Characterization of the mechanical properties of cancer cells in 3D matrices in response to collagen concentration and cytoskeletal inhibitors

The extracellular matrix in breast cancer

(2016) Jacob Insua-Rodríguez et al.   ADVANCED DRUG DELIVERY REVIEWS

Extracellular matrix stiffness causes systematic variations in proliferation and chemosensitivity in myeloid leukemias

(2016) Jae-Won Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro three dimensional culture of hepatocellular carcinoma to measure prognosis and responsiveness to chemotherapeutic agents

(2016) Brad Shrum et al.   HEPATOBILIARY SURGERY AND NUTRITION

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

(2016) Marta Cavo et al.   Scientific Reports

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Probing the Stochastic, Motor-Driven Properties of the Cytoplasm Using Force Spectrum Microscopy

(2014) Ming Guo et al.   CELL

How Taxol/paclitaxel kills cancer cells

(2014) Beth A. Weaver   MOLECULAR BIOLOGY OF THE CELL

High-Speed Single-Particle Tracking of GM1 in Model Membranes Reveals Anomalous Diffusion due to Interleaflet Coupling and Molecular Pinning

(2014) Katelyn M. Spillane et al.   NANO LETTERS

Force fluctuations in three-dimensional suspended fibroblasts

(2014) F. Schlosser et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Three-Dimensional In Vitro Co-Culture Model of Breast Tumor using Magnetic Levitation

(2014) Hamsa Jaganathan et al.   Scientific Reports

Impact of Dimensionality and Network Disruption on Microrheology of Cancer Cells in 3D Environments

(2014) Michael Mak et al.   PLoS Computational Biology

Tissue mechanics and fibrosis

(2013) Rebecca G. Wells   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

A physical sciences network characterization of non-tumorigenic and metastatic cells

(2013)   Scientific Reports

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

(2012) G M A Ajabnoor et al.   Cell Death & Disease

How Matrix Properties Control the Self-Assembly and Maintenance of Tissues

(2011) Cynthia A. Reinhart-King   ANNALS OF BIOMEDICAL ENGINEERING

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Tumor microenvironment and progression

(2011) Harold F. Dvorak et al.   JOURNAL OF SURGICAL ONCOLOGY

Five challenges to bringing single-molecule force spectroscopy into living cells

(2011) Yves F Dufrêne et al.   NATURE METHODS

Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel

(2011) Renaud Poincloux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of mechanical signaling in development and disease

(2010) P. A. Janmey et al.   JOURNAL OF CELL SCIENCE

Sensing tension

(2010) Andrew D. Doyle et al.   NATURE

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

The Role of the Microenvironment in Mammary Gland Development and Cancer

(2010) K. Polyak et al.   Cold Spring Harbor Perspectives in Biology

Particle-Tracking Microrheology of Living Cells: Principles and Applications

(2009) Denis Wirtz   Annual Review of Biophysics

Extracellular Matrix Stiffness and Architecture Govern Intracellular Rheology in Cancer

(2009) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone

(2009) S. Liu et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

How do anti-mitotic drugs kill cancer cells?

(2009) K. E. Gascoigne et al.   JOURNAL OF CELL SCIENCE

Rheology of the Cytoskeleton

(2008) Mohammad R.K. Mofrad   Annual Review of Fluid Mechanics

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

3D cell culture opens new dimensions in cell-based assays

(2008) Bradley A. Justice et al.   DRUG DISCOVERY TODAY

Anomalous dynamics of cell migration

(2008) P. Dieterich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA