Three-dimensional liver-derived extracellular matrix hydrogel promotes liver organoids function

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

(2017) Sabine U. Vorrink et al.   FASEB JOURNAL

Mechanically Oriented 3D Collagen Hydrogel for Directing Neurite Growth

(2017) Merav Antman-Passig et al.   TISSUE ENGINEERING PART A

Engineered Hydrogels in Cancer Therapy and Diagnosis

(2017) Mohammadmajid Sepantafar et al.   TRENDS IN BIOTECHNOLOGY

Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro

(2016) Sofia B. Leite et al.   BIOMATERIALS

Substrate stiffness and matrix composition coordinately control the differentiation of liver progenitor cells

(2016) Andreas P. Kourouklis et al.   BIOMATERIALS

Stem cells and injectable hydrogels: Synergistic therapeutics in myocardial repair

(2016) Mohammadmajid Sepantafar et al.   BIOTECHNOLOGY ADVANCES

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates

(2016) Volker M. Lauschke et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Solubilized liver extracellular matrix maintains primary rat hepatocyte phenotypein-vitro

(2016) Abigail E. Loneker et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Decellularized Liver Extracellular Matrix as Promising Tools for Transplantable Bioengineered Liver Promotes Hepatic Lineage Commitments of Induced Pluripotent Stem Cells

(2016) Kyung-Mee Park et al.   TISSUE ENGINEERING PART A

Recapitulating Cell–Cell Interactions for Organoid Construction – Are Biomaterials Dispensable?

(2016) Andrew C.A. Wan   TRENDS IN BIOTECHNOLOGY

Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation

(2015) Takanori Takebe et al.   Cell Stem Cell

Cell therapy for liver disease: From liver transplantation to cell factory

(2015) Stuart J. Forbes et al.   JOURNAL OF HEPATOLOGY

Three-dimensional co-culture of human hepatocytes and mesenchymal stem cells: improved functionality in long-term bioreactor cultures

(2015) Sofia P. Rebelo et al.   Journal of Tissue Engineering and Regenerative Medicine

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

(2015) Timothy J. Keane et al.   METHODS

Manipulating hepatocellular carcinoma cell fate in orthogonally cross-linked hydrogels

(2014) Tsai-Yu Lin et al.   BIOMATERIALS

Engineering cell matrix interactions in assembled polyelectrolyte fiber hydrogels for mesenchymal stem cell chondrogenesis

(2014) Deepak Raghothaman et al.   BIOMATERIALS

Advances in tissue engineering through stem cell-based co-culture

(2014) Nikolaos K. Paschos et al.   Journal of Tissue Engineering and Regenerative Medicine

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions

(2014) Benjamin Struecker et al.   Journal of Tissue Engineering and Regenerative Medicine

Liver Extracellular Matrix Providing Dual Functions of Two-Dimensional Substrate Coating and Three-Dimensional Injectable Hydrogel Platform for Liver Tissue Engineering

(2013) Jung Seung Lee et al.   BIOMACROMOLECULES

Solubilized matrix derived from decellularized liver as a growth factor-immobilizable scaffold for hepatocyte culture

(2013) Shintaro Nakamura et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Perfusion decellularization of human and porcine lungs: Bringing the matrix to clinical scale

(2013) Sarah Elizabeth Gilpin et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

An efficient method for decellularization of the rat liver

(2013) Ming Xin Pan et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Metre-long cell-laden microfibres exhibit tissue morphologies and functions

(2013) Hiroaki Onoe et al.   NATURE MATERIALS

Injectable extracellular matrix derived hydrogel provides a platform for enhanced retention and delivery of a heparin-binding growth factor

(2012) Sonya B. Seif-Naraghi et al.   Acta Biomaterialia

The differentiation of MSCs into functional hepatocyte-like cells in a liver biomatrix scaffold and their transplantation into liver-fibrotic mice

(2012) Ru Ji et al.   BIOMATERIALS

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy

(2012) Fei Yi et al.   Protein & Cell

Three-dimensional culture of hepatocytes on porcine liver tissue-derived extracellular matrix

(2011) Ren Lang et al.   BIOMATERIALS

The use of whole organ decellularization for the generation of a vascularized liver organoid

(2010) Pedro M. Baptista et al.   HEPATOLOGY

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

(2010) Basak E Uygun et al.   NATURE MEDICINE

Regeneration and orthotopic transplantation of a bioartificial lung

(2010) Harald C Ott et al.   NATURE MEDICINE

Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening

(2010) Melissa A. Baxter et al.   Stem Cell Research

Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering

(2009) Jennifer M. Singelyn et al.   BIOMATERIALS

Maintenance of Human Hepatocyte Function In Vitro by Liver-Derived Extracellular Matrix Gels

(2009) Tiffany L. Sellaro et al.   TISSUE ENGINEERING PART A

Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix

(2008) Donald O. Freytes et al.   BIOMATERIALS

A new technique for primary hepatocyte expansion in vitro

(2008) Cheul H. Cho et al.   BIOTECHNOLOGY AND BIOENGINEERING

Hepatocyte transplantation: waiting for stem cells

(2008) Dhivya Haridass et al.   Current Opinion in Organ Transplantation

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

(2008) Harald C Ott et al.   NATURE MEDICINE