Variation in the CTLA4 3′UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes

Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

(2014) Laura Esposito et al.   JOURNAL OF IMMUNOLOGY

Post-transcriptional control of candidate risk genes for type 1 diabetes by rare genetic variants

(2012) V M de Jong et al.   GENES AND IMMUNITY

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

(2011) Tihamer Orban et al.   LANCET

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

CTLA4 −1661A/G and 3′UTR long repeat polymorphisms are associated with ulcerative colitis and influence CTLA4 mRNA and protein expression

(2010) Z Chen et al.   GENES AND IMMUNITY

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Genetic Evidence That the Differential Expression of the Ligand-Independent Isoform of CTLA-4 Is the Molecular Basis of the Idd5.1 Type 1 Diabetes Region in Nonobese Diabetic Mice

(2009) M. Araki et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

CTLA-4 suppresses the pathogenicity of self antigen–specific T cells by cell-intrinsic and cell-extrinsic mechanisms

(2009) Wataru Ise et al.   NATURE IMMUNOLOGY

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Identification of CTLA-4 isoforms produced by alternative splicing and their association with myasthenia gravis

(2008) Ming Gu et al.   CLINICAL IMMUNOLOGY

Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data

(2008) Frank Dudbridge   HUMAN HEREDITY

Post-transcriptional control of cytokine production

(2008) Paul Anderson   NATURE IMMUNOLOGY

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE