. The results revealed cellular heterogeneity, cell-cell interactions, and mesenchymal activation of endothelial cells, which may play a role in the development of keloids.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
