Article
Environmental Sciences
Adjani A. Peralta, Joel Schwartz, Diane R. Gold, Brent Coull, Petros Koutrakis
Summary: Exposure to metals in PM2.5 is associated with acute changes in ventricular repolarization, with higher lead concentrations significantly increasing QT intervals. Copper showed a negative association with QT intervals, possibly due to its essential function in the human body.
ENVIRONMENTAL RESEARCH
(2021)
Article
Medicine, Research & Experimental
Ishant Khurana, Harikrishnan Kaipananickal, Scott Maxwell, Sorine Birkelund, Anna Syreeni, Carol Forsblom, Jun Okabe, Mark Ziemann, Antony Kaspi, Haloom Rafehi, Anne Jorgensen, Keith Al-Hasani, Merlin C. Thomas, Guozhi Jiang, Andrea O. Y. Luk, Heung Man Lee, Yu Huang, Yotsapon Thewjitcharoen, Soontaree Nakasatien, Thep Himathongkam, Christopher Fogarty, Rachel Njeim, Assaad Eid, Tine Willum Hansen, Nete Tofte, Evy C. Ottesen, Ronald C. W. Ma, Juliana C. N. Chan, Mark E. Cooper, Peter Rossing, Per-Henrik Groop, Assam El-Osta
Summary: Diabetic nephropathy (DN) is a polygenic disorder with poorly defined genome-wide methylation patterns. Methylation sequencing using leukocytes from a Finnish diabetes study identified differentially methylated genes associated with DN, which were further validated in independent T1D registries from Denmark, Hong Kong, and Thailand. Reduced DNA methylation at certain sites was connected with DN pathways related to insulin signaling, lipid metabolism, and fibrosis. Experimental observations in human renal cells, macrophages, and vascular endothelial cells supported the findings.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Environmental Sciences
Yatai Men, Jianpeng Li, Xinlei Liu, Yaojie Li, Ke Jiang, Zhihan Luo, Rui Xiong, Hefa Cheng, Shu Tao, Guofeng Shen
Summary: Indoor air quality is crucial to human health, especially in rural areas where household air pollution from solid fuel use is often overlooked. A study found that indoor PM2.5 is influenced by internal sources and outdoor PM2.5, with different relationships between indoor and outdoor levels in heating and non-heating seasons.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Ivan Y. Hernandez Paniagua, Omar Amador Munoz, Irma Rosas Perez, Oscar Arrieta Garcia, Raymundo I. Gonzalez Buendia, Gema L. Andraca Ayala, Aron Jazcilevich
Summary: This study evaluates the impacts of technological updates on BRT systems on commuters' exposure to PM2.5 and PAHs. The results show that PM2.5 concentrations significantly decreased by 35% from Euro IV to Euro V buses, and by 80% from Euro IV to Euro VI buses. The PM2.5 concentrations inside Euro VI buses were significantly lower than in Euro IV and Euro V buses and underground trains. This research demonstrates that advanced diesel technologies and cabin design effectively reduce commuters' exposure to PM2.5 and toxic PAH compounds.
ENVIRONMENTAL POLLUTION
(2023)
Article
Endocrinology & Metabolism
Angier Allen, Zohora Iqbal, Abigail Green-Saxena, Myrna Hurtado, Jana Hoffman, Qingqing Mao, Ritankar Das
Summary: This study aims to develop a machine learning algorithm that predicts the stages of diabetic kidney disease within 5 years after diagnosis of type 2 diabetes mellitus.
BMJ OPEN DIABETES RESEARCH & CARE
(2022)
Article
Environmental Sciences
Meredith Pedde, Itai Kloog, Adam Szpiro, Michael Dorman, Sara D. Adar, Timothy V. Larson
Summary: The limited ground-level measurement data makes it challenging to assess the health risks of PM10-2.5, but utilizing Aerosol Optical Depth (AOD) data from satellites can offer opportunities for broader estimation. This study used NASA's Terra satellite measurements to estimate long-term PM10-2.5 concentrations in six urban areas in the US. The predictions based on AOD data were well correlated with measured levels, indicating the potential for combining AOD data with land use regression to estimate localized PM10-2.5 concentrations.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Ophthalmology
Lanhua Wang, Ling Jin, Wei Wang, Xia Gong, Yuting Li, Wangting Li, Xiaoling Liang, Wenyong Huang, Yizhi Liu
Summary: There is a strong association between renal function and vision-threatening diabetic retinopathy (VTDR) and diabetic macular oedema (DMO) in diabetic patients. The association between glomerular filtration rate (GFR) and VTDR is significant, while the association with any DR depends on the presence of microalbuminuria. High microalbuminuria and chronic kidney disease (CKD) are significantly associated with DMO.
Article
Economics
Evangelina Dardati, Ramiro de Elejalde, Eugenio Giolito
Summary: This paper investigates the short-term effect of PM 2.5 exposure on respiratory emergency room visits in Chile. The study finds that a 1μg/m3 increase in PM 2.5 exposure leads to a 0.36% increase in ER visits for respiratory illness. The effect is significant for all age groups, and avoidance behavior becomes increasingly significant as environmental alerts get stricter.
Article
Multidisciplinary Sciences
Daniele Pala, Vittorio Casella, Cristiana Larizza, Alberto Malovini, Riccardo Bellazzi
Summary: In the Po Valley in northern Italy, air pollution is a serious concern due to factors such as high population density and industrial activity. During the lockdown, there was a reduction in car traffic and industrial activity, but a drastic decrease in pollution levels was not observed. Factors such as weather conditions and other external factors play a role in determining the severity of pollution.
Article
Engineering, Environmental
Peng Yin, Huihuan Luo, Ya Gao, Wei Liu, Su Shi, Xinyue Li, Xia Meng, Haidong Kan, Maigeng Zhou, Guanglin Li, Renjie Chen
Summary: This study conducted an individual-level case-crossover study among over 0.9 million diabetes deaths in China, and found that there were associations between air pollution and diabetes mortality, with stronger associations observed in type 2 diabetes. Air pollutants were also related to diabetic ketoacidosis and diabetic nephropathy.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Multidisciplinary Sciences
Wasana Chankham, Sa-Aat Niwitpong, Suparat Niwitpong
Summary: This study proposed confidence intervals for the coefficient of variation (CV) of an inverse Gaussian (IG) distribution to calculate PM2.5 concentrations. The performance of these intervals was evaluated through simulation experiments and it was found that the fiducial confidence interval (FCI) performed the best, especially for small sample sizes.
Article
Environmental Sciences
Meng Xiu, Rohan Jayaratne, Phong Thai, Bryce Christensen, Isak Zing, Xiaoting Liu, Lidia Morawska
Summary: This study proposes a simplified method using source signatures to obtain information about local pollution sources. The research found significant differences in CO/PM2.5 ratios among different pollutant sources, suggesting that this ratio can be an effective method for identifying pollution sources.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Rasoul Ameri, Chung-Chian Hsu, Shahab S. Band, Mazdak Zamani, Chi-Min Shu, Sajad Khorsandroo
Summary: With urbanization and increasing consumption, prioritizing sustainable development is crucial. Air pollution, caused by combustion gases containing PM 2.5, hampers sustainable development. This study proposes a novel approach combining SVM, LSTM, and CEEMDAN for accurate PM 2.5 forecasting. The proposed model outperforms other methods in terms of accuracy and demonstrates superior performance.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Urology & Nephrology
Kohjiro Ueki, Takayoshi Sasako, Yukiko Okazaki, Kana Miyake, Masaomi Nangaku, Yasuo Ohashi, Mitsuhiko Noda, Takashi Kadowaki
Summary: The study evaluated the effects of intensified multifactorial intervention on diabetic kidney disease in patients with type 2 diabetes. Results showed a significant reduction in kidney events and progression compared to standard care, indicating the effectiveness of intensified intervention in preventing diabetic kidney disease.
KIDNEY INTERNATIONAL
(2021)
Review
Medical Laboratory Technology
Zhaohui Cao, Di Huang, Cifei Tang, Yang Lu, Shuangxiang Huang, Cuiying Peng, Xiaobo Hu
Summary: This mini-review discusses the molecular mechanisms of inflammasome activation and pyroptosis, highlighting their crucial role in diabetic nephropathy (DN). Natural plant compounds show therapeutic potential in regulating inflammasomes and pyroptosis.
CLINICA CHIMICA ACTA
(2022)
Article
Public, Environmental & Occupational Health
Wei-Shan Chin, Shih-Cheng Liao, Shin-Chun Pan, Yue-Liang Leon Guo
Summary: This study investigated and compared the effects of occupational injury, non-occupational injury, and no injury on the development of psychiatric diseases. The results showed that both occupational injury and non-occupational injury were associated with increased incidence of psychiatric disorders, highlighting the importance of long-term psychological care among injured workers in workers' compensation mechanisms.
JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Nursing
Yi-Chuan Chen, Hsueh-Ching Wu, Feng-Tze Kuo, David Koh, Yue-Liang Leon Guo, Judith Shu-Chu Shiao
Summary: The study aimed to identify factors contributing to hospital healthcare workers' intention to leave during the COVID-19 pandemic. The findings revealed that perceived risk, affected social relationships, increased workload, and job stress were positively associated with the intention to leave, while supportive administration and management acted as protective factors. Developing workplace strategies to address these factors is crucial for improving the wellbeing of healthcare workers and promoting stability in the workforce.
JOURNAL OF NURSING SCHOLARSHIP
(2022)
Article
Audiology & Speech-Language Pathology
I-Fan Lin, Perng-Jy Tsai, Jiunn-Liang Wu, Wei-Shan Chin, Cheng-Yu Lin, Yue Leon Guo
Summary: This study aimed to differentiate noise-induced hearing loss (NIHL) from age-related hearing loss by examining the characteristics of distortion product otoacoustic emissions (DPOAEs). The results showed that DPOAEs and DPOAE signal-to-noise ratios (SNRs) were correlated with age at all frequencies, and were correlated with both age and noise exposure at 2 kHz, 3 kHz, 4 kHz, and 6 kHz. The difference between DPOAE SNRs at 1 kHz and 3 kHz showed significant correlation with noise exposure but not with age.
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Rou-Shiuan Huang, Yi-Chuan Chen, Shang-Yin Tsai, Yan-Siang Eason Huang, Yue-Liang Leon Guo
Summary: This study examined the sleep problems among firefighters in Taiwan and identified the factors associated with poor sleep quality. The results showed that more than three-quarters of firefighters had poor sleep quality and it was influenced by demographic characteristics such as age, working tenure, having children, and chronotype, as well as work-related characteristics including shift schedule and incomplete off-duty hours. The study suggests that firefighters should have complete off-duty days to avoid poor sleep quality and recommends implementing appropriate shift schedules to ensure adequate rest time.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2023)
Article
Clinical Neurology
Ping Shih, Tung-liang Chiang, Chih-Da Wu, Bih-Ching Shu, For-Wey Lung, Yue Leon Guo
Summary: Exposure to ambient PM2.5 during pregnancy is significantly associated with delay in gross motor, fine motor, and personal-social development in infants.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Environmental Sciences
Yi-Chuan Chen, Wei-Shan Chin, Shih-Chun Pan, Chih-Da Wu, Yue-Liang Leon Guo
Summary: This study examined the association between long-term exposure to air pollutants and the occurrence of MetS and its components. The results showed that an increase in annual PM2.5 concentration was associated with an increased risk of abdominal obesity, hypertriglyceridemia, low HDL-C, hypertension, and elevated fasting blood glucose. Additionally, PM2.5 and NO2 may increase the risk of developing MetS among people who already have some components of Met.S.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Respiratory System
Yue Leon Guo, Maria R. Ampon, Leanne M. Poulos, Sharon R. Davis, Brett G. Toelle, Guy B. Marks, Helen K. Reddel
Summary: This study estimated the contribution of obesity to breathlessness in Australian adults using the population attributable fraction (PAF). The results showed that obesity accounted for approximately a quarter of breathlessness symptoms and had a higher proportion in women.
Letter
Respiratory System
Chen He, Renjie Chen, Ho Kim, Masahiro Hashizume, Whanhee Lee, Yasushi Honda, Satbyul Estella Kim, Yue Leon Guo, Alexandra Schneider, Wenzhen Ge, Yixiang Zhu, Lu Zhou, Haidong Kan
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Psychiatry
Ping Shih, Tung-liang Chiang, Ping- Lin, Ming-Yu Lin, Yue Leon Guo
Summary: The study found that higher maternal screen time in early childhood was associated with an increased risk of children developing ADHD, while there was no significant association between children's or fathers' screen time and ADHD. Further research is needed to confirm the specific mechanisms underlying this association.
Article
Environmental Sciences
Mu-Jean Chen, Yue Leon Guo, Pinpin Lin, Hung-Che Chiang, Pau-Chung Chen, Yu-Cheng Chen
Summary: The currently used air quality index (AQI) is criticized for its inability to capture the additive effects of air pollution on health risks and reflect non-threshold concentration-response relationships. In this study, we propose the air quality health index (AQHI) based on daily air pollution-mortality associations and compare its validity in predicting daily mortality and morbidity risks with the existing AQI.
ENVIRONMENTAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Samuel Luthi, Christopher Fairless, Erich M. Fischer, Noah Scovronick, Micheline De Sousa Zanotti Stagliorio Coelho, Yue Leon Guo, Yuming Guo, Yasushi Honda, Veronika Huber, Jan Kysely, Eric Lavigne, Dominic Roye, Niilo Ryti, Susana Silva, Ales Urban, Antonio Gasparrini, David N. Bresch, Ana M. Vicedo-Cabrera
Summary: Current research focuses on the impact of rising temperatures on heat-related mortality, but it is unclear how climate change will exacerbate the effects of extreme summer seasons on human health. This study combines empirical heat-mortality relationships with climate model data to predict future highly impactful summer seasons. The findings emphasize the urgent need for mitigation and adaptation measures to reduce the impact on human lives.
NATURE COMMUNICATIONS
(2023)
Article
Medicine, General & Internal
Cong Liu, Renjie Chen, Francesco Sera, Ana Maria Vicedo-Cabrera, Yuming Guo, Shilu Tong, Eric Lavigne, Patricia Matus Correa, Nicolas Valdes Ortega, Souzana Achilleos, Dominic Roye, Jouni J. K. Jaakkola, Niilo Ryti, Mathilde Pascal, Alexandra Schneider, Susanne Breitner, Alireza Entezari, Fatemeh Mayvaneh, Raanan Raz, Yasushi Honda, Masahiro Hashizume, Chris Fook Sheng Ng, Vania Gaio, Joana Madureira, Iulian-Horia Holobaca, Aurelio Tobias, Carmen Iniguez, Yue Leon Guo, Shih-Chun Pan, Pierre Masselot, Michelle L. Bell, Antonella Zanobetti, Joel Schwartz, Antonio Gasparrini, Haidong Kan
Summary: This study investigated the interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at a global level. The results showed a synergistic effect of PM2.5 and O3 on total, cardiovascular, and respiratory mortality, particularly in high latitude regions and during cold seasons. This highlights the importance of coordinated control strategies for both pollutants.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Biotechnology & Applied Microbiology
Ardha Ardea Prisilla, Yue Leon Guo, Yih-Kuen Jan, Chih-Yang Lin, Fu-Yu Lin, Ben-Yi Liau, Jen-Yung Tsai, Peter Ardhianto, Yori Pusparani, Chi-Wen Lung
Summary: This study aims to detect lumbar disc herniation (LDH) in magnetic resonance imaging (MRI) using deep learning algorithms. The results show that YOLOv5x performs the best in LDH detection, and using a dataset of 550 images with augmentation provides reliable detection in both augmented and non-augmented datasets.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mei-Fang Cheng, Yue Leon Guo, Ruoh-Fang Yen, Yen-Wen Wu, Hsiu-Po Wang
Summary: This study aimed to determine whether inflammation levels detected by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) could predict disease relapse in immunoglobulin G4-related disease (IgG4-RD) patients receiving standard induction steroid therapy. The results showed that whole-body total lesion glycolysis (WTLG) > 600 on FDG-PET was an independent risk factor for disease relapse, and could be used for guiding the treatment and management of IgG-RD patients.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Environmental Sciences
Wei-Shan Chin, Ling-Chu Chien, Ho-Ching Kao, Yung-Ning Chuang, Kai-Wei Liao
Summary: This study aimed to determine the levels of trace elements in green tea, black tea, and Oolong tea consumed as bottled or hand-shaken tea, and estimate the associated health risks. The results showed that hand-shaken green tea had a higher percentage of hazard index (HI) >1 among all age groups. For carcinogenic risks, the exposure risks of As from bottled Oolong tea and hand-shaken black, green, and Oolong teas were higher than 10(-6) in certain age groups. This study provided valuable information about trace elements in bottled and hand-shaken tea and their health risks in Taiwan's general population.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Dewan Muhammad Shoaib, Tanvir Ahmed, Kazy Farhat Tabassum, Mehedi Hasan, Fazle Sharior, Mahbubur Rahman, Makfie Farah, Md Azizur Rahman, Alauddin Ahmed, James B. Tidwell, Mahbub-Ul Alam
Summary: An intervention was implemented in Bangladesh during COVID-19 to reduce occupational health risks for waste and sanitation workers. The intervention involved training and distribution of personal protective equipment (PPE). The study found that the intervention improved workers' knowledge, attitude, and practice regarding PPE usage.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Andreas Kortenkamp, Olwenn Martin, Eleni Iacovidou, Martin Scholze
Summary: The European Food Safety Authority's downward revision of the Health-based Guidance Value for bisphenol A (BPA) has led to disagreements with other regulatory agencies, particularly the German Federal Institute for Risk Assessment. The differing views between EFSA and BfR are driven by their respective selection of endpoints and study evaluation systems, as well as their acceptance or refusal of immunotoxic effects as a basis for establishing a Health-based Guidance Value.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Shizhen He, Bjorn Lundberg, Jenny Hallberg, Susanna Klevebro, Goran Pershagen, Kristina Eneroth, Erik Melen, Matteo Bottai, Olena Gruzieva
Summary: Early life air pollution exposure and abnormal inflammation-related protein profiles may interact synergistically towards lower lung function in infants.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Paulien Cleys, Emilie Hardy, Yu Ait Bamai, Giulia Poma, Adam Cseresznye, Govindan Malarvannan, Paul T. J. Scheepers, Susana Viegas, Simo P. Porras, Tiina Santonen, Lode Godderis, Jelle Verdonck, Katrien Poels, Carla Martins, Maria Joao Silva, Henriqueta Louro, Inese Martinsone, Lasma Akulova, An van Nieuwenhuyse, Martien Graumans, Selma Mahiout, Radu Corneliu Duca, Adrian Covaci
Summary: The aim of this study was to assess the exposure of e-waste workers to phthalates and alternative plasticizers. The results showed that e-waste workers had higher urinary concentrations of phthalates and metabolites compared to non-occupationally exposed controls. However, no significant differences were found between pre-and post-shift concentrations in the e-waste workers.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Karolina Bralewska
Summary: This review study examines the concentrations of various air pollutants in fire stations, identifies the limitations and strengths of existing research, identifies research gaps and challenges, and suggests potential solutions for reducing firefighter exposure to air pollution at fire stations.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)