Assessment of the Genetic Architecture of Alzheimer’s Disease Risk in Rate of Memory Decline

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms

(2018) Carlos Cruchaga et al.   Alzheimers & Dementia

Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease

(2017) Valentina Escott-Price et al.   NEUROBIOLOGY OF AGING

TREM2 Function in Alzheimer’s Disease and Neurodegeneration

(2016) Jason D. Ulrich et al.   ACS Chemical Neuroscience

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

(2016) Laura Piccio et al.   ACTA NEUROPATHOLOGICA

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

(2016) Celeste Sassi et al.   NEUROBIOLOGY OF AGING

Reflections on the Field of Human Genetics: A Call for Increased Disease Genetics Theory

(2016) Steven J. Schrodi   Frontiers in Genetics

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

(2016) Yuetiva Deming et al.   Scientific Reports

Convergent genetic and expression data implicate immunity in Alzheimer's disease

(2015) Lesley Jones et al.   Alzheimers & Dementia

TREM2 is associated with increased risk for Alzheimer’s disease in African Americans

(2015) Sheng Chih Jin et al.   Molecular Neurodegeneration

The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease

(2015) Eva Louwersheimer et al.   NEUROBIOLOGY OF AGING

Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans

(2015) Jorge L. Del-Aguila et al.   Alzheimers Research & Therapy

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Coding variants in TREM2 increase risk for Alzheimer's disease

(2014) Sheng Chih Jin et al.   HUMAN MOLECULAR GENETICS

Frontobasal gray matter loss is associated with the TREM2 p.R47H variant

(2014) Elkin O. Luis et al.   NEUROBIOLOGY OF AGING

TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis

(2014) Janet Cady et al.   JAMA Neurology

TREM2 and the neuroimmunology of Alzheimer's disease

(2013) Suzanne E. Hickman et al.   BIOCHEMICAL PHARMACOLOGY

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

TREM2 is associated with the risk of Alzheimer's disease in Spanish population

(2013) Bruno A. Benitez et al.   NEUROBIOLOGY OF AGING

GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

(2013) Carlos Cruchaga et al.   NEURON

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

(2010) Andrew J. Saykin et al.   Alzheimers & Dementia

Genetics of Alzheimer disease in the pre- and post-GWAS era

(2010) Nilüfer Ertekin-Taner   Alzheimers Research & Therapy

SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease

(2010) Carlos Cruchaga et al.   PLoS Genetics

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

Stability of the Clinical Dementia Rating, 1979-2007

(2009) Monique M. Williams et al.   ARCHIVES OF NEUROLOGY

Relationships between biomarkers in aging and dementia

(2009) W. J. Jagust et al.   NEUROLOGY

Alzheimer's Disease Neuroimaging Initiative (ADNI): Clinical characterization

(2009) R. C. Petersen et al.   NEUROLOGY

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics