Abscisic acid – an anti-angiogenic phytohormone that modulates the phenotypical plasticity of endothelial cells and macrophages

ABA Represses the Expression of Cell Cycle Genes and May Modulate the Development of Endodormancy in Grapevine Buds

(2017) Ricardo Vergara et al.   Frontiers in Plant Science

PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy

(2017) Sha Gao et al.   Scientific Reports

Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy

(2017) Sangmi Lee et al.   Scientific Reports

Role of the proteome in phytohormonal signaling

(2016) Martin Černý et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Tissue resident macrophages: Key players in the pathogenesis of type 2 diabetes and its complications

(2016) Reza Meshkani et al.   CLINICA CHIMICA ACTA

Abscisic Acid: A Phytohormone and Mammalian Cytokine as Novel Pharmacon with Potential for Future Development into Clinical Applications

(2016) Priya Sakthivel et al.   CURRENT MEDICINAL CHEMISTRY

Carbohydrate-binding protein CLEC14A regulates VEGFR-2– and VEGFR-3–dependent signals during angiogenesis and lymphangiogenesis

(2016) Sungwoon Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

(2016) Ido Amit et al.   NATURE IMMUNOLOGY

Regulating the regulators of angiogenesis by CCN1 and taking it up a Notch

(2016) Brahim Chaqour   Journal of Cell Communication and Signaling

Pharmacokinetic and Pharmacodynamic Properties of Anti-VEGF Drugs After Intravitreal Injection

(2015) Francesco Semeraro et al.   CURRENT DRUG METABOLISM

The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling

(2015) H. Chintala et al.   DEVELOPMENT

Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene TargetCCN1in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia

(2015) Lulu Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathophysiology and Mechanisms of Severe Retinopathy of Prematurity

(2015) M. Elizabeth Hartnett   OPHTHALMOLOGY

Molecular and epigenetic basis of macrophage polarized activation

(2015) Chiara Porta et al.   SEMINARS IN IMMUNOLOGY

IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis

(2015) Rei Nakamura et al.   Nature Communications

A Systematic Review and Meta-Analysis on the Safety of Vascular Endothelial Growth Factor (VEGF) Inhibitors for the Treatment of Retinopathy of Prematurity

(2015) Laura Pertl et al.   PLoS One

Abscisic acid perception and signaling: structural mechanisms and applications

(2014) Ley Moy Ng et al.   ACTA PHARMACOLOGICA SINICA

Honokiol inhibits pathological retinal neovascularization in oxygen-induced retinopathy mouse model

(2013) Divya Teja Vavilala et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of oxygen on the development and severity of retinopathy of prematurity

(2013) M. Elizabeth Hartnett et al.   JOURNAL OF AAPOS

Endothelial Cell-specific Chemotaxis Receptor (ECSCR) Enhances Vascular Endothelial Growth Factor (VEGF) Receptor-2/Kinase Insert Domain Receptor (KDR) Activation and Promotes Proteolysis of Internalized KDR

(2013) Sreenivasulu Kilari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

(2013) Sara Zanivan et al.   MOLECULAR & CELLULAR PROTEOMICS

Cysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapy

(2013) Lulu Yan et al.   Journal of Cell Communication and Signaling

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

(2012) M. Suzuki et al.   JOURNAL OF CELL SCIENCE

Dietary abscisic acid ameliorates influenza-virus-associated disease and pulmonary immunopathology through a PPARγ-dependent mechanism

(2012) Raquel Hontecillas et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Shear stress, tip cells and regulators of endothelial migration

(2011) Xiaodong Zhuang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Matricellular Protein Cysteine-rich Protein 61 (CCN1/Cyr61) Enhances Physiological Adaptation of Retinal Vessels and Reduces Pathological Neovascularization Associated with Ischemic Retinopathy

(2011) Adeel Hasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes

(2011) Santina Bruzzone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A

(2011) M Mura et al.   ONCOGENE

A Computational Tool for Quantitative Analysis of Vascular Networks

(2011) Enrique Zudaire et al.   PLoS One

Systemic and Ocular Safety of Intravitreal Anti-VEGF Therapies for Ocular Neovascular Disease

(2011) Michael Tolentino   SURVEY OF OPHTHALMOLOGY

Differential Macrophage Polarization Promotes Tissue Remodeling and Repair in a Model of Ischemic Retinopathy

(2011) Valentina Marchetti et al.   Scientific Reports

Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability

(2011) Kenichi Kimoto et al.   Journal of Ophthalmology

Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity

(2010) A. Verma et al.   BLOOD

von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina

(2010) T. Kurihara et al.   DEVELOPMENT

Abscisic Acid Regulates Inflammation via Ligand-binding Domain-independent Activation of Peroxisome Proliferator-activated Receptor γ

(2010) Josep Bassaganya-Riera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABC transporter AtABCG25 is involved in abscisic acid transport and responses

(2010) T. Kuromori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computer-aided quantification of retinal neovascularization

(2009) A. Stahl et al.   ANGIOGENESIS

Oxygen-Induced Retinopathy in Mice: Amplification by Neonatal IGF-I Deficit and Attenuation by IGF-I Administration

(2009) Sophie Vanhaesebrouck et al.   PEDIATRIC RESEARCH

ECSM2, An Endothelial Specific Filamin A Binding Protein That Mediates Chemotaxis

(2008) Laura-Jane Armstrong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Abscisic Acid Is an Endogenous Stimulator of Insulin Release from Human Pancreatic Islets with Cyclic ADP Ribose as Second Messenger

(2008) Santina Bruzzone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

(2008) Esther J. Kuiper et al.   PLoS One

Loss of PPARγ in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue

(2007) Amir J. Guri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY