Article
Nanoscience & Nanotechnology
Changchang Kong, Shijunyin Chen, Wenhao Ge, Yang Zhao, Xiaodong Xu, Shiming Wang, Jianfa Zhang
Summary: In this study, an antibacterial and anti-inflammatory wound dressing based on riclin and silver nanoparticles was developed. The results showed that the dressing had sustained release of silver nanoparticles, effectively suppressed pathogen growth, and had negligible toxicity to human cells. In addition, it promoted faster and smoother wound healing while reducing the expression of inflammatory mediators.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Chemistry, Applied
Xiangyan Chen, Hongjin Li, Xiaoni Qiao, Tianze Jiang, Xue Fu, Yue He, Xia Zhao
Summary: Marine agarose oligosaccharides and silver nanoparticles combined with antimicrobial peptides form a novel composite nanomaterial, which shows significant promoting effects on wound healing with strong antimicrobial activities and good biocompatibility.
CARBOHYDRATE POLYMERS
(2021)
Review
Polymer Science
Fahad M. Aldakheel, Marwa M. El Sayed, Dalia Mohsen, Mohammed H. Fagir, Dalia K. El Dein
Summary: Wound healing is a complex biological process, and nanotechnology, particularly the use of silver nanoparticles (AgNPs), has gained attention for its potential in enhancing this process. AgNPs offer advantages such as easy synthesis and high surface area, which make them efficient for topical drug administration and wound healing. Green synthesis methods utilizing natural sources have been found to be eco-friendly. Characterization techniques such as UV-Vis spectroscopy, FT-IR, SEM, TEM, and XRD are employed to confirm the specific properties of AgNPs. This review highlights the potential of green-synthesized AgNPs loaded in Polyacrylamide hydrogel for advanced wound healing therapies.
Review
Pharmacology & Pharmacy
Sibusiso Alven, Buhle Buyana, Zizo Feketshane, Blessing Atim Aderibigbe
Summary: Nanofibrous scaffolds loaded with silver nanoparticles show promising biological and mechanical outcomes in wound healing, with good antibacterial and bioactive properties.
Article
Polymer Science
Irina Popescu, Marieta Constantin, Gheorghe Solcan, Daniela Luminita Ichim, Delia Mihaela Rata, Loredana Horodincu, Carmen Solcan
Summary: In this study, a composite hydrogel based on chitosan (CS) and polyvinyl alcohol (PVA) embedding silver nanoparticles (AgNPs) with antibacterial properties and ibuprofen (Ib) as an anti-inflammatory agent was developed. The hydrogel displayed good mechanical properties, high swelling degree, sustained drug delivery, and showed strong antibacterial activity. In vivo experiments demonstrated that the hydrogel accelerated wound healing process by activating downstream cascades and supporting the healing process of inflammation and promoting cell migration and proliferation.
Article
Materials Science, Multidisciplinary
Huixing Liang, Maryam Sadat Mirinejad, Azadeh Asefnejad, Hadi Baharifar, Xiang Li, Saeed Saber-Samandari, Davood Toghraie, Amirsalar Khandan
Summary: Wound healing is a complex process that sometimes requires external stimuli. The use of biological agents in wound dressings can modify the healing process and promote better recovery. In this study, a bio-nanocomposite wound dressing containing different weight percentages of AgO-TiO2 nanoparticles was fabricated and characterized for its physical and chemical properties, as well as bioactivity and biodegradability.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Polymer Science
Whijitra Suvandee, Veerawat Teeranachaideekul, Nutjaree Jeenduang, Patcharakamon Nooeaid, Arthit Makarasen, Laemthong Chuenchom, Supanna Techasakul, Decha Dechtrirat
Summary: This study developed a spray-on wound dressing by combining polyvinylpyrrolidone solution, silver nanoparticles, and Phyllanthus emblica extract. The dressing film showed controlled release of fruit extract, high antioxidant activity, and good antibacterial action. Furthermore, the dressing demonstrated biocompatibility with human cells.
Article
Chemistry, Applied
M. R. El-Aassar, Omar M. Ibrahim, Moustafa M. G. Fouda, Hala Fakhry, Jamaan Ajarem, Saleh N. Maodaa, Ahmed A. Allam, Elsayed E. Hafez
Summary: The wound dressing made of chitosan, gelatin, polyvinyl pyrmlidone, and embedded silver nanoparticles showed strong antibacterial activity against pathogenic bacteria and reduced the expression of antibiotic resistance genes. This cost-effective membrane has a promising application in treating severe diabetic and burn wound infections.
CARBOHYDRATE POLYMERS
(2021)
Article
Environmental Studies
Nur Syakirah Rabiha Rosman, Noor Aniza Harun, Izwandy Idris, Wan Iryani Wan Ismail
Summary: This paper critically reviews the global consumption of silver nanoparticles, compares their synthesis methods, and discusses their applications in various fields. Challenges and prospects of biosynthesised silver nanoparticles were also explored.
ENERGY & ENVIRONMENT
(2021)
Article
Biotechnology & Applied Microbiology
Chuanliang Liu, Yuhua Zhu, Xuejie Lun, Huan Sheng, Anquan Yan
Summary: A chitosan electrospun nanofibrous material containing Cur@beta-CD/AgNPs nanoparticles showed dual antibacterial and tissue repair properties. In vivo experiments demonstrated that it promoted wound closure and improved collagen distribution compared to commercial dressings.
Article
Polymer Science
Ogun Bozkaya, Esra Arat, Zehra Gun Gok, Mustafa Yigitoglu, Ibrahim Vargel
Summary: The aim of this study was to develop a therapeutic and antimicrobial nanofiber wound dressing material with suitable physical properties. This was achieved by synthesizing Centella asiatica coated silver nanoparticles and electrospinning them with poly caprolactone and polyethylene oxide to produce hybrid nanofibers. The surface and physico-chemical properties were characterized, and the degradation and antimicrobial properties were investigated. The results demonstrated the potential of this material for wound healing applications.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Materials Science, Biomaterials
Cai He, Xiaofei Liu, Ziyi Zhou, Na Liu, Xuchao Ning, Yuanxin Miao, Yunze Long, Tong Wu, Xiangfeng Leng
Summary: The study successfully designed and fabricated a sandwich wound dressing by incorporating silver nanoparticles into nanofibers to balance antimicrobial activity and biocompatibility, showing competitive antimicrobial properties, lower cell toxicity, and accelerated wound closure for mouse skin injury. Balancing the biocompatibility of electrospun nanofibers and the broad-spectrum antibacterial activity of AgNPs within a sandwich structure, the novel multifunctional wound dressing could be valuable for effective wound healing and related applications.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Jianwei Zheng, Kelin Li, Yue Li, Ge Jiang
Summary: A carboxymethyl chitosan/x-carrageenan (CMCS/x-C) sponge incorporated with green silver nanoparticles (AgNPs) was prepared for wound dressing. The size and morphology of AgNPs and the characteristics of the CMCS/x-C sponge were investigated. The results showed that the CMCS-prepared AgNPs had a particle size of around 10 nm, and the optimal mass ratio of CMCS and x-C in the sponge was 1:1. The CMCS/x-C sponge with AgNPs exhibited antibacterial properties, good biocompatibility, and promoted wound healing in SD rats. Therefore, the CMCS/x-C/AgNPs sponge has potential applications as a wound dressing.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Dayane Dotto, Marcio Scatolini, Silvana Pugini, Luci Vercik, Mariza Melo, Andres Vercik, Eliana Rigo
Summary: The development of dressing material based on gelatine, chitosan and silver nanoparticles shows potential applications in the biomedical field with biocompatibility and antibacterial properties. Different concentrations of AgNPs exhibit varying characteristics, demonstrating high hydration rate and water vapor permeability in the membranes, and show bactericidal effects against Staphylococcus aureus and Pseudomonas aeruginosa.
MATERIALS RESEARCH EXPRESS
(2021)
Article
Pharmacology & Pharmacy
Vajravathi Lakkim, Madhava C. Reddy, VijayaDurga V. V. Lekkala, Veeranjaneya Reddy Lebaka, Mallikarjuna Korivi, Dakshayani Lomada
Summary: Developing an efficient and cost-effective wound-healing substance is urgently needed. Silver nanoparticles synthesized from Azadirachta indica and Catharanthus roseus leaf extracts showed rapid wound healing, increased collagen deposition, and improved antioxidant status in mice. These nanoparticles could be potential natural antioxidants for treating wounds.
Article
Materials Science, Biomaterials
Priscila S. Souza, Raya P. Zaccaron, Franciane T. F. Vasconcellos, Caroline B. De Paula, Eduardo B. B. Cunha, Lucia de Noronha, Paulo E. Feuser, Renata T. Nesi, Marcos M. S. Paula, Paulo C. L. Silveira, Ricardo A. Pinho
Summary: The study demonstrated that ECD-GNPs at a dosage of 0.6 mg/kg improved clinical symptoms, reduced inflammatory infiltrate, and maintained myelin integrity in mice with experimental MS. Furthermore, both GNPs and ECD-GNPs at 0.6 mg/kg showed improvements in the clinical signs of the disease and decreased levels of proinflammatory cytokines.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Materials Science, Multidisciplinary
Jassiel R. Rodriguez, Ysmael Verde-Gomez, Jorge N. Diaz de Leon, Joel Antunez-Garcia, M. Marques da Silva Paula, Trino A. Zepeda, Donald H. Galvan, Gabriel Alonso-Nunez
Summary: This study reports the facile synthesis of Pt-Mn nanoparticles supported on multiwall carbon nanotubes, showing that the electrocatalyst performs best at 40at.% Mn and decreases at 50at.% Mn. Density functional theory computations reveal a correlation between the partial density of states associated with [Mn]3d orbitals and the observed electrocatalytic behavior.
JOURNAL OF MATERIALS RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Nathan Roberto Lohn Pereira, Bruna Lopes, Igor Valezan Fagundes, Fernanda Mendes de Moraes, Fernando Dal Pont Morisso, Gabriel Oscar Cremona Parma, Karine Modolon Zepon, Rachel Faverzani Magnago
Summary: In this study, cellulose from banana pseudostem was acetylated to prepare membranes for potential use as bio-packages. By incorporating Butia seed or pulp extracts, the membranes were evaluated for their physical-chemical, mechanical, thermal, and antibacterial properties. The results showed that the membranes could inhibit the growth of Staphylococcus aureus and Escherichia coli, demonstrating potential for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Parasitology
Guilherme de Oliveira, Harry Luiz Pilz-Junior, Alessandra Bittencourt de Lemos, Felipe Allan da Silva da Costa, Millena Fernandes, Douglas Zelinger Goncalves, Paula Fassicolo Variza, Fernanda Mendes de Moraes, Fernando Dal Pont Morisso, Rachel Faverzani Magnago, Karine Modolon Zepon, Luiz Alberto Kanis, Onilda Santos da Silva, Josiane Somariva Prophiro
Summary: This study evaluated the effectiveness of incorporating piperine into nanostructured systems for controlling Ae. aegypti larvae. The results showed that the nanostructured systems, compared to non-loaded piperine, could slow-release piperine and enhance larvicidal activity. Therefore, loading piperine into nanostructured systems might be an effective approach for improving the control of Ae. aegypti larvae.
Article
Chemistry, Multidisciplinary
Fernanda Mendes de Moraes, Silvana Cristina Trauthman, Francieli Zimmer, Patricia Piovezan Pacheco, Fernando Dal Pont Morisso, Ana Luiza Ziulkoski, Luiz Alberto Kanis, Karine Modolon Zepon
Summary: This study investigated the potential role of using carrageenan/locust bean gum hydrogel to enhance transdermal delivery of hydrophilic actives. The results showed that the kappa C:LBG:AR hydrogel had higher viscosity values, smooth surfaces, and good cytocompatibility in vitro. By changing the structural organization of the lipid bilayer, the kappa C:LBG:AR hydrogel enhanced transdermal delivery and significantly improved skin hydration and reduced melanin index.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2022)
Article
Polymer Science
Rachel Faverzani Magnago, Ana Carolina de Aguiar, Igor Fagundes Valezan, Fernanda Mendes de Moraes, Ana Luiza Ziulkoski, Fernando Dal Pont Morisso, Luiz Alberto Kanis, Karine Modolon Zepon
Summary: In this study, a polycaprolactone-triol-based polyurethane conjugated ibuprofen film (PU-ibu) was synthesized and characterized. The PU-ibu film showed excellent properties and potential as a novel sustained drug delivery system.
EUROPEAN POLYMER JOURNAL
(2022)
Review
Pharmacology & Pharmacy
Morgana Souza Marques, Lorena Almeida Lima, Fernanda Poletto, Renata Vidor Contri, Irene Clemes Kulkamp Guerreiro
Summary: In recent years, there has been a growing interest in the development of paediatric formulations, and nanotechnology has been proposed as a beneficial tool. This review explored the literature on various types of nanostructures for treating paediatric diseases and found that nanotechnology has the potential to enhance therapeutic efficacy, improve drug taste, and enable targeted therapy. The most commonly studied nanostructures were polymeric nanoparticles, lipid-based nanocarriers, and polymeric micelles. Specific tests designed for paediatric formulations included efficacy and safety studies in animal models of paediatric diseases, as well as palatability verification.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Environmental
Kiany de Oliveira Firmino, Francielli Lima Dos Santos, Morgana Souza Marques, Barbara Souza da Costa, Gabriela da Silva Collar, Juliana Caierao, Alexandre Meneghello Fuentefria, Irene Clemes Kulkamp Guerreiro, Renata Vidor Contri
Summary: This study aimed to develop and characterize nanoemulsions and polymeric nanocapsules that contain 5% ozonated sunflower seed oil and have potential activity against skin pathogens. The results showed that these nanometric systems were stable and demonstrated increased antimicrobial efficacy against fungi when compared to the pure ozonated oil.
OZONE-SCIENCE & ENGINEERING
(2023)
Article
Pharmacology & Pharmacy
Francielli Lima dos Santos, Julia Capp Zilles, Andressa Urbano Machado, Morgana Souza Marques, Barbara Souza da Costa, Irene Clemes Kulkamp Guerreiro, Alexandre Meneghello Fuentefria, Renata Vidor Contri
Summary: In this study, Eudragit(R) RS100 nanocapsules containing terbinafine hydrochloride and ozonated sunflower seed oil were developed and characterized. The nanocapsules showed controlled drug release and skin permeation, as well as greater antifungal activity against dermatophyte strains compared to the drug solution.
Article
Materials Science, Ceramics
Catia Liane Ucker, Francielen San Martins Rodrigues, Fabio Calcagno Riemke, Fernando Dal Pont Morisso, Marcio Daldin Teodoro, Valmor R. Mastelaro, Mateus Meneghetti Ferrer, Cristiane Wienke Raubach, Sergio da Silva Cava
Summary: This study demonstrates the synthesis of an orthorhombic Nb2O5 (T) heterostructure coated with low-crystallinity Nb2O5 using the polymeric precursor method. The heterostructure sample exhibited a significant enhancement in photocatalytic performance compared to orthorhombic Nb2O5, achieving complete degradation of RhB within 60 min.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Biomaterials
Fernanda Mendes de Moraes, Jovana Volpato Philippi, Fernanda Belle, Francielly Suzaine da Silva, Fernando Dal Pont Morisso, Debora Rech Volz, Ana Luiza Ziulkoski, Franciane Bobinski, Karine Modolon Zepon
Summary: This study developed powder hemostats based on iota-carrageenan, xyloglucan, l-serine, and tranexamic acid, and investigated their characteristics and performance. The results showed that increasing the tranexamic acid content improved the in vitro biodegradation capacity of the powder hemostats, and resulted in reduced bleeding time and excellent hemocompatibility and antioxidant activity.
BIOMATERIALS ADVANCES
(2022)
Article
Materials Science, Multidisciplinary
Joni Moises Ermel, Sandra Raquel Kunst, Augusto de Freitas Kelsch, Luciane Tais Fuhr, Fernando Dal Pont Morisso, Guilherme Jose Schneider, Claudia Trindade Oliveira, Alexandre da Silva Rocha
Summary: This study aimed to verify the feasibility of using scrap from technical parts as raw material for the manufacture of fashion accessories. The scrap was analyzed for its chemical composition, microstructure, and thermal characteristics, and then melted under pressure to produce components for shoes and accessories. The samples cast using the scrap performed satisfactorily in all tests and, in some cases, even better than the control parts cast with virgin raw material. Therefore, the reuse of scrap represents a possibility of reducing manufacturing costs.
MATERIA-RIO DE JANEIRO
(2022)
Article
Materials Science, Multidisciplinary
Mariana Neis, Ruth Marlene Campomanes Santana, Fernando Dal Pont Morisso
Summary: Improper disposal of tires poses a serious environmental threat, while incorporating tire residues into SEBS thermoplastic elastomer can create economically attractive new materials with improved mechanical properties, suitable for applications such as industrial floors.
MATERIA-RIO DE JANEIRO
(2022)
Article
Multidisciplinary Sciences
Anand Thirupathi, Helen R. Sorato, Paulo R. L. Silva, Adriani P. Damiani, Vanessa M. Andrade, Paulo C. L. Silveira, Renata T. Nesi, Marcos M. S. Paula, Ricardo A. Pinho
Summary: The study found that tau-AuNPs had a significant effect on reducing oxidative stress parameters and increasing the expression of muscle differentiation protein Myf-5 in the overuse group. However, its effect on reducing DNA damage was not significant.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2021)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)