Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation

Three-Dimensional Structures of Full-Length, Membrane-Embedded Human αIIbβ3 Integrin Complexes

(2016) Xiao-Ping Xu et al.   BIOPHYSICAL JOURNAL

A Guide to Fluorescent Protein FRET Pairs

(2016) Bryce Bajar et al.   SENSORS

The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities

(2015) Samuel Genheden et al.   Expert Opinion on Drug Discovery

Anchorage-dependent binding of integrin I-domain to adhesion ligands

(2015) Xin Fu et al.   JOURNAL OF MOLECULAR RECOGNITION

Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells

(2015) Noriko Takahashi et al.   Nature Communications

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers

(2014) B. G. Pierce et al.   BIOINFORMATICS

Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex

(2014) W. Zhang et al.   BLOOD

Distinct Chemokine Signaling Regulates Integrin Ligand Specificity to Dictate Tissue-Specific Lymphocyte Homing

(2014) Hao Sun et al.   DEVELOPMENTAL CELL

Complete integrin headpiece opening in eight steps

(2013) Jieqing Zhu et al.   JOURNAL OF CELL BIOLOGY

The PSGL-1–L-selectin signaling complex regulates neutrophil adhesion under flow

(2013) Anika Stadtmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Structural specializations of α4β7, an integrin that mediates rolling adhesion

(2012) Yamei Yu et al.   JOURNAL OF CELL BIOLOGY

The regulation of integrin function by divalent cations

(2012) Kun Zhang et al.   Cell Adhesion & Migration

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

The CC′ and DE Loops in Ig Domains 1 and 2 of MAdCAM-1 Play Different Roles in MAdCAM-1 Binding to Low- and High-affinity Integrin α4β7

(2011) Hao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Closed headpiece of integrin  IIb 3 and its complex with an  IIb 3-specific antagonist that does not induce opening

(2010) J. Zhu et al.   BLOOD

Focal adhesions are sites of integrin extension

(2010) Janet A. Askari et al.   JOURNAL OF CELL BIOLOGY

A mechanically stabilized receptor–ligand flex-bond important in the vasculature

(2010) Jongseong Kim et al.   NATURE

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Cation-  interaction regulates ligand-binding affinity and signaling of integrin  4 7

(2010) Y. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

(2009) Jian-Ping Xiong et al.   JOURNAL OF CELL BIOLOGY

Linking integrin conformation to function

(2009) J. A. Askari et al.   JOURNAL OF CELL SCIENCE

Activated Integrin VLA-4 Localizes to the Lamellipodia and Mediates T Cell Migration on VCAM-1

(2009) Y.-M. Hyun et al.   JOURNAL OF IMMUNOLOGY

Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

(2009) S. Lindert et al.   JOURNAL OF VIROLOGY

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module

(2009) Matteo Bolomini-Vittori et al.   NATURE IMMUNOLOGY

Single-molecule mechanics: New insights from the escape-over-a-barrier problem

(2009) O. K. Dudko   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replacing a Lectin Domain Residue in L-selectin Enhances Binding to P-selectin Glycoprotein Ligand-1 but Not to 6-Sulfo-sialyl Lewis x

(2008) Arkadiusz G. Klopocki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-cell force spectroscopy

(2008) J. Helenius et al.   JOURNAL OF CELL SCIENCE

Integrin αIIbβ3 in a Membrane Environment Remains the Same Height after Mn2+ Activation when Observed by Cryoelectron Tomography

(2008) Feng Ye et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL