Cationic amphiphilic bolaamphiphile-based delivery of antisense oligonucleotides provides a potentially microbiome sparing treatment for C. difficile

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

(2018) L Clifford McDonald et al.   CLINICAL INFECTIOUS DISEASES

Antibiotic Treatments for Clostridium difficile Infection Are Associated with Distinct Bacterial and Fungal Community Structures

(2018) Regina Lamendella et al.   mSphere

Clostridium difficile Colonizes Alternative Nutrient Niches during Infection across Distinct Murine Gut Microbiomes

(2017) Matthew L. Jenior et al.   mSystems

Antimicrobial Nanoplexes meet Model Bacterial Membranes: the key role of Cardiolipin

(2017) Alejandro Marín-Menéndez et al.   Scientific Reports

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile

(2016) John Hegarty et al.   International Journal of Nanomedicine

Antimicrobial activity of antisense peptide–peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms

(2016) Taketo Otsuka et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

(2016) Dilay Hazal Ayhan et al.   PLOS BIOLOGY

Clostridium difficile Infection

(2015) Daniel A. Leffler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non-C. difficile-Associated Diarrhea from Healthy Controls

(2014) A. M. Schubert et al.   mBio

Safety Analysis of Fidaxomicin in Comparison With Oral Vancomycin for Clostridium difficile Infections

(2012) K. Weiss et al.   CLINICAL INFECTIOUS DISEASES

Predictors of First Recurrence of Clostridium difficile Infection: Implications for Initial Management

(2012) D. W. Eyre et al.   CLINICAL INFECTIOUS DISEASES

Predicting Recurrence of C. difficile Colitis Using Bacterial Virulence Factors: Binary Toxin Is the Key

(2012) David B. Stewart et al.   JOURNAL OF GASTROINTESTINAL SURGERY

From Serendipity to Mitochondria-Targeted Nanocarriers

(2011) Volkmar Weissig   PHARMACEUTICAL RESEARCH

Cardiolipin membrane domains in prokaryotes and eukaryotes

(2009) Eugenia Mileykovskaya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid domains in bacterial membranes and the action of antimicrobial agents

(2008) Richard M. Epand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Vancomycin for the Treatment ofClostridium difficileInfection: For Whom Is This Expensive Bullet Really Magic?

(2008) Jacques Pepin   CLINICAL INFECTIOUS DISEASES