Article
Chemistry, Applied
Seyed Yahya Rahnamaee, Reza Bagheri, Hamed Heidarpour, Manouchehr Vossoughi, Mortaza Golizadeh, Ali Samadikuchaksaraei
Summary: The study designed a double-layer coating assembled onto a nanotube array, which promotes osteoblast cell viability, prolongs antibiotic release, and inhibits bacterial biofilm formation. The synergistic effect of RGO and CH on the biological performance of the surface was investigated.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
S. Kiranmai, Charan Kuchi, Bathinapalta Sravani, Teresa Luczak, Myung Jong Kim, G. Madhavi, Y. Veera Manohara Reddy
Summary: A facile sensing platform using titanium dioxide-reduced graphene oxide nanofibers was developed for the accurate detection of epinephrine in biological fluids and pharmaceutical drugs.
SURFACES AND INTERFACES
(2022)
Article
Engineering, Environmental
Atefeh Mousavi Anjeh, Seyed Reza Nabavi
Summary: In this study, CS/PA6 composite nanofibers were prepared by electrospinning and the addition of GO improved the performance of the composite nanofibers. The results showed that the addition of GO led to the formation of a spider-web-like structure and improved the Young's modulus and thermal degradation resistance of the nanofibers. Furthermore, the prepared composite nanofibers exhibited good adsorption capacity for lead ions.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Environmental Sciences
Esmaeel Sharifi, Rezvan Jamaledin, Fatemeh Familsattarian, Fereshteh Nejaddehbashi, Mitra Bagheri, Mohammad Chehelgerdi, Ehsan Nazarzadeh Zare, Omid Akhavan
Summary: This research evaluated the potential of bioactive chitosan@poly (ethylene oxide)@CuFe2O4 (CS@PEO@CF) nanofibers in wound healing. The nanoparticles showed antibacterial and antioxidant properties and did not adversely affect fibroblast cell viability. The nanofibrous mats promoted cell migration and growth at the wound edge, leading to enhanced wound healing and regeneration of sebaceous glands and hair follicles within the skin.
ENVIRONMENTAL RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Mohammadreza Hasani Azerbaijan, Ehsan Bahmani, Mania Habibi Jouybari, Amir Hassaniazardaryani, Pouya Goleij, Mohammad Akrami, Mohammad Irani
Summary: The study successfully prepared a pH/temperature dual responsive carrier in the form of core-shell nanofibers for controlled release of paclitaxel against A549 lung cancer. Characterization of the synthesized nanofibers was conducted using SEM, TEM, and XRD analysis, with evaluation of drug encapsulation efficiency, drug release, kinetic studies, and compatibility of the nanofibers. In vitro cell viability studies showed promising results for the PTT/CHT combined method in treating lung cancer.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Fahad A. AlAbduljabbar, Sajjad Haider, Fekri Abdulraqeb Ahmed Ali, Abdulaziz A. Alghyamah, Waheed A. Almasry, Raj Patel, Iqbal M. Mujtaba
Summary: In this study, chitosan nanofibers membranes with different characteristics were prepared and analyzed through various spectroscopic and microscopic methods. The incorporation of TiO2 nanoparticles and the changes in surface morphology were confirmed. The higher photocatalytic activity of the Cs_Coa NFs membrane was attributed to a balance between band gap, surface roughness, and surface area.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Engineering, Multidisciplinary
Seyede Mahtab Hosseini, Majid Abdouss, Saeedeh Mazinani, Azim Soltanabadi, Mohammadreza Kalaee
Summary: This study prepared polyvinyl alcohol (PVA) nanofibers containing chitosan nanoparticles and drug-loaded graphene oxide-magnetite nanocomposites for smart wound dressing. The nanofiber membranes showed high water absorption, low degradability, controlled drug release, good antimicrobial properties against gram-positive and gram-negative bacteria, and high compatibility with cells.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Kimiya Hasanbegloo, Solmaz Banihashem, Babak Faraji Dizaji, Sara Bybordi, Nika Farrokh-Eslamlou, Parvaneh Ghaderi-shekhi Abadi, Fariborz Sharifian Jazi, Mohammad Irani
Summary: Liposomes and nanofibers were studied as effective drug delivery systems for anticancer drugs, and three different formulations were investigated for the controlled release of paclitaxel and the treatment of breast cancer. The release behavior, cytotoxicity, and in vivo tumor efficiency were evaluated, and the results showed that liposome-loaded core-shell nanofibers had the best drug release behavior and highest cytotoxicity against breast cancer cells. In vivo experiments also demonstrated the potential effectiveness of these formulations for cancer treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
Konstantinos N. Maroulas, Dimitrios G. Trikkaliotis, Zoi S. Metaxa, Naglaa Abdelall, Abdullah Alodhayb, Ghada A. Khouqeer, George Z. Kyzas
Summary: The study recommends the use of biopolymer-derived aerogels to address oil spills. The aerogels demonstrated high absorption capacity for both water and diesel oil, and they can be effectively used for the oil/water separation process.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Penghui Xia, Hao Li, Yunjing Wang, Jianfeng Wang
Summary: Through a hydrogel processing route, ultrastrong ANF-based nanocomposite films were fabricated with mechanical properties significantly higher than pure ANF films, benefiting from the uniform dispersion of BGO and multiple hydrogen bonding.
APPLIED SURFACE SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Parvaneh Ghaderi Shikhi-Abadi, Mohammad Irani
Summary: The study highlights that chitosan nanofibers prepared by electrospinning method have unique properties suitable for delivering anticancer drugs to treat cancer patients. Chitosan fibers have extensive application prospects in various cancer treatments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Ilaria Silvestro, Clarissa Ciarlantini, Iolanda Francolini, Pierpaolo Tomai, Alessandra Gentili, Chiara Dal Bosco, Antonella Piozzi
Summary: Solid-phase extraction coupled with LC/MS/MS analysis is an effective method for determining organic micropollutants in liquid samples. The use of innovative sorbent materials such as graphene oxide and polysaccharides has shown promise in achieving higher efficiency in isolating and preconcentrating different hydrophilic/hydrophobic pollutants. The prepared chitosan-graphene oxide composite membranes with improved dimensional stability in water, along with the presence of high GO content, exhibited better efficacy in removing various pollutants compared to membranes based solely on chitosan.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Polymer Science
Nasim Afsari, Niloofar Eslahi, Mehdi Varsei, Hajar Ghanbari
Summary: This study aims to produce smart nanocomposite fibers for potential sensing applications using the electrospinning method. Polyvinylpyrrolidone (PVP) and polydiacetylene (PDA) solutions at varying ratios are electrospun, and graphene oxide (GO) is added to enhance the mechanical properties and sensitivity of the fibers. The incorporation of GO leads to a decrease in average fiber diameter and the colorimetric behavior of the fibers changes with temperature and pH, making them potential candidates as sensors.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Ibrahim Abdel Aziz Ibrahim, Abdullah R. Alzahrani, Ibrahim M. Alanazi, Naiyer Shahzad, Imran Shahid, Alaa Hisham Falemban, Mohd Fahami Nur Azlina, Palanisamy Arulselvan
Summary: Our study produced GO-TiO2-chitosan-escin nanocomposites (GTCEnc) and characterized their properties using physical and biological methods. We found that GTCEnc has potential as cancer treatment candidates and demonstrated antibacterial activity. Additional research is needed to evaluate the clinical efficacy of these nanocomposites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Engineering, Chemical
Caique Prado Machado de Oliveira, Inara Fernandes Farah, Konrad Koch, Joreg E. Drewes, Marcelo Machado Viana, Miriam Cristina Santos Amaral
Summary: Membranes modified with nanocomposites offer improved performance in membrane separation processes, with additional advantages such as photocatalytic activity. TiO2-graphene oxide nanocomposites show promise in enhancing membrane hydrophilicity, inducing antimicrobial activity, and reducing fouling potential.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Review
Engineering, Biomedical
Fariborz Sharifianjazi, Azadeh Jafari Rad, Ameneh Bakhtiari, Firoozeh Niazvand, Amirhossein Esmaeilkhanian, Leila Bazli, Milad Abniki, Mohammad Irani, Amirhossein Moghanian
Summary: Cancer, the second leading cause of death globally, is on the rise. Early detection using nanomaterial-based nanobiosensors can effectively enhance treatment outcomes. This review highlights the latest advancements in using nanoparticles for the detection of cancer biomarkers.
BIOMEDICAL MATERIALS
(2022)
Article
Pharmacology & Pharmacy
Mahdi Abasalta, Azadeh Asefnejad, Mohammad Irani, Mohammad Taghi Khorasani, Ahmad Ramazani Saadatabadi
Summary: In this study, N-CMCS/PVA/PCL nanofibers and core-shell nanofibers were prepared using coaxial electrospinning method, and the anticancer drug DOX was successfully loaded into the fibers. The adsorption and controlled release of DOX were compared between the fibers, and the results demonstrated the higher potential of coaxial nanofibers.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Reza Alisani, Navid Rakhshani, Maryam Abolhallaj, Foojan Motevalli, Parvaneh Ghaderi-Shekhi Abadi, Mohammad Akrami, Mohsen Shahrousvand, Fariborz Sharifian Jazi, Mohammad Irani
Summary: In this study, cellulose acetate-based composite nanofibers containing poly (epsilon-caprolactone diol), poly (tetramethylene ether) glycol-polyurethane, and multi-walled carbon nanotubes (CA/PCL-Diol/PTMG-PU/MWCNTs) were prepared and investigated for their adsorption/release properties of doxorubicin (DOX). The results showed that the composite nanofibers exhibited better sustained drug release profiles and synergistic effects on cell death against LNCaP prostate cancer cells.
Article
Nanoscience & Nanotechnology
Mohsen Shahrousvand, Mohsen Hajikhani, Leila Nazari, Amitis Aghelinejad, Mohammad Shahrousvand, Mohammad Irani, Amir Rostami
Summary: The study successfully synthesized pH-sensitive colloidal amphiphilic poly(vinyl alcohol-2-hydroxyethyl methacrylate) (PVA-PHEMA) copolymer nanoparticles, which have potential applications in cancer therapy. The nanoparticles can accept or donate protons in response to environmental pH changes and exhibit favorable drug release kinetics.
Article
Chemistry, Physical
Mahdi Abasalta, Ramin Zibaseresht, Mojtaba Yousefi Zoshk, Masoumeh Foroutan Koudehi, Mohammad Irani, Zahra Hami
Summary: In this study, clarithromycin and zinc oxide nanoparticles were incorporated into chitosan/gelatin/polyurethane core-shell nanofibers. The nanofibers showed antibacterial activity and could be used as wound dressings.
JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
(2022)
Review
Engineering, Chemical
Parvaneh Ghaderi-shekhi Abadi, Mohammad Irani, Leila Roshanfekr Rad
Summary: This review summarizes the application of nanofibers prepared by the electrospinning method as photocatalysts/adsorbents in wastewater treatment techniques. Various nanofiber-heterogeneous catalysts have been developed to enhance the efficiency of these processes. Challenges and future perspectives for the removal of organic/inorganic pollutants from water are also proposed.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Polymer Science
Ehsan Bahmani, Babak Faraji Dizaji, Sam Talaei, Shahnaz Koushkbaghi, Hamid Yazdani, Parvaneh Ghaderi-shekhi Abadi, Mohammad Akrami, Mohsen Shahrousvand, Fariborz Sharifian Jazi, Mohammad Irani
Summary: In this study, paclitaxel, multi-walled carbon nanotubes, and doxorubicin were doped into poly(epsilon-caprolactone)/chitosan/zein core-shell nanofibers to increase their cytotoxicity for breast cancer cells. The synthesized nanofibers showed sustained release of drugs and high biocompatibility, effectively inhibiting tumor growth.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Article
Biochemistry & Molecular Biology
Kimiya Hasanbegloo, Solmaz Banihashem, Babak Faraji Dizaji, Sara Bybordi, Nika Farrokh-Eslamlou, Parvaneh Ghaderi-shekhi Abadi, Fariborz Sharifian Jazi, Mohammad Irani
Summary: Liposomes and nanofibers were studied as effective drug delivery systems for anticancer drugs, and three different formulations were investigated for the controlled release of paclitaxel and the treatment of breast cancer. The release behavior, cytotoxicity, and in vivo tumor efficiency were evaluated, and the results showed that liposome-loaded core-shell nanofibers had the best drug release behavior and highest cytotoxicity against breast cancer cells. In vivo experiments also demonstrated the potential effectiveness of these formulations for cancer treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Textiles
Leila Mohammad Taghizadeh Kashani, Mohammad Mahdi Ahmadian-Attari, Mohammad Irani
Summary: The combination of plant-derived agents with chemotherapy drugs in PCL nanofibers enhances drug cytotoxicity in cancer cells and improves biocompatibility in normal cells. CALRS and DOX were incorporated into PCL nanofibers, which were characterized using various techniques. The nanofibers exhibited antibacterial, antiparasitic, and anticancer activities. DOX release from the nanofibers followed the Korsmeyer-Peppas model. The DOX and CALRS dual agents-loaded nanofibers showed superior antibacterial activity and anticancer activity compared to pure DOX, CALRS, and DOX loaded-PCL nanofibers.
JOURNAL OF THE TEXTILE INSTITUTE
(2023)
Review
Nanoscience & Nanotechnology
Parvaneh GhaderiShekhiAbadi, Mohammad Irani, Mohammad Noorisepehr, Ali Maleki
Summary: Infectious diseases, such as SARS-CoV-2, Influenza, HIV, and Ebola, continue to cause significant mortality worldwide. The lack of proper vaccines, drugs, therapies, and detection methods for some infectious diseases presents a major challenge. Magnetic materials have emerged as active sensors/biosensors for detecting viral, bacterial, and plasmid agents. This review discusses the recent applications of magnetic materials in biosensors for infectious virus detection and addresses future trends and perspectives.
Article
Engineering, Environmental
Shaghayegh Takmilsefat Najjari, Azadeh Asefnejad, Parvaneh Ghaderi Shikhi Abadi, Nahid Hasnzadeh Nemati, Mohammad Irani
Summary: Nanofibers prepared by electrospinning process were loaded with 5-Fluorouracil and Paclitaxel anticancer drugs and investigated for their controlled release against MCF-7 breast cancer cells. The tri-layered nanofibers showed higher drug loading efficiency and shorter controlled release time compared to mono-layered nanofibers. The results demonstrated that tri-layered nanofibers are a more efficient carrier for drug loading and treatment of MCF-7 breast cancer cells.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Chemistry, Physical
Azin Abdollahi, Zahra Ansari, Mohammad Akrami, Ismaeil Haririan, Simin Dashti-Khavidaki, Mohammad Irani, Mojtaba Kamankesh, Emad Ghobadi
Summary: An extended-release tablet of tacrolimus as once-daily dosing was fabricated using 3D printing technology. The tablet was developed by combining two 3D-printing methods and met the USP requirements for weight variation, friability, hardness, assay, and content uniformity. SEM analysis showed smooth surfaces with multiple deposited layers, and there was no decomposition of the polymer and drug observed at the printing temperature. The novel 3D-printed tablet with tailored dosing and specific kinetic release has the potential to be used for personalized medicine.
Article
Chemistry, Multidisciplinary
Shahnaz Koushkbaghi, Hamta Arjmand Kermani, Sana Jamshidifard, Hamed Faramarzi, Mina Khosravi, Parvaneh Ghaderi-shekhi Abadi, Fariborz Sharifian Jazi, Mohammad Irani
Summary: In this study, UiO-66-NH2 and UiO-66-NH2/TiO2 MOFs were loaded into PAN nanofibers supported on PES. The effects of pH, initial concentration, and time on the removal efficiency of phenol and Cr(vi) were investigated under visible light irradiation. The best performance was achieved with UiO-66-NH2/TiO2 MOF 5 wt% loaded-PES/PAN nanofibrous membranes at a temperature of 25 degrees C and pH of 3. The synthesized MOFs-loaded nanofibrous membranes demonstrated high capability for the removal of Cr(vi) ions and phenol molecules from water.
Review
Engineering, Environmental
Parvaneh Ghaderi Shikhi Abadi, Mohammad Irani
Summary: This article reviews the wide application of nanotechnology-based drug delivery processes, discusses various pharmaceutical carriers, and explores the mechanisms of action of MOFs/drug formulations in cancer therapy. It also highlights the synthesis approaches of MOFs/NFs formulations and their applications in antibacterial activity, tissue engineering, and cancer therapy. The challenges and future opportunities of MOFs/NFs carriers in human health are also addressed in this review.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Mohammad Irani, Sina Mohammadrezaei Nodeh
Summary: This study investigates the capability of composite and core-shell nanofibers for targeted delivery of anticancer drugs in lung cancer treatment. The results demonstrate that the simultaneous loading of CMPT and PTX anticancer drugs and Au nanoparticles in core-shell nanofibers is more beneficial for lung cancer treatment.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
