Effect of roflumilast on chronic obstructive pulmonary disease: a systematic review and meta-analysis

Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE2SPOND). A Randomized Clinical Trial

(2016) Fernando J. Martinez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Efficacy and Safety of Roflumilast in Korean Patients with COPD

(2016) Jae Seung Lee et al.   YONSEI MEDICAL JOURNAL

A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease

(2015) J. Michael Wells et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial

(2015) Fernando J Martinez et al.   LANCET

Roflumilast for asthma: Efficacy findings in mechanism of action studies

(2015) P. Bardin et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Roflumilast for asthma: Efficacy findings in placebo-controlled studies

(2015) E.O. Meltzer et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Implementing lessons learned from previous bronchial biopsy trials in a new randomized controlled COPD biopsy trial with roflumilast

(2014) Neil C Barnes et al.   BMC Pulmonary Medicine

Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials

(2014) Stephen Rennard et al.   International Journal of Chronic Obstructive Pulmonary Disease

Roflumilast for the Treatment of COPD in an Asian Population

(2013) Jinping Zheng et al.   CHEST

Pooled subpopulation analyses of the effects of roflumilast on exacerbations and lung function in COPD

(2013) Nicola A. Hanania et al.   RESPIRATORY MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PDE4: A Novel Target in the Treatment of Chronic Obstructive Pulmonary Disease

(2011) J M Michalski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Physiological effects of roflumilast at rest and during exercise in COPD

(2011) Denis E. O’Donnell et al.   EUROPEAN RESPIRATORY JOURNAL

Roflumilast with long-acting  2-agonists for COPD: influence of exacerbation history

(2011) E. D. Bateman et al.   EUROPEAN RESPIRATORY JOURNAL

Roflumilast in Asian patients with COPD: A randomized placebo-controlled trial

(2011) SANG-DO LEE et al.   RESPIROLOGY

Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

(2009) Leonardo M Fabbri et al.   LANCET

Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials

(2009) Peter MA Calverley et al.   LANCET