期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 66, 期 17, 页码 4571-4579出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.8b00868
关键词
human colostrum; mature milk; triacylglycerols; fatty acids; UPLC-ESI-MS
资金
- National Natural Science Foundation of China [31371808]
- Special Research Grant for Nonprofit Public Service [201303085]
- Beijing Innovation Team of Technology System in Dairy Industry
Human colostrum is important for immune system development and plays a protective role for infants. However, the comprehensive exploration of lipids, which account for 3-5% of milk, and their biological functions in human colostrum was limited. In present study, the triacylglycerol (TAG) and fatty acid (FA) compositions of human colostrum and mature milk were analyzed and compared. Variations were observed in both the TAG and FA compositions. The concentrations of 18:1/18:1/16:0 TAG, high-molecular-weight and unsaturated TAGs were significantly higher in colostrum, whereas mature milk contained more low/medium-molecular-weight TAGs and medium-chain FAs. Furthermore, there were also specific TAGs in both colostrum and mature milk. Our data highlighted targets for further investigation to elucidate the biological function of lipids in colostrum milk. In addition, the comprehensive analysis of TAGs in Chinese colostrum might help in designing infant formula for Chinese babies, especially the preterm ones.
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