Ultrasound-triggered effects of the microbubbles coupled to GDNF- and Nurr1-loaded PEGylated liposomes in a rat model of Parkinson's disease

Newborn dopaminergic neurons are associated with the migration and differentiation of SVZ-derived neural progenitors in a 6-hydroxydopamin-injected mouse model

(2017) M.Q. Xie et al.   NEUROSCIENCE

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

(2016) Ian Mitchelle S. de Vera et al.   ACS Chemical Biology

Nurr1-Based Therapies for Parkinson's Disease

(2016) Jie Dong et al.   CNS Neuroscience & Therapeutics

Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression

(2016) Fanhua Meng et al.   Oncology Letters

Novel drug delivery liposomes targeted with a fully human anti-VEGF165 monoclonal antibody show superior antitumor efficacy in vivo

(2015) Chenyang Shi et al.   BIOMEDICINE & PHARMACOTHERAPY

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease

(2015) S.-M. Oh et al.   EMBO Molecular Medicine

Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment

(2015) Xiaobo Wei et al.   MOLECULAR NEUROBIOLOGY

Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease

(2015) Chun-Hyung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theranostic mRNA-loaded Microbubbles in the Lymphatics of Dogs: Implications for Drug Delivery

(2015) Heleen Dewitte et al.   Theranostics

Functional Neuroprotection and Efficient Regulation of GDNF Using Destabilizing Domains in a Rodent Model of Parkinson’s Disease

(2013) Luis Quintino et al.   MOLECULAR THERAPY

NURR1 in Parkinson disease—from pathogenesis to therapeutic potential

(2013) Mickael Decressac et al.   Nature Reviews Neurology

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

(2013) Elaine L. Pranski et al.   NEUROBIOLOGY OF DISEASE

Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s disease

(2013) X. Yue et al.   NEUROSCIENCE

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

Glial cell-line derived neurotrophic factor (GDNF) replacement attenuates motor impairments and nigrostriatal dopamine deficits in 12-month-old mice with a partial deletion of GDNF

(2013) Ofelia M. Littrell et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Regulated Expression of Lentivirus-Mediated GDNF in Human Bone Marrow-Derived Mesenchymal Stem Cells and Its Neuroprotection on Dopaminergic Cells In Vitro

(2013) Wei-Hua Yang et al.   PLoS One

Lung Surfactant Microbubbles Increase Lipophilic Drug Payload for Ultrasound-Targeted Delivery

(2013) Shashank R. Sirsi et al.   Theranostics

Efficient Catalytic Reduction of Hexavalent Chromium Using Palladium Nanoparticle-Immobilized Electrospun Polymer Nanofibers

(2012) Yunpeng Huang et al.   ACS Applied Materials & Interfaces

Riluzole neuroprotection in a parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation

(2012) Marica Carbone et al.   BMC NEUROSCIENCE

Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson’s disease: focus on levodopa/carbidopa/entacapone

(2012) Heinz Reichmann et al.   Expert Review of Neurotherapeutics

Targeted Delivery of GDNF through the Blood–Brain Barrier by MRI-Guided Focused Ultrasound

(2012) Feng Wang et al.   PLoS One

 -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons

(2012) M. Decressac et al.   Science Translational Medicine

Signaling of Glial Cell Line-Derived Neurotrophic Factor and Its Receptor GFRα1 Induce Nurr1 and Pitx3 to Promote Survival of Grafted Midbrain-Derived Neural Stem Cells in a Rat Model of Parkinson Disease

(2011) Zhinian Lei et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Identification of Bilateral Changes in TID1 Expression in the 6-OHDA Rat Model of Parkinson's Disease

(2011) Juliane Proft et al.   PLoS One

Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood–brain barrier

(2010) Ailing Fu et al.   BRAIN RESEARCH

Ultrasound-triggered release of materials entrapped in microbubble–liposome constructs: A tool for targeted drug delivery

(2010) Alexander L. Klibanov et al.   JOURNAL OF CONTROLLED RELEASE

The dopamine transporter is differentially regulated after dopaminergic lesion

(2010) Domingo Afonso-Oramas et al.   NEUROBIOLOGY OF DISEASE

Effects of a novel ultrasound contrast agent with long persistence on right ventricular pressure: Comparison with SonoVue

(2010) Ping Liu et al.   ULTRASONICS

Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats

(2009) Rinske Vlamings et al.   BRAIN RESEARCH

Comparison of Blood-Brain Barrier Transport of Glial-Derived Neurotrophic Factor (GDNF) and an IgG-GDNF Fusion Protein in the Rhesus Monkey

(2009) R. J. Boado et al.   DRUG METABOLISM AND DISPOSITION

Design and Evaluation of Doxorubicin-containing Microbubbles for Ultrasound-triggered Doxorubicin Delivery: Cytotoxicity and Mechanisms Involved

(2009) Ine Lentacker et al.   MOLECULAR THERAPY