期刊
INORGANICA CHIMICA ACTA
卷 480, 期 -, 页码 1-15出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ica.2018.04.038
关键词
Hydrazone; Biological activity; X-ray; DFT; Theoretical IR
Novel hydrazone 2-(2-((1E,2E)-2-(2-phenylhydrazineylidene)propylidene)hydrazineyl)pyridine and its nickel(II) and copper(II) complexes have been synthesized and characterized. The ligand (H(2)PGl) was prepared by the condensation reaction of 1-(2-phenylhydrazineylidene) propan-2-one and 2-hydrazinopyridine. The crystal structure of Ni(II) complex was determined. In both Ni(II) and Cu(II) complexes, H(2)PGl act as a neutral tridentate ligand forming two fused five-membered chelation rings through NNN set of donor atoms. Octahedral geometry is proposed for both chelates as illustrated in both magnetic and spectroscopic data. ESR spectroscopy was performed for Cu(II) complex which exhibited a considerable Cu-Cu interaction and harmonize directly with measured magnetic moment. The molecular modeling structures were optimized and showed the bond length, bond angle, reactivity, MEP and atomic charges for all the title frameworks. Hypothetical infrared intensities and H-1 NMR of H(2)PGl was estimated on the basis of DFT scheme. A comparison of the experimental and theoretical data was very useful in creating correct assignments and understanding the basic chemical shift. Biological activity of the synthesized compounds were investigated versus some Gram positive, Gram negative bacteria and some fungal strains. Also, the antitumor activity was investigated. (C) 2018 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据