标题
Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer’s Disease
作者
关键词
-
出版物
JOURNAL OF ALZHEIMERS DISEASE
Volume 61, Issue 3, Pages 843-866
出版商
IOS Press
发表日期
2018-01-10
DOI
10.3233/jad-170512
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease
- (2017) Chandra Bhushan Mishra et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Curcumin regulates insulin pathways and glucose metabolism in the brains of APPswe/PS1dE9 mice
- (2017) Pengwen Wang et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Novel Curcumin loaded nanoparticles engineered for Blood-Brain Barrier crossing and able to disrupt Abeta aggregates
- (2017) Ruozi Barbara et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Modulation in the conformational and stability attributes of the Alzheimer’s disease associated amyloid-beta mutants and their favorable stabilization by curcumin: molecular dynamics simulation analysis
- (2017) Manika Awasthi et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Surface plasmon resonance biosensors for simultaneous monitoring of amyloid-beta oligomers and fibrils and screening of select modulators
- (2016) Xinyao Yi et al. ANALYST
- Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors
- (2016) Michiaki Okuda et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Neuroprotective Role of Natural Polyphenols
- (2016) Carmela Spagnuolo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Downstream modulation of extrinsic apoptotic pathway in streptozotocin-induced Alzheimer's dementia in rats: Erythropoietin versus curcumin
- (2016) Doaa M. Samy et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A comparative study of dietary curcumin, nanocurcumin, and other classical amyloid-binding dyes for labeling and imaging of amyloid plaques in brain tissue of 5×-familial Alzheimer’s disease mice
- (2016) Panchanan Maiti et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Effects of curcumin on synapses in APPswe/PS1dE9 mice
- (2016) Yingkun He et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Curcumin ameliorates insulin signalling pathway in brain of Alzheimer’s disease transgenic mice
- (2016) Hui-li Feng et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1–42-injected mice
- (2016) Yanqiang Zhong et al. International Journal of Nanomedicine
- Anti-arrhythmic Medication Propafenone a Potential Drug for Alzheimer’s Disease Inhibiting Aggregation of Aβ: In Silico and in Vitro Studies
- (2016) Son Tung Ngo et al. Journal of Chemical Information and Modeling
- Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease
- (2016) P Hemachandra Reddy et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Development of a neuroprotective potential algorithm for medicinal plants
- (2016) Weixi Liu et al. NEUROCHEMISTRY INTERNATIONAL
- Amyloid binding properties of curcumin analogues in Alzheimer’s disease postmortem brain tissue
- (2016) Emma R. Veldman et al. NEUROSCIENCE LETTERS
- Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction
- (2016) Koteswara Rao Valasani et al. ACS Medicinal Chemistry Letters
- Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer’s disease
- (2016) Po-Ting Chen et al. Scientific Reports
- Curcumin Attenuates Beta-Amyloid-Induced Neuroinflammation via Activation of Peroxisome Proliferator-Activated Receptor-Gamma Function in a Rat Model of Alzheimer's Disease
- (2016) Zun-Jing Liu et al. Frontiers in Pharmacology
- How does curcumin work with poor bioavailability? Clues from experimental and theoretical studies
- (2016) Liang Shen et al. Scientific Reports
- Enhancement of Oral Bioavailability of Curcumin by a Novel Solid Dispersion System
- (2015) Liandong Hu et al. AAPS PHARMSCITECH
- Curcumin Binding to Beta Amyloid: A Computational Study
- (2015) Praveen P. N. Rao et al. Chemical Biology & Drug Design
- Kainic Acid-Induced Excitotoxicity Experimental Model: Protective Merits of Natural Products and Plant Extracts
- (2015) Nur Shafika Mohd Sairazi et al. Evidence-based Complementary and Alternative Medicine
- The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update
- (2015) Shatadal Ghosh et al. FOOD AND CHEMICAL TOXICOLOGY
- Optimized curcumin formulations for the treatment of Alzheimer's disease: A patent evaluation
- (2015) Abolfazl Shakeri et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Curcumin inhibits apoptosis by regulating intracellular calcium release, reactive oxygen species and mitochondrial depolarization levels in SH-SY5Y neuronal cells
- (2015) Abdülhadi Cihangir Uğuz et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Synthesis of novel steroidal curcumin derivatives as anti-Alzheimer’s disease candidates: Evidences-based on in vivo study
- (2015) Gamal A. Elmegeed et al. STEROIDS
- Flavonoid-Based Therapies in the Early Management of Neurodegenerative Diseases
- (2015) Isha Solanki et al. Advances in Nutrition
- Dietary Patterns, Cognitive Decline, and Dementia: A Systematic Review
- (2015) Ondine van de Rest et al. Advances in Nutrition
- Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway
- (2015) Lu Zhang et al. PLoS One
- Curcumin Inhibits the AKT/NF-κB Signaling via CpG Demethylation of the Promoter and Restoration of NEP in the N2a Cell Line
- (2014) Yushuang Deng et al. AAPS Journal
- Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-β25–35 in rat cortical neurons
- (2014) Qinru Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Synthesis and evaluation of a 18F-curcumin derivate for β-amyloid plaque imaging
- (2014) Johanna Rokka et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis and evaluation of rivastigmine and curcumin hybrids as site-activated multitarget-directed ligands for Alzheimer’s disease therapy
- (2014) Yujie Li et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models
- (2014) Xue Wang et al. BMC Complementary and Alternative Medicine
- Identification of Human ABAD Inhibitors for Rescuing Aβ-Mediated Mitochondrial Dysfunction
- (2014) Koteswara Valaasani et al. Current Alzheimer Research
- Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice
- (2014) Chen Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Adenosine triphosphate concentrations are higher in the brain of APOE3- compared to APOE4-targeted replacement mice and can be modulated by curcumin
- (2014) Dawn Chin et al. Genes and Nutrition
- Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors
- (2014) Koteswara Rao Valasani et al. Journal of Chemical Information and Modeling
- Curcumin derivatives as metal-chelating agents with potential multifunctional activity for pharmaceutical applications
- (2014) Erika Ferrari et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Curcumin as a wound healing agent
- (2014) Dania Akbik et al. LIFE SCIENCES
- Telomerase: A Target for Therapeutic Effects of Curcumin and a Curcumin Derivative in Aβ1-42 Insult In Vitro
- (2014) Zijian Xiao et al. PLoS One
- Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies
- (2014) Natascia Brondino et al. TheScientificWorldJOURNAL
- Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice
- (2014) Yue-Qin Zeng et al. Frontiers in Neurology
- Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway
- (2013) Shashi Kant Tiwari et al. ACS Nano
- Curcumin Induces ABCA1 Expression and Apolipoprotein A-I-Mediated Cholesterol Transmembrane in the Chronic Cerebral Hypoperfusion Aging Rats
- (2013) Mingyuan Tian et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Synthesis and evaluation of curcumin derivatives toward an inhibitor of beta-site amyloid precursor protein cleaving enzyme 1
- (2013) Hiroyuki Konno et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design, synthesis and anti-Alzheimer properties of dimethylaminomethyl-substituted curcumin derivatives
- (2013) Lei Fang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century
- (2013) Wing-Hin Lee et al. Current Neuropharmacology
- Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 mice
- (2013) Pengwen Wang et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Curcumin attenuates amyloid-β-induced tau hyperphosphorylation in human neuroblastoma SH-SY5Y cells involving PTEN/Akt/GSK-3β signaling pathway
- (2013) Han-Chang Huang et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Curcumin protects organotypic hippocampal slice cultures from Aβ1–42-induced synaptic toxicity
- (2013) Juliana Bender Hoppe et al. TOXICOLOGY IN VITRO
- Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice
- (2012) Kwok Kin Cheng et al. AAPS Journal
- Activation of α-secretase by curcumin-aminoacid conjugates
- (2012) Ramesh B. Narasingapa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Curcumin Suppresses Soluble Tau Dimers and Corrects Molecular Chaperone, Synaptic, and Behavioral Deficits in Aged Human Tau Transgenic Mice
- (2012) Qiu-Lan Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease
- (2012) Miriam A Hickey et al. Molecular Neurodegeneration
- Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics
- (2011) Peizhong Mao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Curcumins Promote Monocytic Gene Expression Related to ß-Amyloid and Superoxide Dismutase Clearance
- (2011) J.R. Cashman et al. Neurodegenerative Diseases
- Evidence of Oxidative Stress in Alzheimer's Disease Brain and Antioxidant Therapy
- (2010) Domenico Praticò Annals of the New York Academy of Sciences
- Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation
- (2010) A. Baghdasaryan et al. GUT
- Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model
- (2010) Dong-Oh Moon et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Curcumin Decreases Amyloid-β Peptide Levels by Attenuating the Maturation of Amyloid-β Precursor Protein
- (2010) Can Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Treatment of Alzheimer’s Disease with a Cholinesterase Inhibitor Combined with Antioxidants
- (2010) Umberto Cornelli Neurodegenerative Diseases
- Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease
- (2010) T. Ahmed et al. NEUROSCIENCE
- Curcumin improves bone microarchitecture and enhances mineral density in APP/PS1 transgenic mice
- (2010) Mao-Wei Yang et al. PHYTOMEDICINE
- Characteristics and Performance of a Modified Version of the ADCS-CGIC CIBIC+ for Mild Cognitive Impairment Clinical Trials
- (2009) Lon S. Schneider et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Donepezil delays progression to AD in MCI subjects with depressive symptoms
- (2009) P. H. Lu et al. NEUROLOGY
- Curcumin inhibits aggregation of α-synuclein
- (2008) Neeraj Pandey et al. ACTA NEUROPATHOLOGICA
- Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease
- (2008) Touqeer Ahmed et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Curcumin-Derived Pyrazoles and Isoxazoles: Swiss Army Knives or Blunt Tools for Alzheimer's Disease?
- (2007) Rajeshwar Narlawar et al. ChemMedChem
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now