Ebselen inhibits the activity of acetylcholinesterase globular isoform G4 in vitro and attenuates scopolamine-induced amnesia in mice

Ebselen ameliorates β-amyloid pathology, tau pathology, and cognitive impairment in triple-transgenic Alzheimer’s disease mice

(2017) Yongli Xie et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Saffron (Crocus sativus L.) Tea Intake Prevents Learning/Memory Defects and Neurobiochemical Alterations Induced by Aflatoxin B1 Exposure in Adult Mice

(2017) Zacharoula I. Linardaki et al.   NEUROCHEMICAL RESEARCH

Ebselen, a useful tool for understanding cellular redox biology and a promising drug candidate for use in human diseases

(2016) Noriko Noguchi   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

(2016) Charles Masaki et al.   PSYCHOPHARMACOLOGY

A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

(2016) Andrea Wolf et al.   PLoS One

Hyperhomocysteinemia: Impact on Neurodegenerative Diseases

(2015) Meenakshi Sharma et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep and Emotional Processing in Humans

(2015) Nisha Singh et al.   NEUROPSYCHOPHARMACOLOGY

Cholinesterase inhibitors and add-on nutritional supplements in Alzheimer's disease

(2014) A. Rijpma et al.   AGEING RESEARCH REVIEWS

Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer’s disease

(2014) Zonghua Luo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibitory Effect of Ebselen on Cerebral Acetylcholinesterase Activity In Vitro: Kinetics and Reversibility of Inhibition

(2014) Franciele Martini et al.   CURRENT PHARMACEUTICAL DESIGN

Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice

(2014) Barbara Budzynska et al.   PSYCHOPHARMACOLOGY

Glutathione Peroxidase Mimic Ebselen Improves Glucose-Stimulated Insulin Secretion in Murine Islets

(2013) Xinhui Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

The early research and development of ebselen

(2013) Michael J. Parnham et al.   BIOCHEMICAL PHARMACOLOGY

Ebselen Treatment Prevents Islet Apoptosis, Maintains Intranuclear Pdx-1 and MafA Levels, and Preserves  -Cell Mass and Function in ZDF Rats

(2013) J. Mahadevan et al.   DIABETES

Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

(2013) Zonghua Luo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease

(2013) Chris G. Parsons et al.   NEUROTOXICITY RESEARCH

Protective effect ofCnestis ferrugineaand its active constituent on scopolamine-induced memory impairment in mice: A behavioral and biochemical study

(2013) Ismail O. Ishola et al.   PHARMACEUTICAL BIOLOGY

A safe lithium mimetic for bipolar disorder

(2013) Nisha Singh et al.   Nature Communications

Ebselen reduces hyperglycemia temporarily-induced by diazinon: A compound with insulin-mimetic properties

(2012) Michael D. Costa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer's disease

(2012) Carola Romberg et al.   NEUROBIOLOGY OF AGING

Subcortical atrophy and cognition: Sex effects in multiple sclerosis

(2012) M. M. Schoonheim et al.   NEUROLOGY

Cognitive Impairment in Huntington Disease: Diagnosis and Treatment

(2011) Jane S. Paulsen   Current Neurology and Neuroscience Reports

Genetic counseling and testing for Alzheimer disease: Joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors

(2011) Jill S Goldman et al.   GENETICS IN MEDICINE

The cholinergic system and hippocampal plasticity

(2010) Benjamin D. Drever et al.   BEHAVIOURAL BRAIN RESEARCH

Protein aggregation diseases: pathogenicity and therapeutic perspectives

(2010) Adriano Aguzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Cognitive enhancement by drugs in health and disease

(2010) Masud Husain et al.   TRENDS IN COGNITIVE SCIENCES

Effects of donepezil on amyloid-β and synapse density in the Tg2576 mouse model of Alzheimer's disease

(2009) Hongxin Dong et al.   BRAIN RESEARCH

Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells

(2009) Se-Jin Kim et al.   HEARING RESEARCH

Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease

(2009) Susan D Rountree et al.   Alzheimers Research & Therapy

Natural Products and their Derivatives as Cholinesterase Inhibitors in the Treatment of Neurodegenerative Disorders: An Update

(2008) Monica Loizzo et al.   CURRENT MEDICINAL CHEMISTRY

Pre-treatment with ebselen and vitamin E modulate acetylcholinesterase activity: interaction with demyelinating agents

(2008) Cinthia M. Mazzanti et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE