Article
Multidisciplinary Sciences
Daniel Santarem, Isabel Machado, Jaime Sampaio, Catarina Abrantes
Summary: The aim of this study was to assess the effect of muscle contraction type on SmO2 during a back squat exercise. The results showed that dynamic contraction resulted in lower minimum SmO2, indicating a larger oxygen supply-consumption gap due to higher muscle activation demands.
Article
Chemistry, Multidisciplinary
Pat R. Vehrs, Chase Blazzard, Hannah C. Hart, Nicole Kasper, Ryan Lacey, Daniela Lopez, Shay Richards, Dennis L. Eggett
Summary: This study measured arterial occlusion pressure (AOP) in the dominant and non-dominant legs of males and females using different cuff inflation protocols. The results showed no significant differences in AOP within or between the legs, or between sexes. AOP measurements were highly reliable, and the choice of cuff inflation protocol was a matter of personal preference. It is important to measure AOP in both limbs to ensure safe and effective use of blood flow restriction (BFR) during exercise.
APPLIED SCIENCES-BASEL
(2023)
Article
Physiology
Robert Solsona, Hugues Berthelot, Fabio Borrani, Anthony M. J. Sanchez
Summary: The study found that sprint interval exercises (SIT) with gravity-induced blood flow restriction (G-BFR) led to lower mechanical, cardiorespiratory, and skeletal muscle oxygenation responses compared to other conditions. Training with BFR at 60% occlusive pressure (BFR60) resulted in higher blood accumulation in working muscles, potentially affecting cellular stress. Both hypoxia (HYP) and G-BFR induced local hypoxia, with G-BFR showing higher levels during both exercise bouts and recovery periods.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Physiology
Damir Zubac, Ante Obad, Daniela Supe-Domic, Ana Bosnjak, Mirela Zec, Vladimir Ivancev, Zoran Valic
Summary: The role of splenic emptying in oxygen transport during aerobic exercise is still debated. This study compared spleen volume changes between aerobically trained and untrained individuals during exercise and investigated the relationship with erythrocyte release and oxygen uptake parameters.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Orthopedics
Ryan J. Wortman, Symone M. Brown, Ian Savage-Elliott, Zachary J. Finley, Mary K. Mulcahey
Summary: The study indicates that blood flow restriction (BFR) training can improve strength, muscle size, and markers of sports performance in healthy athletes. Combining traditional resistance training with BFR may help athletes maximize athletic performance and maintain good health. Further research is needed to determine the optimal occlusive pressure for maximizing training improvements.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Article
Physiology
Robert Solsona, Romeo Deriaz, Fabio Borrani, Anthony M. J. Sanchez
Summary: This study compared muscle deoxygenation and reoxygenation kinetics during a sprint interval protocol under four different modalities. It found that reoxygenation was delayed in the blood flow restriction condition, and reoxygenation was slower in the gravity-induced blood flow restriction condition.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Neurosciences
Rebecca L. Scalzo, Irene E. Schauer, Deirdre Rafferty, Leslie A. Knaub, Nina Kvaratskhelia, Taro Kaelix Johnson, Gregory B. Pott, Layla A. Abushamat, Mary O. Whipple, Amy G. Huebschmann, Melanie Cree-Green, Jane E. B. Reusch, Judith G. Regensteiner
Summary: The study showed that single-leg exercise training can improve impaired skeletal muscle oxidative flux in people with type 2 diabetes, leading to increased skeletal muscle vasculature and oxygen delivery efficiency. This type of training is effective in improving cardiorespiratory fitness in individuals with type 2 diabetes.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Sport Sciences
Jefferson da Silva Novaes, Luiz Guilherme da Silva Telles, Estevao Rios Monteiro, Gleisson da Silva Araujo, Jakob L. Vingren, Patricia Silva Panza, Victor Machado Reis, Mateus Camaroti Laterza, Jeferson Macedo Vianna
Summary: The study showed that ischemic preconditioning significantly increased the number of repetitions and total volume in resistance training, but did not have a significant effect on rating of perceived exertion. Therefore, performing IPC before RE may help improve muscle performance and could be an important recommendation for athletic populations.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Masashi Ichinose, Mikie Nakabayashi, Yumie Ono
Summary: This study demonstrates that single muscle contractions induce rapid, intensity-dependent hyperemia within the contracted skeletal muscle microvasculature in humans, showing different characteristics compared to responses in the upstream conduit artery. Through the use of diffuse correlation spectroscopy and Doppler ultrasound, the magnitude and time course of the contraction-induced rapid hyperemia and vasodilatory responses within skeletal muscle microvessels significantly differ from those in the conduit artery.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Clinical Neurology
Orna Gera, Efrat Shavit-Stein, Taly Amichai, Vera Nikitin, Merav Ben David, Lior Greenbaum, Joab Chapman, Amir Dori
Summary: Post-exercise intramuscular blood flow is reduced in patients with polyneuropathy due to Charcot-Marie-Tooth disease type 1 (CMT1), and this reduction is present in both impaired distal and minimally affected proximal muscles, correlating with muscle strength, disease severity, and age.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Sport Sciences
Andre L. Teixeira, Ayesha Gangat, Julian C. C. Bommarito, Jamie F. F. Burr, Philip J. J. Millar
Summary: Ischemic preconditioning has a sex-specific effect on functional sympatholysis, which may contribute to the beneficial effects of ischemic preconditioning on exercise performance in humans.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Nutrition & Dietetics
Rafael A. Azevedo, Delbar Jazayeri, Samuel T. Yeung, Rojan Khoshreza, Guillaume Y. Millet, Juan Murias, Saied J. Aboodarda
Summary: Experiencing pain in one leg can decrease exercise tolerance and neuromuscular fatigue development in the contralateral leg. However, the effects of nonlocal experimental pain induced by blood flow occlusion on corticospinal modulation remain unknown. This study found that 25% maximal voluntary contraction (25%IMVC) duration was the shortest during blood flow occlusion, and the decline in maximal voluntary contraction was smaller compared to cycling exercise, indicating that pain reduces exercise performance. Additionally, transcranial magnetic stimulations revealed the modulation of the nervous system in response to pain stimulation.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Multidisciplinary Sciences
Ofer Shamni, Hilbert Grievink, Netanel Kolevzon, Seweryn Krajewski, Lukasz Steczek, Ella Meltzer, Shimon Yitshak, Eyal Mishani, Galith Abourbeh
Summary: The study aimed to increase the clinical applicability of PET-MPI by designing and synthesizing fluorinated ammonium salt derivatives and quinolinium salt analogs. Results showed that fluorinated DMDPA derivatives exhibited lower heart/liver radioactivity uptake ratios, while radiolabeled quinolinium salt derivatives demonstrated improved heart/liver ratios and clear visualization of the left ventricle myocardium. Renal clearance was the major route of elimination, with [F-18]FEtQ showing the best images among the fluorinated quaternary ammonium salts tested. Further studies are needed to elucidate the underlying mechanism of its cardiac uptake.
SCIENTIFIC REPORTS
(2021)
Article
Physiology
Michal Wilk, Michal Krzysztofik, Jakub Jarosz, Pawel Krol, Katarzyna Leznicka, Adam Zajac, Petr Stastny, Gregory C. Bogdanis
Summary: This study found that using ischemic conditioning before each set of the bench press exercise can increase power output and bar velocity, potentially serving as a performance-enhancing stimulus during explosive resistance training.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Piotr Kaszczewski, Michal Elwertowski, Jerzy Leszczynski, Tomasz Ostrowski, Joanna Kaszczewska, Zbigniew Galazka
Summary: This study explores the changes in blood flow volume in carotid artery occlusion (CAO) patients and finds that volumetric flow compensation may play an important predictive role in these patients.
Review
Food Science & Technology
Thiago Silveira Alvares, Gustavo Vieira de Oliveira, Monica Volino-Souza, Carlos Adam Conte-Junior, Juan Manuel Murias
Summary: Dietary nitrate ingestion has a positive effect on muscular strength and muscular endurance, with a more significant impact observed during isometric and isotonic contractions. Dosage, frequency of ingestion, training level, muscle group, and type of contraction do not appear to significantly affect the outcomes. Further experimental research is needed to explore this topic.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Cristina Rezende, Gustavo Vieira de Oliveira, Monica Volino-Souza, Patricia Castro, Juan Manuel Murias, Thiago Silveira Alvares
Summary: The study showed that turmeric supplementation could improve cerebral oxygenation and blood volume during dynamic handgrip exercise in older males and females. Changes in heart rate and blood pressure were not significant. The findings suggest the potential of curcumin as an intervention for improving cerebral oxygenation and blood volume in older individuals.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2022)
Article
Physiology
Rafael de Almeida Azevedo, Daniel A. Keir, Jonas Forot, Danilo Iannetta, Guillaume Y. Millet, Juan M. Murias
Summary: This study investigates the relationship between the development of slow component of oxygen uptake and muscle fatigue, finding that they are correlated in a time- and intensity-dependent manner. The results suggest that the slow component of oxygen uptake may depend on muscle fatigue, even if the mechanisms of reduced contractile function differ among intensities.
Article
Physiology
Rafael de Almeida Azevedo, Jonas Forot, Guillaume Y. Millet, Juan M. Murias
Summary: This study investigated the relationship between pulmonary oxygen uptake and muscle oxygen uptake in females and males during cycling exercise at different intensities. The results showed a correlation between the two variables regardless of exercise intensity and sex of the participants.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Sport Sciences
Daniel A. Keir, Danilo Iannetta, Felipe Mattioni Maturana, John M. Kowalchuk, Juan M. Murias
Summary: This article highlights the importance of non-invasive identification of lactate threshold and respiratory compensation point during incremental exercise through pulmonary gas exchange and ventilatory variables. It also provides practical strategies for explaining the physiological mechanisms, identifying thresholds, and addressing related issues, as well as an online tool for practice and data analysis.
Article
Nutrition & Dietetics
Y. B. Somani, R. N. Soares, J. Gosalia, J. M. Delgado, M. Flanagan, S. Basu, D. B. Kim-Shapiro, J. M. Murias, D. N. Proctor
Summary: The onset of menopause and changes to ovarian hormones often lead to endothelial dysfunction in women. A study showed that acute dietary nitrate supplementation can improve endothelial function and reduce the magnitude of endothelial dysfunction caused by ischemia-reperfusion injury in healthy, early postmenopausal women.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Nutrition & Dietetics
Rafael A. Azevedo, Delbar Jazayeri, Samuel T. Yeung, Rojan Khoshreza, Guillaume Y. Millet, Juan Murias, Saied J. Aboodarda
Summary: Experiencing pain in one leg can decrease exercise tolerance and neuromuscular fatigue development in the contralateral leg. However, the effects of nonlocal experimental pain induced by blood flow occlusion on corticospinal modulation remain unknown. This study found that 25% maximal voluntary contraction (25%IMVC) duration was the shortest during blood flow occlusion, and the decline in maximal voluntary contraction was smaller compared to cycling exercise, indicating that pain reduces exercise performance. Additionally, transcranial magnetic stimulations revealed the modulation of the nervous system in response to pain stimulation.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Geriatrics & Gerontology
Danilo Iannetta, Erin Calaine Inglis, Felipe Mattioni Maturana, Giorgia Spigolon, Silvia Pogliaghi, Juan M. Murias
Summary: This study evaluated the effects of acute sprint interval training (SIT) on aerobic function in older inactive adults compared to their young counterparts. The results showed that SIT can acutely improve aerobic function by speeding the rate of adjustment of oxidative phosphorylation, especially in older adults. However, these beneficial effects are only maintained when the volume of SIT is maximized.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Physiology
Danilo Iannetta, Jenny Zhang, Juan M. Murias, Saied Jalal Aboodarda
Summary: This study evaluated the extent of peripheral and central fatigue, and corresponding perceptual attributes, at task failure following cycling within different exercise intensity domains. The findings demonstrate that the extent of peripheral fatigue is highly domain-specific, whereas the extent of central fatigue is not. Sensations such as fatigue, pain, and dyspnea demonstrated intensity domain specificity and might have contributed to reaching maximal levels of perceived effort and, thus, task failure.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Austin T. Beever, Andrea Y. Zhuang, Saied Jalal Aboodarda, Juan M. Murias, Martin J. MacInnis
Summary: Hypoxia has a negative impact on aerobic exercise, but exercise testing in hypoxic conditions has not been extensively studied. This research investigated the effects of simulated altitude on gas exchange threshold, respiratory compensation point, and maximal oxygen uptake. The findings suggest that mild simulated altitude affects maximal oxygen uptake and peak power output significantly, while gas exchange threshold and respiratory compensation point remain unchanged. Moderate altitude decreases all four variables.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Physiology
Hilkka Kontro, Craig Bertagnolli, Juan M. Murias, Martin J. MacInnis
Summary: The study found that an elevated COHb concentration intensified physiological responses to exercise at the MLSS and reduced the MLSS in trained individuals. Lower effective [Hb] due to CO inhalation decreased V?O2peak and MLSS performance, with higher aerobic fitness associated with greater impairments.
EXPERIMENTAL PHYSIOLOGY
(2022)
Article
Education, Scientific Disciplines
Serena Trang, Felipe Mattioni Maturana, Juan M. Murias, Michael R. Herbert, Daniel A. Keir
Summary: In exercise physiology, laboratory components are crucial for applying theoretical concepts to personal exercise experiences and introducing data collection and analysis. The gas exchange threshold (GET) and the respiratory compensation point (RCP) are key exercise thresholds that require proper identification. However, the processing and preparation of data have been time-consuming and challenging for students. This article presents a blended laboratory model featuring the Exercise Thresholds App, which provides immediate feedback and eliminates the need for data postprocessing, allowing students to practice threshold identification skills.
ADVANCES IN PHYSIOLOGY EDUCATION
(2023)
Article
Physiology
Rafael de Almeida Azevedo, Pablo R. Fleitas-Paniagua, Mackenzie Trpcic, Danilo Iannetta, Guillaume Y. Millet, Juan M. Murias
Summary: The aim of this study is to investigate the effects of different ramp-incremental (RI) slopes on fatigability and recovery in females and males. The results showed that gender had no significant effect on performance fatigability and recovery, and different RI slopes did not alter the level of performance fatigability at task failure.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Pablo R. Fleitas-Paniagua, Rafael de Almeida Azevedo, Mackenzie Trpcic, Juan M. Murias, Bruce Rogers
Summary: Detrended fluctuation analysis (DFA a1), an index of heart rate variability (HRV), has been of interest as a surrogate marker for exercise intensity boundaries. This report examined the behavior of heart rate variability thresholds (HRVT) across different ramp incremental slopes. The study found that the cycling ramp slope did not have a significant effect on HRVT1 and HRVT2 in terms of heart rate (HR) or VO2.
PHYSIOLOGICAL REPORTS
(2023)
Article
Physiology
Alessandro Moura Zagatto, Vithor Hugo Fialho Lopes, Yago Medeiros Dutra, Rodrigo Araujo Bonetti de Poli, Eimear Dolan, Letizia Rasica, Juan M. Murias, Paulo Henrique Silva Marques de Azevedo
Summary: This study aimed to investigate the effects of sodium bicarbonate (NaHCO3) ingestion on constant load cycling performance and neuromuscular fatigue. The results showed that NaHCO3 ingestion did not affect performance or indicators of neuromuscular fatigue. However, participants performed better when they were informed that they were ingesting an ergogenic supplement, suggesting a placebo effect may contribute to the apparent ergogenic effect of NaHCO3.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)