Article
Oncology
Julie Hallet, Jesse Zuckerman, Matthew P. Guttman, Tyler R. Chesney, Barbara Haas, Alyson Mahar, Antoine Eskander, Wing C. Chan, Amy Hsu, Victoria Barabash, Natalie Coburn
Summary: Patient-reported symptom burden remains stable for up to 1 year after cancer surgery among older adults, with neither surgery nor adjuvant therapy coinciding with a worsening in symptom burden. However, the persistence of symptoms at 1 year may suggest gaps in supportive care for older adults.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Atul Batra, Lin Yang, Devon J. Boyne, Andrew Harper, Winson Y. Cheung, Colleen A. Cuthbert
Summary: A single assessment of baseline symptom burden using the ESASr in patients with metastatic cancer has significant prognostic value. Factors such as older age, male sex, primary lung cancer, and smoking are predictive of inferior overall survival. This study's findings contribute to the routine collection of patient-reported outcomes in real-world clinical settings.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Julie Hallet, Rinku Sutradhar, Elie Isenberg-Grzeda, Christopher W. Noel, Alyson L. Mahar, Simone N. Vigod, James Bolton, Julie Deleemans, Wing C. Chan, Natalie G. Coburn, Antoine Eskander
Summary: In this case-control study, moderate to severe anxiety, depression, shortness of breath, and increasing t-ESAS score after cancer diagnosis were found to be associated with higher odds of nonfatal self-injury (NFSI) in the following 180 days.
Article
Health Care Sciences & Services
Josephine J. Koldenhof, Frederieke H. van der Baan, Elisabeth G. Verberne, Annemarleen M. Kamphuis, Rik J. Verheijden, Erwin H. Tonk, Anne S. van Lindert, Janneke van der Stap, Saskia C. Teunissen, Petronella O. Witteveen, Karjin P. Suijkerbuijk
Summary: This study examined the symptoms and impact of immune-related adverse events (irAEs) on health-related quality of life (HRQL) in patients with melanoma or non-small lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICI). The results showed that the prevalence of symptoms decreased during treatment, and patients generally reported a low influence of side effects on HRQL. However, a higher number of clinically relevant symptoms was associated with poorer wellbeing in patients.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Oncology
Anita D'Souza, Ruta Brazauskas, Angela Dispenzieri, Julie Panepinto, Kathryn E. Flynn
Summary: In a prospective cohort study of newly diagnosed systemic light chain (AL) amyloidosis patients, patient-reported outcomes (PROs) were found to fluctuate in the first year of treatment, with domains related to 1-year survival including physical function, fatigue, anxiety, depression, and social roles. The study underscores the importance of measuring and tracking PROs in clinical care and research.
BLOOD CANCER JOURNAL
(2021)
Article
Oncology
Li Tang, Hongfan Yu, Wei Dai, Xiaojun Yang, Xing Wei, Xin Shelley Wang, Charles S. S. Cleeland, Qiang Li, Qiuling Shi
Summary: This study analyzed symptom trajectories after lung cancer surgery to understand patient heterogeneity and identify patients in need of extensive care.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Ola Ahmed, Angela Lee, Neeta Vachharajani, Su-Hsin Chang, Yikyung Park, Adeel S. Khan, William C. Chapman, M. B. Majella Doyle
Summary: This study aimed to assess health-related quality of life (HRQoL) after liver transplantation (LT) using the Patient-Reported Outcomes Measurement Information System (PROMIS). The results showed that although overall patient well-being can improve, some mental health domains require further consideration during the postoperative period.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Article
Oncology
Xin Shelley Wang, Kelly K. Bree, Neema Navai, Mona Kamal, Shu-En Shen, Elizabeth Letona, Charles S. Cleeland, Qiuling Shi, Vijaya Gottumukkala
Summary: This study used the MD Anderson Symptom Inventory to assess symptom burden and functioning status for bladder cancer patients for 3 months post-radical cystectomy. The study found that patients with more severe symptom burden at baseline and discharge had poorer functional recovery postoperatively. These symptoms can be used to identify bladder cancer patients at higher risk for poor functional recovery during the perioperative period.
Article
Oncology
Linda Victoria Eriksson, Katarina Holmberg, Carina Lundh Hagelin, Yvonne Wengstrom, Karin Bergkvist, Jeanette Winterling
Summary: This study aimed to investigate patient-reported symptom burden in the first year after allo-HSCT and examine whether a high symptom burden 4 months after allo-HSCT predicts recovery, including general health and sick leave, 1 year after transplantation.
Article
Oncology
Carolyn L. Qian, Emilia R. Kaslow-Zieve, Chinenye C. Azoba, Nora Horick, Irene Wang, Emily Van Seventer, Richard Newcomb, Barbara J. Cashavelly, Vicki A. Jackson, David P. Ryan, Joseph A. Greer, Areej El-Jawahri, Jennifer S. Temel, Ryan D. Nipp
Summary: Hospitalized patients with cancer report high care satisfaction, which is associated with older age and admission to a dedicated oncology service. Higher satisfaction is associated with lower symptom burden and shorter hospital length of stay, highlighting the importance of improving symptom management and care coordination in this population.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Cardiac & Cardiovascular Systems
Adrienne H. Kovacs, Gerald Lebovic, Stavroula Raptis, Samuel Blais, Christopher A. Caldarone, Nagib Dahdah, Frederic Dallaire, Christian Drolet, Jasmine Grewal, Camille L. Hancock Friesen, Edward Hickey, Gauri Rani Karur, Paul Khairy, Benedetta Leonardi, Michelle Keir, Brian W. McCrindle, Syed Najaf Nadeem, Ming-Yen Ng, Ashish H. Shah, Edythe B. Tham, Judith Therrien, Andrew E. Warren, Isabelle F. Vonder Muhll, Alexander Van de Bruaene, Kenichiro Yamamura, Michael E. Farkouh, Rachel M. Wald
Summary: This study explored the relationship between pulmonary regurgitation and quality of life and health status in adults with Tetralogy of Fallot (TOF), and found that with advancing age, patients reported more problems in mobility and pain or discomfort. Factors associated with superior patient-reported outcomes include race, syndrome, employment, and left ventricular function, while being asymptomatic was found to have the greatest impact on quality of life and health status.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Oncology
Elena Parvez, Megan Chu, David Kirkwood, Aristithes Doumouras, Mark Levine, Jessica Bogach
Summary: This study compared the symptom burden between immigrant and long-term resident women undergoing breast cancer surgery in Ontario, Canada. The results showed that immigrant women had a higher burden of pain and other symptoms.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Medicine, General & Internal
Ethan Basch, Deborah Schrag, Sydney Henson, Jennifer Jansen, Brenda Ginos, Angela M. Stover, Philip Carr, Patricia A. Spears, Mattias Jonsson, Allison M. Deal, Antonia Bennett, Gita Thanarajasingam, Lauren J. Rogak, Bryce B. Reeve, Claire Snyder, Deborah Bruner, David Cella, Lisa A. Kottschade, Jane Perlmutter, Cindy Geoghegan, Cleo A. Samuel-Ryals, Barbara Given, Gina L. Mazza, Robert Miller, Jon F. Strasser, Dylan M. Zylla, Anna Weiss, Victoria S. Blinder, Amylou C. Dueck
Summary: The use of electronic PRO surveys to monitor symptoms in cancer patients led to statistically significant improvements in physical function, symptom control, and HRQOL at 3 months compared to usual care, with mean improvements of approximately 2.5 points on a 0-100 point scale.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Review
Oncology
Alexander Fabian, Justus Domschikowski, Markus Hoffmann, Oliver Weiner, Claudia Schmalz, Juergen Dunst, David Krug
Summary: This systematic review aims to assess the impact of palliative radiotherapy on patient-reported outcomes for head and neck cancer. It found that palliative radiotherapy may have a positive effect on health-related quality of life and symptom burden, but highlights the need for more studies focusing on patient-reported outcomes.
FRONTIERS IN ONCOLOGY
(2021)
Article
Surgery
Jordan M. Broekhuis, Chun Li, Hao Wei Chen, Natalia Chaves, Sarah Duncan, Betzamel Lopez, Anthony H. Maeda, Per-Olaf Hasselgren, Peter Mowschenson, Benjamin C. James
Summary: The study found that 16% of thyroid cancer patients reported financial burden and 50% reported psychological financial hardship. The research also revealed a significant correlation between financial burden and psychological financial hardship, as well as with sociodemographic data.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Medicine, General & Internal
Christopher J. D. Wallis, Alyson L. Mahar, Richard Choo, Sender Herschorn, Ronald T. Kodama, Prakesh S. Shah, Cyril Danjoux, Steven A. Narod, Robert K. Nam
BMJ-BRITISH MEDICAL JOURNAL
(2016)
Review
Medicine, General & Internal
Christopher J. D. Wallis, Alyson L. Mahar, Richard Choo, Sender Herschorn, Ronald T. Kodama, Prakesh S. Shah, Cyril Danjoux, Steven A. Narod, Robert K. Nam
BMJ-BRITISH MEDICAL JOURNAL
(2016)
Article
Oncology
Trevor D. Hamilton, Alyson L. Mahar, Barbara Haas, Kaitlyn Beyfuss, Calvin H. L. Law, Paul J. Karanicolas, Natalie G. Coburn, Julie Hallet
Review
Oncology
Alyson L. Mahar, Carolyn Compton, Susan Halabi, Kenneth R. Hess, Martin R. Weiser, Patti A. Groome
JOURNAL OF SURGICAL ONCOLOGY
(2017)
Article
Health Care Sciences & Services
Alyson L. Mahar, Yunni Jeong, Brandon Zagorski, Natalie Coburn
BMC HEALTH SERVICES RESEARCH
(2018)
Article
Oncology
Laura E. Davis, Lev D. Bubis, Alyson L. Mahar, Qing Li, Jonathan Sussman, Lesley Moody, Lisa Barbera, Claire M. B. Holloway, Natalie G. Coburn
EUROPEAN JOURNAL OF CANCER
(2018)
Review
Cardiac & Cardiovascular Systems
Vaibhav Gupta, Natalie Coburn, Biniam Kidane, Kenneth R. Hess, Carolyn Compton, Jolie Ringash, Gail Darling, Alyson L. Mahar
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Article
Gastroenterology & Hepatology
Madeline Lemke, Alyson Mahar, Paul J. Karanicolas, Natalie G. Coburn, Calvin H. L. Law, Julie Hallet
Article
Oncology
Melanie E. Tsang, Alyson L. Mahar, Guillaume Martel, Sean P. Cleary, Sulaiman Nanji, Jean-Francois Ouellet, Roberto Hernandez-Alejandro, Alice C. Wei, Julie Hallet
JOURNAL OF SURGICAL ONCOLOGY
(2018)
Article
Oncology
Yunni Jeong, Alyson L. Mahar, Natalie G. Coburn, Christopher J. Wallis, Raj Satkunasivam, Kaitlyn Beyfuss, Paul J. Karanicolas, Calvin H. L. Law, Julie Hallet
ANNALS OF SURGICAL ONCOLOGY
(2018)
Article
Public, Environmental & Occupational Health
Alyson L. Mahar, Brandon Zagorski, Daniel Kagedan, Matthew Dixon, Abraham El-Sedfy, Jovanka Vasilevska-Ristovska, Daniela Cortinovis, Corwyn Rowsell, Calvin Law, Lucy Helyer, Lawrence Paszat, Natalie Coburn
CANADIAN JOURNAL OF PUBLIC HEALTH-REVUE CANADIENNE DE SANTE PUBLIQUE
(2018)
Article
Psychiatry
Alyson L. Mahar, Alice B. Aiken, Heidi Cramm, Marlo Whitehead, Patti Groome, Paul Kurdyak
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
(2018)
Letter
Oncology
Alyson L. Mahar, Daniel J. Kagedan, Julie Hallet, Natalie G. Coburn
Article
Oncology
Alyson L. Mahar, Daniel J. Kagedan, Julie Hallet, Natalie G. Coburn