Cucurbitacin I induces pro-death autophagy in A549 cells via the ERK-mTOR-STAT3 signaling pathway

Quantifying autophagy: Measuring LC3 puncta and autolysosome formation in cells using multispectral imaging flow cytometry

(2017) Haley R. Pugsley   METHODS

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells

(2016) Guixin Ma et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

(2016) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

(2016) Francesca Vittoria Sbrana et al.   Stem Cell Reviews and Reports

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

(2016) Francesca Vittoria Sbrana et al.   Stem Cell Reviews and Reports

Autophagy promotes apoptosis of mesenchymal stem cells under inflammatory microenvironment

(2015) Shipeng Dang et al.   Stem Cell Research & Therapy

Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers

(2014) Sylvain Lefort et al.   Autophagy

Cucurbitacin I Induces Protective Autophagy in Glioblastomain Vitroandin Vivo

(2014) Guang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent Clinical Advances in Lung Cancer Management

(2014) David H. Johnson et al.   JOURNAL OF CLINICAL ONCOLOGY

Complex regulation of autophagy in cancer – Integrated approaches to discover the networks that hold a double-edged sword

(2013) János Kubisch et al.   SEMINARS IN CANCER BIOLOGY

Biological activities and potential molecular targets of cucurbitacins

(2012) Xiuping Chen et al.   ANTI-CANCER DRUGS

Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis

(2012) Tiejun Zhang et al.   Autophagy

Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway

(2012) Yajing Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

Suppression of growth of A549 lung cancer cells by waltonitone and its mechanisms of action

(2012) YI ZHANG et al.   ONCOLOGY REPORTS

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells

(2011) Jia-Ching Wu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Constitutive Activation of STAT3 by Curcurbitacin-I (JSI-124) Sensitized Human B-Leukemia Cells to Apoptosis

(2010) G. Ishdorj et al.   MOLECULAR CANCER THERAPEUTICS

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

(2009) Jie Li et al.   ANNALS OF SURGICAL ONCOLOGY

Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

(2009) N. H. Thoennissen et al.   CANCER RESEARCH

Signal Transducer and Activator of Transcription 3 (STAT3) Mediates Amino Acid Inhibition of Insulin Signaling through Serine 727 Phosphorylation

(2009) Jeong-Ho Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Cytotoxic Properties of Root Extract and Fruit Juice ofTrichosanthes cucumerina

(2009) Sumonthip Kongtun et al.   PLANTA MEDICA

Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway

(2008) Fernando J. Reyes-Zurita et al.   CANCER LETTERS

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer

(2008) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

(2008) G. Tang et al.   HUMAN MOLECULAR GENETICS