Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

(2017) Benjamin H. Mullin et al.   HUMAN MOLECULAR GENETICS

Reflecting on Some Discoveries of 40 Years and Their Outcomes

(2017) T John Martin   JOURNAL OF BONE AND MINERAL RESEARCH

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

(2017) John P Kemp et al.   NATURE GENETICS

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

(2016) Benjamin H. Mullin et al.   BMC GENOMICS

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Fast and efficient QTL mapper for thousands of molecular phenotypes

(2015) Halit Ongen et al.   BIOINFORMATICS

GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approach

(2015) Ellen M. Schmidt et al.   BIOINFORMATICS

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

(2015) Hou‐Feng Zheng et al.   NATURE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Efficient haplotype matching and storage using the positional Burrows-Wheeler transform (PBWT)

(2014) R. Durbin   BIOINFORMATICS

The Cdc42 Guanine Nucleotide Exchange Factor FGD6 Coordinates Cell Polarity and Endosomal Membrane Recycling in Osteoclasts

(2014) Charlotte Steenblock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of ARHGEF3 and RHOA Knockdown on ACTA2 and Other Genes in Osteoblasts and Osteoclasts

(2014) Benjamin H. Mullin et al.   PLoS One

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Skeletal Manifestations of Treatment of Breast Cancer

(2013) Palak Choksi et al.   Current Osteoporosis Reports

Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix

(2012) Sjur Reppe et al.   BONE

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration

(2012) Darren E. Casteel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees

(2012) C.-H. Chou et al.   OSTEOARTHRITIS AND CARTILAGE

Significant Association between Common Polymorphisms in the Aromatase Gene CYP19A1 and Bone Mineral Density in Postmenopausal Women

(2011) B. H. Mullin et al.   CALCIFIED TISSUE INTERNATIONAL

Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by  -Catenin

(2011) W. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Evidence for an interaction between calcium intake and physical activity on changes in bone mineral density

(2010) Bonny L. Specker   JOURNAL OF BONE AND MINERAL RESEARCH

Heritable and life-style determinants of bone mineral density

(2010) Elizabeth A. Krall et al.   JOURNAL OF BONE AND MINERAL RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis

(2009) Ben H. Mullin et al.   BONE

Population genomics in a disease targeted primary cell model

(2009) E. Grundberg et al.   GENOME RESEARCH

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study

(2008) JB Richards et al.   LANCET