Review
Engineering, Biomedical
Chunlei Zhu, Jichuan Qiu, Stavros Thomopoulos, Younan Xia
Summary: The translation of functionally graded attachment during tendon-to-bone repair process is crucial for successful healing. Biomimetic scaffolds mimicking the unique features of native tendon-to-bone attachment show great promise in enhancing the healing process. Recent efforts in designing and evaluating gradated scaffolds based on electrospun nanofiber mats and inverse opal structures have shown potential for augmenting tendon-to-bone repair.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Chemistry, Physical
Huiling Zhong, Jun Huang, Jun Wu, Jianhang Du
Summary: Electrospun nanofibers are versatile and widely used in tissue engineering, mimicking the extracellular matrix and human tissue structures, suitable for various drug carriers and different functional needs.
Article
Medicine, Research & Experimental
SooJung Chae, Jiyoung Hong, Hanjun Hwangbo, GeunHyung Kim
Summary: Spheroids are complex cellular aggregates that mimic real-world environments and are important in tissue engineering for replacing two-dimensional cell cultures. With or without scaffolds, spheroids can replicate tissue physiological activities and the complex geometry of three-dimensional tissues.
Review
Polymer Science
Sandya Shiranthi Athukorala, Tuan Sang Tran, Rajkamal Balu, Vi Khanh Truong, James Chapman, Naba Kumar Dutta, Namita Roy Choudhury
Summary: Electrically conductive hydrogels (ECHs) are a promising class of biomaterials for a wide range of biomedical applications, with 3D printing being an advanced technique for rapid fabrication of future biomedical implants and devices with versatile designs and adjustable functionalities. This review provides an overview of state-of-the-art 3D printed ECHs, discussing mechanisms of electrical conductivity, design considerations, and recent advances in formulation of 3D printable bioinks. Challenges and limitations of 3D printing of ECHs are identified, along with highlighting new 3D printing-based hybrid methods for selective deposition and controlled nanostructure fabrication.
Article
Polymer Science
Ricardo Donate, Ruben Paz, Alvaro Quintana, Pablo Bordon, Mario Monzon
Summary: The incorporation of ceramic additives is a commonly used strategy to improve polymer-based scaffolds for bone regeneration. This study presents a method to coat polylactic acid (PLA) scaffolds with calcium carbonate (CaCO3) particles, resulting in improved mechanical properties and surface characteristics. The coated scaffolds showed potential for bone tissue engineering applications.
Article
Engineering, Biomedical
Fatemeh Hejazi, Shadab Bagheri-Khoulenjani, Nafiseh Olov, Darya Zeini, Atefeh Solouk, Hamid Mirzadeh
Summary: This study introduces novel 3D-functionality graded nanofibrous scaffolds for osteoregeneration and chondral regeneration, showing promising potential for treating osteochondral defects. The scaffolds demonstrated improved physicochemical properties and biological performance, indicating a potential application in tissue engineering for bone and cartilage growth.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Materials Science, Multidisciplinary
Ozlem Canpolat, Aykut Canakci, Fatih Erdemir
Summary: The performance of biomedical implants has been the focus of research. Functionally graded materials (FGM) have the potential to improve implant performance by mimicking bone structure. In this study, SS316L/Al2O3 FGM was successfully fabricated using the powder metallurgy technique, and its microstructure, corrosion resistance, and mechanical and bioactivity properties were investigated.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Materials Science, Multidisciplinary
Susheem Kanwar, Sanjairaj Vijayavenkataraman
Summary: In the field of tissue engineering, various designs have been used for bone biomimicry, but there are some limitations such as lack of localized porosity control and stress concentration. This paper proposes a novel method for generating stochastic structures with locally tunable porosity and anisotropically varying mechanical properties. The method not only allows for computationally inexpensive and non-complex generation of stochastic structures, but also enables controlled porosity gradient along three different axes. A comparison of mechanical properties between the generated scaffold and the rabbit microstructure shows significant variations, indicating the need for further multi-property optimization.
MATERIALS & DESIGN
(2022)
Review
Biochemistry & Molecular Biology
Teresa Aditya, Jean Paul Allain, Camilo Jaramillo, Andrea Mesa Restrepo
Summary: Bacterial cellulose is a naturally occurring polysaccharide with various biomedical applications. It possesses remarkable biocompatibility and mechanical properties, making it suitable for tissue replacement. This review discusses the structure, mechanical properties, and characterization techniques of bacterial cellulose. It also explores the functionalization and surface modification methods to enhance its functionality.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Polymer Science
Shuo Chen, Yihan Wang, Lei Yang, Chengzhen Chu, Shichun Cao, Zhao Wang, Jiajia Xue, Zhengwei You
Summary: In this review, the recent progress in synthesis, process technologies, and biomedical applications of biodegradable elastomers is summarized. The emphasis is on the molecular design and processing strategies of biodegradable polyesters and polyurethanes, as well as the newly developed functionalities in biomedical applications. Future research directions, challenges, and potential solutions are discussed.
PROGRESS IN POLYMER SCIENCE
(2023)
Review
Chemistry, Multidisciplinary
Oystein Arlov, Dominic Rutsche, Maryam Asadi Korayem, Ece Ozturk, Marcy Zenobi-Wong
Summary: Sulfated polysaccharides play central roles in biological functions, and engineered sulfated polysaccharides exhibit novel and augmented biological properties through facilitating interactions with other macromolecules.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Engineering, Biomedical
Sophie Wendels, Luc Averous
Summary: Polyurethanes (PUs) have a wide range of applications in the biomedical field, showing advanced properties such as controlled biotic and abiotic degradation. They possess precise tissue biomimicking structures and shape-recovery properties, making them suitable for cell adhesion, proliferation, and differentiation. While substitution of fossil-based materials for biomedical implants is slowly improving, achieving higher renewable contents is still necessary for biobased certifications.
BIOACTIVE MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Wei Xu, Aihua Yu, Yu Jiang, Yageng Li, Ce Zhang, Harsh-preet Singh, Bowen Liu, Chenjin Hou, Yun Zhang, Shiwei Tian, Jiazhen Zhang, Xin Lu
Summary: Functionally graded porous titanium scaffolds were designed and fabricated, showing high biocompatibility and mechanical properties, making them suitable for dental implants.
MATERIALS & DESIGN
(2022)
Article
Materials Science, Biomaterials
Chenjin Hou, Yitong Liu, Wei Xu, Xin Lu, Lijia Guo, Yi Liu, Shiwei Tian, Bowen Liu, Jiazhen Zhang, Cuie Wen
Summary: Graded porous titanium scaffolds with desired mechanical properties and biocompatibility are found to be suitable for dental implants and bone tissue engineering applications.
BIOMATERIALS ADVANCES
(2022)
Review
Chemistry, Physical
Yujin Kim, Kuk Hui Son, Jin Woo Lee
Summary: Utilizing auxetic structures with negative Poisson's ratio for tissue engineering and biomedical applications is a promising area that has not been extensively studied yet. The fabrication of these structures using additive manufacturing and the cultivation of various cells have shown potential for tissue regeneration through cell proliferation, alignment, and differentiation. Further research on auxetic structures at the cellular level could lead to breakthroughs in tissue reconstruction and improved biomedical devices.
Article
Materials Science, Ceramics
Clemence Petit, Sylvain Meille, Eric Maire, Laurent Gremillard, Jerome Adrien, Grace Y. Lau, Antoni P. Tomsia
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2017)
Article
Materials Science, Multidisciplinary
Clemence Petit, Eric Maire, Sylvain Meille, Jerome Adrien
MATERIALS & DESIGN
(2017)
Article
Polymer Science
Rossella Arrigo, Diego Antonioli, Massimo Lazzari, Valentina Gianotti, Michele Laus, Laura Montanaro, Giulio Malucelli
Article
Materials Science, Biomaterials
Clemente Petit, Jean-Marc Tulliani, Solene Tadier, Sylvain Meille, Jerome Chevalier, Paola Palmero
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Materials Science, Ceramics
Bartolomeo Coppola, Paola Palmero, Laura Montanaro, Jean-Marc Tulliani
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2020)
Article
Materials Science, Ceramics
Bartolomeo Coppola, Caroline Tardivat, Stephane Richaud, Jean-Marc Tulliani, Laura Montanaro, Paola Palmero
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2020)
Article
Materials Science, Multidisciplinary
J. Croquesel, C. Meunier, C. Petit, F. Valdivieso, S. Pillon, A. C. Robisson, J. Martinez, F. Lemont
Summary: This paper presents the development of an innovative instrumented and automated 2.45GHz multimode microwave cavity for sintering nuclear fuels, achieving high-density UO2 pellets through precisely controlled sintering cycles.
MATERIALS & DESIGN
(2021)
Article
Materials Science, Ceramics
C. Petit, C. Meunier, F. Valdivieso, J. Croquesel, S. Pillon, A. C. Robisson, J. Martinez, F. Lemont
Summary: The study demonstrated that high-density sintering of uranium dioxide pellets can be achieved through hybrid and direct microwave heating. Experimental results showed that thermal cycles under hybrid conditions produced grain sizes and density values close to conventional sintering, while direct microwave heating required the assistance of a susceptor for effective heating.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Ceramics
Nouhaila Khalile, Clemence Petit, Christophe Meunier, Francois Valdivieso
Summary: This study investigates the effects of different sintering cells on the microstructure and densification of Al2O3 and 3Y-TZP. The sintering cell containing both mullite tube and SiC susceptor results in higher final densities, lower densification temperatures, and better microstructure homogeneity. However, the performance of Al2O3 and 3Y-TZP varies with different sintering cells, which may be attributed to the difference in dielectric properties and the influence of the sintering cell.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Nouhaila Khalile, Christophe Meunier, Clemence Petit, Francois Valdivieso, Bartolomeo Coppola, Paola Palmero
Summary: Nowadays, ceramic parts with solid and complex shapes can be produced using rapid and efficient shaping and sintering techniques. This study utilized Digital Light Processing (DLP) for shaping and conventional (CV) and microwave (MW) sintering to produce 3mol% yttria stabilized zirconia (3Y-TZP) dense and lattice parts. MW sintering of 3Y-TZP samples with different heating rates and CV sintering were conducted, resulting in high final densities for both dense and lattice MW-sintered samples.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Justin Chassagne, Clemence Petit, Christophe Meunier, Francois Valdivieso
Summary: This study compared the effects of conventional and microwave heating on the formation of magnesium and zinc aluminate spinels, finding that spinel phases could be obtained more rapidly under microwave thermal cycles. The presence of ZnO as a microwave absorbent was beneficial for material interactions, but a SiC susceptor was necessary for heating in all considered mixtures.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Education, Scientific Disciplines
Maria Giulia Ballatore, Laura Montanaro, Anita Tabacco
INTERNATIONAL JOURNAL OF ENGINEERING PEDAGOGY
(2019)
Article
Materials Science, Ceramics
Laura Montanaro, Paola Palmero
CERAMICS-SWITZERLAND
(2019)
