Article
Gastroenterology & Hepatology
Christopher V. Almario, Lawrence Kogan, Welmoed K. van Deen, Frank I. Scott, Siddharth Singh, Jason K. Hou, Donald Lum, Humberto Aguilar, John Betteridge, Ann Flynn, Mark Gerich, Lia Kaufman, Mark C. Mattar, Carrie Mize, Arthur Ostrov, Samir A. Shah, Ziad Younes, S. Alandra Weaver, Caren Heller, Corey A. Siegel, Gil Y. Melmed
Summary: The implementation of clinical care process changes using a Collaborative approach has been associated with lower annual costs for patients with inflammatory bowel disease, providing overall cost savings. Further research is needed to determine the most effective interventions and the sustainability of these cost savings.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Biochemistry & Molecular Biology
Pierre A. Geoffroy, Maria A. Oquendo, Philippe Courtet, Carlos Blanco, Mark Olfson, Hugo Peyre, Michel Lejoyeux, Frederic Limosin, Nicolas Hoertel
Summary: Research suggests that sleep disturbances are associated with an increased risk of suicide, independently of psychopathology. A study using structural equation modeling found that sleep complaints such as trouble falling asleep, early morning awakening, and hypersomnia are significantly associated with an increased risk of attempting suicide, with effects exerted through a general sleep complaints factor rather than individual complaints. This highlights the importance of including sleep disturbances in suicide risk assessments as potential targets for intervention to reduce the risk of suicidal behaviors.
MOLECULAR PSYCHIATRY
(2021)
Article
Gastroenterology & Hepatology
Hanna Blaney, Peter Vu, Antony Mathew, Robin Snelling, Julie England, Camille Duong, Kendall Hammonds, Christopher Johnson
Summary: The presence of anemia in patients with IBD is associated with increased healthcare resource utilization, with more severe anemia linked to higher utilization and costs. Treating anemia is not associated with decreased overall utilization or costs, suggesting a need for further research on this relationship.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Emir Tulumovic, Nermin Salkic, Denijal Tulumovic
Summary: A study was conducted to review the epidemiology of inflammatory bowel disease (IBD) in the Tuzla Canton of Bosnia-Herzegovina over a 10-year period. The findings showed that trends in the incidence and prevalence of IBD in the region were similar to Eastern European averages, although there were significant epidemiological differences within geographically close and demographically similar areas.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Christy Riggott, Keeley M. Fairbrass, Christopher J. Black, David J. Gracie, Alexander C. Ford
Summary: Using latent class analysis, this study identified novel clusters of patients with inflammatory bowel disease (IBD) and found that patients with higher gastrointestinal and psychological symptoms were at a higher risk of adverse disease outcomes and were also high-volume users of healthcare.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Padhmanand Sudhakar, Judith Wellens, Bram Verstockt, Marc Ferrante, Joao Sabino, Severine Vermeire
Summary: Inflammatory bowel disease (IBD) is a global disease that affects the gastrointestinal tract and also has an impact on the mental and emotional well-being of patients. Despite medical advancements, only a third of diagnosed patients achieve short to medium-term remission. Therefore, some patients might resort to complementary and alternative approaches to manage their symptoms. This study reviews the efficacy of these approaches and proposes a patient-centric clinical care model and recommendations.
Article
Nutrition & Dietetics
Fernanda Cristofori, Fulvio Salvatore D'Abramo, Vincenzo Rutigliano, Vanessa Nadia Dargenio, Stefania Castellaneta, Domenico Piscitelli, Davide De Benedittis, Flavia Indrio, Lidia Celeste Raguseo, Michele Barone, Ruggiero Francavilla
Summary: The prevalence of esophageal eosinophilia and eosinophilic esophagitis in children with celiac disease is low. Routine esophageal biopsies are not recommended unless clinically indicated.
Article
Environmental Sciences
Stephen K. Van den Eeden, Matthew H. E. M. Browning, Douglas A. Becker, Jun Shan, Stacey E. Alexeeff, G. Thomas Ray, Charles P. Quesenberry, Ming Kuo
Summary: This study found a significant inverse association between residential green cover and direct healthcare costs. Higher levels of green cover were associated with lower costs, mainly driven by reductions in hospitalization and emergency department visits. Individuals living in areas with the highest green cover had significantly lower healthcare costs compared to those living in areas with the lowest green cover.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Nursing
Mikko Harma, Rahman Shiri, Jenni Ervasti, Kati Karhula, Jarno Turunen, Aki Koskinen, Annina Ropponen, Mikael Sallinen
Summary: This study investigated the utilization of national recommendations in shift scheduling software and examined whether the use of the tool led to changes in working hour characteristics in line with the recommendations. The findings showed that one fifth of the employees continuously used the evaluation tool and there were several changes in working hour characteristics associated with its use.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Gastroenterology & Hepatology
Asa Everhov, Jonas Soederling, Gustaf Befrits, Hamed Khalili, Gabriella Broems, Martin Neovius, Johan Askling, Jonas F. Halfvarson, Jonas Ludvigsson, Ola Olen, SWIBREG Study Group
Summary: This study assessed the costs of prevalent Crohn's disease (CD) or ulcerative colitis (UC) patients in Sweden from 2007 to 2020, including productivity losses. The study found that in recent years, the costs of patients mainly came from healthcare costs, rather than productivity losses. Particularly, the use of biologics contributed to the increase in healthcare costs.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Izabela Zubrzycka, Kaleb Bogale, August Stuart, Melissa Cesaire, Vonn Walter, Shannon Dalessio, Andrew Tinsley, Emmanuelle Williams, Kofi Clarke, Matthew D. Coates
Summary: This study found that abdominal pain was the only clinical variable predictive of future healthcare resource utilization in inflammatory bowel disease (IBD) patients, highlighting the importance of regularly screening for and effectively treating abdominal pain in IBD.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Environmental Sciences
Shuduo Zhou, Pengfei Chai, Xuejie Dong, Zhisheng Liang, Zongming Yang, Junxia Li, Guigen Teng, Shengzhi Sun, Ming Xu, Zhi-Jie Zheng, Jianbing Wang, Zhenyu Zhang, Kun Chen
Summary: This study investigated the associations of metal elements and disinfectants in drinking water with the risk of inflammatory bowel disease (IBD) and assessed the influence of diet on these associations. It found that increased concentrations of manganese, mercury, selenium, sulfur tetraoxide, chlorine, and nitrate nitrogen were associated with a higher risk of IBD, while zinc and fluorine were inversely associated with IBD risk. Stronger associations were observed in certain subgroups, and diets had a moderating effect on the associations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Alexander S. Qian, Nghia H. Nguyen, Jessica Elia, Lucila Ohno-Machado, William J. Sandborn, Siddharth Singh
Summary: Frailty is independently associated with higher mortality and burden of hospitalization in patients with IBD; infections are the leading cause of hospitalization. Frailty should be considered in treatment approach, especially in older patients with IBD.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Vipul Yadav, Yang Mai, Laura E. McCoubrey, Yasufumi Wada, Motoyasu Tomioka, Satofumi Kawata, Shrikant Charde, Abdul W. Basit
Summary: The study demonstrates that 5-ALA has potential not only in treating gliomas but also inflammatory diseases, particularly inflammatory bowel disease. Through in vivo and ex vivo experiments, it was shown that 5-ALA is stable in the colon and can effectively improve colonic inflammation, increase heme oxygenase-1 levels, and reduce proinflammatory cytokines. This suggests that 5-ALA could be a promising addition to current IBD treatments with potential for targeted colonic delivery.
Article
Medicine, General & Internal
Sengul Beyaz, Erdem Akbal
Summary: This study investigated circulating levels of nesfatin-1 in patients with inflammatory bowel diseases (IBD), showing significantly elevated levels during active disease periods with good diagnostic value for IBD. Nesfatin-1 could serve as an additional inflammatory marker for the diagnosis of IBD.
POSTGRADUATE MEDICAL JOURNAL
(2022)
