Article
Biophysics
Prabhat Tiwari, Hamsawardhini Rengarajan, Timothy E. Saunders
Summary: The study found that the heart of Drosophila scales precisely with embryo length, while the hindgut shows scaling with embryo size under large-scale changes in artificially smaller embryos, but not within wild-type size variation. The VNC displays weak scaling behavior, suggesting it may have an intrinsic minimal length largely independent of embryo length.
BIOPHYSICAL JOURNAL
(2021)
Article
Neurosciences
Artyom Kopp, Olga Barmina
Summary: Drosophila males use leg gustatory bristles to distinguish between male and female cuticular pheromones, which plays a crucial role in courtship behavior. Different Drosophila species have varying numbers and locations of sex-specific gustatory bristles, influencing sexual dimorphism and the evolution of mating behavior.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Fisheries
Siti Umey Syahirah Mat Nawang, Fui Fui Ching, Shigeharu Senoo
Summary: The study describes the development of morphology, sensory organs, and behavioral changes in Amur catfish larvae from 0 h after hatching to 20 days after hatching. The larvae exhibit different swimming behaviors and developmental changes in their eyes, taste buds, and neuromasts. The findings suggest that the development of morphology, sensory organs, and behavior in Amur catfish larvae are interconnected and progress as the larvae age.
AQUACULTURE REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Zhixiong Chen, Yajing Li, Peigang Li, Xiaojie Huang, Mingxin Chen, Jinwen Wu, Lang Wang, Xiangdong Liu, Yajuan Li
Summary: This study identified 671 miRNAs, including 67 known and 44 novel differentially expressed miRNAs in the early stage of rice inflorescence development. Unique expression patterns of miRNAs were detected, with osa-miR5506 playing a crucial role in regulating floral organ number, spikelet determinacy, and female gametophyte development in rice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Dong Li, Ying Ge, Ze Zhao, Rui Zhu, Xiang Wang, Xiaolin Bi
Summary: The study analyzed the expression profiles of miRNAs and piRNAs in Drosophila during development and DNA damage response, revealing dynamic expression patterns and the key roles of E2f1 and p53 in regulating small ncRNAs. E2f1 may play a major role in modulating miRNAs during development and after X-ray irradiation, showcasing new insights into small ncRNA biology.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Daniel C. C. Quesnelle, William G. G. Bendena, Ian D. D. Chin-Sang
Summary: MicroRNAs play a critical role in regulating post-transcriptional gene expression in various taxa. Their presence has been identified in almost all aspects of development since their discovery in the nematode C. elegans. Invertebrate model organisms, especially C. elegans and Drosophila melanogaster, are ideal for studying miRNA function, and this review compiles the functions of miRNAs in the development of these invertebrate species. The regulation of gene expression by miRNAs shapes both embryonic and larval development, and several trends can be observed in their regulatory nature.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Lovisa Oerkenby, Signe Skog, Helen Ekman, Alessandro Gozzo, Unn Kugelberg, Rashmi Ramesh, Srivathsa Magadi, Gianluca Zambanini, Anna Nordin, Claudio Cantu, Daniel Naett, Anita Oest
Summary: Early-life stress can lead to long-term effects on adult health and disease risk, and this study reveals that these effects can be initiated in Drosophila embryos before the main wave of zygotic transcription. The researchers found that a short heat shock in early embryos resulted in changes in maternal miRNA and the expression of certain genes. They propose that maternal miRNAs, retained in response to an early embryonic heat shock, play a role in shaping the establishment of heterochromatin during early development.
MOLECULAR SYSTEMS BIOLOGY
(2023)
Article
Medicine, Research & Experimental
Zia Ul Islam, Umul Baneen, Taqdees Khaliq, Syed Muhammad Nurulain, Zahid Muneer, Sabir Hussain
Summary: This study investigated the association of miRNA-146a and miRNA-499 polymorphisms with rheumatoid arthritis (RA) in Pakistani patients. The results showed significant associations between miRNA-146a and miRNA-499 genotypes and RA, suggesting a genetic link. These findings contribute to a better understanding of the pathogenesis and genetic factors of RA.
CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Juan A. Sanchez, Maria C. Ingaramo, Maria P. Gerve, Maria G. Thomas, Graciela L. Boccaccio, Andres Dekanty
Summary: The adipose tissue plays a crucial role in metabolism, stress resistance, and longevity. The depletion of Dicer1 in the fat body leads to changes in lipid metabolism, enhanced resistance to stress, and increased lifespan. The JNK-FOXO axis controls nutrient responses in the fat body by suppressing Dicer1 expression, providing a novel understanding of physiological responses at the organismal level.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Marialuisa Aragona, Caterina Porcino, Maria Cristina Guerrera, Giuseppe Montalbano, Rosaria Laura, Marzio Cometa, Maria Levanti, Francesco Abbate, Teresa Cobo, Gabriel Capitelli, Jose A. Vega, Antonino Germana
Summary: This review provides an update on the distribution and functions of the BDNF-TrkB system in the sensory organs of zebrafish, highlighting its significance in fish.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Neurosciences
Anthony M. Rossi, Shadi Jafari, Claude Desplan
Summary: During Drosophila neurogenesis, neural stem cells produce a variety of neurons through spatial and temporal patterning mechanisms. Simple patterning systems like Notch can be reiteratively used to generate different neuronal types, while different modes of temporal patterning may be linked. Integration of specification programs leads to the terminal features of different neuronal types.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 44, 2021
(2021)
Article
Entomology
Ya-Nan Hou, Ying-Ying Zhang, Ya-Ru Wang, Zhi-Mao Wu, Yun-Xia Luan, Qing Wei
Summary: Cilia are hair-like organelles involved in sensory function or motility, playing critical roles in physiological processes. In Drosophila, the formation of cilia remains poorly understood. We investigated the role of IFT52, a core component of IFT-B, and found it is essential for sensory cilia formation and function in insects.
Review
Biotechnology & Applied Microbiology
Yan Huang, Zhigang He, Anne Manyande, Maohui Feng, Hongbing Xiang
Summary: This review focuses on the knowledge of nerve regeneration after heart, liver, and kidney transplantation and applies various imaging techniques to assess the prognosis of organ transplantation. The aim is to provide theories and insights into nerve regeneration in organ transplantation for clinicians and nuclear medicine researchers, and to advance imaging techniques and radiotracers as a major step forward in clinical research.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biology
Giovanni Frighetto, Mark A. Frye
Summary: Drosophila uses smooth optomotor movements to stabilize gaze and impulsive saccades to pursue vertical bars, with T4 and T5 cells providing inputs for gaze stabilization and T3 cells driving bar tracking body saccades. Silencing T3 reduces tracking saccades, while optogenetic manipulation affects saccade rate. Smooth optomotor responses remain unaffected. Parallel neural pathways coordinate gaze stabilization and saccadic bar tracking behavior in flight.
Article
Biochemistry & Molecular Biology
Alexander K. Murashov, Elena S. Pak, Jordan Mar, Kevin O'Brien, Kelsey Fisher-Wellman, Krishna M. Bhat
Summary: Multiple lines of evidence suggest that ancestral diet plays a crucial role in determining the metabolic traits of offspring. However, its impact on offspring's food choices and feeding behavior remains unclear. Using a Drosophila model system, this study demonstrates that a paternal Western diet (WD) increases food consumption in offspring up to the fourth generation and induces alterations in brain proteome. Further analysis reveals that the upregulated proteins are associated with translation and translation factors, while the downregulated proteins are related to small molecule metabolic processes, TCA cycles, and electron transport chain (ETC). The identification of miR-10 as a potential factor in programming feeding behavior suggests that ancestral nutrition may influence offspring's feeding behavior through alterations in miRNAs.
Article
Otorhinolaryngology
Alexander J. Straughan, Pamela A. Mudd, Allison L. Silva, Susan S. Callicott, Gina Krakovsky, Nancy M. Bauman
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2019)
Review
Otorhinolaryngology
Alexander J. Straughan, Collin F. Mulcahy, Anthony D. Sandler, Nancy M. Bauman, David Steinhorn, Lyuba Gitman
Summary: A novel surgical approach for managing tracheal agenesis is described in this report, which avoids the creation of a spit fistula and preserves the native esophagus. The literature review included the survivorship duration and operative management of 174 reported cases of tracheal agenesis.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2021)
Letter
Otorhinolaryngology
Alexander J. Straughan, Philip E. Zapanta, Joseph F. Goodman
Summary: This article discusses Follow-Up Phone Interviews and Attendance Motivation From A Free Head and Neck Cancer Screening, providing valuable insights into the motivational factors for participating in screenings.
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Article
Otorhinolaryngology
Alexander J. Straughan, Luke J. Pasick, Vrinda Gupta, Daniel A. Benito, Joseph F. Goodman, Philip E. Zapanta
Summary: This study examined head and neck injuries associated with fireworks use in the United States from 2010 to 2019. Results showed that young, white, and male individuals were more likely to be injured, with burns being the most common type of injury. Efforts to prevent these injuries need to be strengthened as rates have not significantly improved over the past decade.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Alexandra H. B. Helbing, Alexander J. Straughan, Luke J. Pasick, Daniel A. Benito, Philip E. Zapanta
Summary: Ear foreign bodies are a significant concern in emergency department visits nationwide, with females more likely to have jewelry and first aid equipment lodged in their ears, while males tend to have paper products, pens/pencils, and desk supplies inserted.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2022)
Article
Medicine, General & Internal
Alexander J. Straughan, Christopher Badger, Ramin Javan, Andrew Fuson, Arjun S. Joshi
