期刊
GENETICS AND MOLECULAR BIOLOGY
卷 38, 期 3, 页码 278-283出版社
SOC BRASIL GENETICA
DOI: 10.1590/S1415-475738320150009
关键词
Tribolium; mlpt; pri; tarsal-less; Drosophila
资金
- Fundacao de Amparo de Pesquisa do Estado do Rio de Janeiro (FAPERJ)
- Conselho Nacional de Pesquisa (CNPq)
- Fundacao Educacional de Macae (FUNEMAC)
- PIBIC/CNPq scholarship
- FAPERJ scholarship
Genes that contain small open reading frames (smORFs) constitute a new group of eukaryotic genes and are expected to represent 5% of the Drosophila melanogaster transcribed genes. In this review we provide a historical perspective of their recent discovery, describe their general mechanism and discuss the importance of smORFs for future genomic and transcriptomic studies. Finally, we discuss the biological role of the most studied smORF so far, the Mlpt/Pri/Tal gene in arthropods. The pleiotropic action of Mlpt/Pri/Tal in D. melanogaster suggests a complex evolutionary scenario that can be used to understand the origins, evolution and integration of smORFs into complex gene regulatory networks.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据