Article
Peripheral Vascular Disease
Sadeer G. Al-Kindi, Robert D. Brook, Udayan Bhatt, Michael Brauer, William C. Cushman, Heidi A. Hanson, John Kostis, James P. Lash, Robert Paine, Kalani L. Raphael, Stephen Rapp, Leonardo Tamariz, Jackson T. Wright, Sanjay Rajagopalan
Summary: This study examined the impact of fine particulate matter (PM2.5) exposure on cardiovascular events in the context of intensive blood pressure lowering intervention. The results showed that the benefits of intensive blood pressure lowering on cardiovascular events were greater in patients exposed to higher levels of PM2.5.
Article
Environmental Sciences
Daniel A. Enquobahrie, James MacDonald, Michael Hussey, Theo K. Bammler, Christine T. Loftus, Alison G. Paquette, Nora Byington, Carmen J. Marsit, Adam Szpiro, Joel D. Kaufman, Kaja Z. LeWinn, Nicole R. Bush, Frances Tylavsky, Catherine J. Karr, Sheela Sathyanarayana
Summary: This study identified an association between prenatal exposure to PM2.5 and placental gene expression, particularly in the first half of pregnancy. Offspring sex may also play a role in modulating this association, with a positive correlation observed in males and a negative correlation in females.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Huiyu Wang, Jiajianghui Li, Hengyi Liu, Fuyu Guo, Tao Xue, Tianjia Guan, Jiwei Li
Summary: The study found that maternal exposure to PM2.5 is significantly associated with an increased risk of spontaneous pregnancy loss, with advanced maternal age potentially weakening this association, and the association being nonsignificant for unintended pregnancies.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Qi Sun, Yuanmei Chen, Fang Ye, Jing Liu, Die Liu, Bo Ao, Qin Hui, Qi Zhang
Summary: This study aimed to investigate the association between preconception exposure to ambient particulate matter (PM) and hypothyroidism. The results showed that exposure to PM2.5 and PM10 during the 60-day period before the last menstrual period month, 30-day period before the last menstrual period month, and last menstrual period was associated with an increased risk of hypothyroidism.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Toxicology
Nicholas L. Drury, Toriq Mustapha, Ross A. Shore, Jiayun Zhao, Gus A. Wright, Aline Rodrigues Hoffmann, Susanne U. Talcott, Annette Regan, Robert M. Tighe, Renyi Zhang, Natalie M. Johnson
Summary: Research suggests that pregnant women exposed to ultrafine particles during pregnancy may experience abnormal immune responses to influenza, increasing the severity of infection.
PARTICLE AND FIBRE TOXICOLOGY
(2023)
Article
Engineering, Environmental
Shuman Li, Bin Liu, Yongjie Liu, Yu-Qiang Ding, Jun Zhang, Liping Feng
Summary: This study found that exposure to particulate matter (PM) during pregnancy did not significantly impact the birth outcomes of mice. However, it did affect the growth trajectories of offspring after birth in a dose- and fetal sex-dependent manner.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Article
Environmental Sciences
Amanda J. Goodrich, Michael J. Kleeman, Daniel J. Tancredi, Yunin J. Ludena, Deborah H. Bennett, Irva Hertz-Picciotto, Rebecca J. Schmidt
Summary: This study aimed to evaluate the association between prenatal and early postnatal exposure to multiple air pollutants and the risk of autism spectrum disorder (ASD). The results indicated that exposure to PM0.1 and PM2.5-10 may be associated with an increased risk of ASD. Additionally, prenatal O3 exposure and exposure to PM0.1 in the second year of life may also increase the risk of ASD.
ENVIRONMENTAL RESEARCH
(2024)
Article
Cell Biology
Kelly J. Brunst, Hsiao-Hsien Leon Hsu, Li Zhang, Xiang Zhang, Kecia N. Carroll, Allan Just, Brent A. Coull, Itai Kloog, Robert O. Wright, Andrea A. Baccarelli, Rosalind J. Wright
Summary: This study found that prenatal exposure to PM2.5 particulate matter, especially during the mid-to-late pregnancy period, is associated with an increased mitochondrial mutational load in the placenta, particularly among genes encoding NADH dehydrogenase and subunits of ATP synthase. The strongest associations were observed in participants of African ancestry, indicating a need for further research on the role of mitochondrial genetics in offspring development and emerging disease disparities.
Article
Environmental Sciences
Huizhong Shen, Boyu Liu, Yilin Chen, Xi Zhu, Xiao Yun, Wenjun Meng, Cengxi Lu, Guofeng Shen, Yongtao Hu, Armistead G. Russell, Kirk R. Smith, Shu Tao
Summary: The popularity of facemasks has increased in northern China due to severe air pollution. While wearing facemasks can reduce exposure to particulate matter, the protection is limited as people spend most of their time indoors. Installing indoor air purifiers is a more effective strategy for long-term protection against particulate matter exposure.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Environmental Sciences
Mingqing Zhao, Ziyuan Xu, Qianqian Guo, Yong Gan, Qi Wang, Jun-an Liu
Summary: The meta-analysis revealed a significant positive correlation between long-term PM2.5 exposure and the risks of hypertension incidence and prevalence, with higher levels of PM2.5 concentration leading to an increased risk of hypertension.
ENVIRONMENTAL RESEARCH
(2022)
Article
Hospitality, Leisure, Sport & Tourism
Qiong Liu, Keyong Huang, Fengchao Liang, Xueli Yang, Jianxin Li, Jichun Chen, Xiaoqing Liu, Jie Cao, Chong Shen, Ling Yu, Yingxin Zhao, Ying Deng, Ying Li, Dongsheng Hu, Xiangfeng Lu, Yang Liu, Dongfeng Gu, Fangchao Liu, Jianfeng Huang
Summary: This study found an interaction between the benefits of regular physical activity and exposure to air pollution in highly polluted regions on hypertension risk. Regular physical activity was associated with a reduced risk of hypertension only among participants with low PM2.5 exposure.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2022)
Article
Medicine, General & Internal
Eun-jung Koo, Jin-Gon Bae, Eun Jung Kim, Yong-Hoon Cho
Summary: Exposure to PM2.5 during pregnancy, especially in the second trimester, has been found to be correlated with congenital anomalies in neonates. Continuous exposure to high PM2.5 concentrations during pregnancy could significantly increase the risk of neonatal anomalies, despite adjusting for maternal factors.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Environmental Sciences
Zengjing Liu, Adam A. Szpiro, Tsegaselassie Workalemahu, Michael T. Young, Joel D. Kaufman, Daniel A. Enquobahrie
Summary: This study found associations between PM2.5 exposure and gestational weight gain and birth weight, which may be affected by exposure window and pre-pregnancy BMI. Further exploration of these associations is needed to better understand their impact on maternal and child health outcomes.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Joao Xavier Santos, Pedro Sampaio, Celia Rasga, Hugo Martiniano, Clarissa Faria, Catia Cafe, Alexandra Oliveira, Frederico Duque, Guiomar Oliveira, Lisete Sousa, Ana Nunes, Astrid Moura Vicente
Summary: This study examined the association between early-life exposure to air pollutants and clinical severity of Autism Spectrum Disorder (ASD) in children. The results showed that exposure to high levels of PM2.5 and PM10 during the first trimester of pregnancy was associated with higher clinical severity, and exposure to PM2.5 and PM10 during the full pregnancy and third trimester was also associated with higher clinical severity.
ENVIRONMENTAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Ahmad Badeenezhad, Iman Parseh, Ali Veisi, Saeid Rostami, Mousa Ghelichi-Ghojogh, Gholamreza Badfar, Fariba Abbasi
Summary: This study aimed to evaluate the effect of short-term exposure to heavy metals (HM) extracted from PM10 on cardiovascular biomarkers (CB) in workers' population in an outdoor space located in southern Iran during a dust storm. The concentration of PM10 and extracted HM such as Cr, As, and Cd was higher than the WHO/EPA standards in dust storms and they increased the CB and blood pressure significantly. Moreover, the levels of fibrinogen, blood pressure, and TNF-alpha in dust storms were higher than in normal conditions, indicating a potential risk for the residents in the southern regions of Iran.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Ruth-Alma Turkson-Ocran, Kathryn Foti, Anika L. Hines, Debora Kamin Mukaz, Hyunju Kim, Samantha Martin, Anum Minhas, Faye L. Norby, Oluwabunmi Ogungbe, Alexander C. Razavi, Mary R. Rooney, Elisabeth L. P. Sattler, Jewel Scott, Alvin G. Thomas, Curtis Tilves, Amelia S. Wallace, Frances M. Wang, Mingyu Zhang, Pamela L. Lutsey, Kristie J. Lancaster
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Behavioral Sciences
Irva Hertz-Picciotto, Susan A. Korrick, Christine Ladd-Acosta, Margaret R. Karagas, Kristen Lyall, Rebecca J. Schmidt, Anne L. Dunlop, Lisa A. Croen, Dana Dabelea, Julie L. Daniels, Cristiane S. Duarte, M. Daniele Fallin, Catherine J. Karr, Barry Lester, Leslie D. Leve, Yijun Li, Monica McGrath, Xuejuan Ning, Emily Oken, Sharon K. Sagiv, Sheela Sathyanaraya, Frances Tylavsky, Heather E. Volk, Lauren S. Wakschlag, Mingyu Zhang, T. Michael O'Shea, Rashelle J. Musci
Summary: This study examined the association between maternal prenatal smoking and autism spectrum disorder (ASD) in children. The findings suggest a modest association between maternal smoking and ASD diagnosis, as well as an increase in ASD-related traits. However, the study also acknowledges the heterogeneity of results and limitations in data collection and confounders.
Article
Health Care Sciences & Services
Debashree Ray, Alvaro Munoz, Mingyu Zhang, Xiuhong Li, Nilanjan Chatterjee, Lisa P. Jacobson, Bryan Lau
Summary: This study provides a practical method for meta-analyzing cohorts with imbalance in measurement of confounders. The empirical results show that the estimates from this method are closer to the truth and are sensitive to heterogeneity in confounding bias across cohorts.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Pediatrics
Kartikeya Makker, Mingyu Zhang, Guoying Wang, Xiumei Hong, Cuilin Zhang, Xiaobin Wang
Summary: This study aims to investigate the impact of prematurity and other prenatal and perinatal factors on childhood insulin levels. The results showed that preterm infants had higher plasma insulin levels at birth and in early childhood. Factors associated with higher insulin levels in early childhood included insulin levels at birth, race, sex, maternal smoking, maternal perceived stress, in utero drug exposure, maternal pregestational diabetes mellitus, and maternal preconception overweight and obesity.
PEDIATRIC RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Curtis Tilves, Hsin-Chieh Yeh, Nisa Maruthur, Stephen P. Juraschek, Edgar Miller, Karen White, Lawrence J. Appel, Noel T. Mueller
Summary: The levels of butyrate in both serum and feces are associated with lowered blood pressure. Butyrate may serve as a target for interventions aimed at reducing blood pressure.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Peripheral Vascular Disease
Mingyu Zhang, Tammy M. Brady, Jessie P. Buckley, Lawrence J. Appel, Xiumei Hong, Guoying Wang, Liming Liang, Xiaobin Wang, Noel T. Mueller
Summary: This study found that alterations in cord blood metabolome during infancy may be associated with the early life origins of hypertension, particularly related to acylcarnitine and purine metabolism.
Article
Endocrinology & Metabolism
Kartikeya Makker, Mingyu Zhang, Guoying Wang, Xiumei Hong, Khyzer Aziz, Tammy M. Brady, Xiaobin Wang
Summary: This study examined the longitudinal trajectories of leptin and adiponectin from birth to early childhood and their influential factors. It found differences in hormone trajectories and risk factors between preterm and term infants.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Review
Biochemistry & Molecular Biology
Yuanxi Jia, Xuhao Yang, Lisa M. Wilson, Noel T. Mueller, Cynthia L. Sears, Glenn J. Treisman, Karen A. Robinson
Summary: This scoping review mapped the available evidence on the health impact of gut microbiota-derived metabolites. The study identified several metabolites that are associated with hepatobiliary disorders, colorectal cancer, and other digestive disorders. More prospective studies and clinical trials are needed to further understand the associations between metabolites and diseases.
Editorial Material
Peripheral Vascular Disease
Mingyu Zhang, Stephen P. Juraschek
Article
Public, Environmental & Occupational Health
Taylor M. Etzel, Jordan R. Kuiper, Xiaobin Wang, Noel T. Mueller, Antonia M. Calafat, Kim M. Cecil, Aimin Chen, Bruce P. Lanphear, Kimberly Yolton, Heidi J. Kalkwarf, Joseph M. Braun, Jessie P. Buckley
Summary: A prospective study found that early-life phthalate exposures may affect cardiometabolic outcomes during adolescence. The concentrations of nine phthalate metabolites in urine samples collected during pregnancy and childhood were associated with cardiometabolic biomarkers at age 12, with differences observed between males and females.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Elisabeth L. P. Sattler, Oluwabunmi Ogungbe, Amelia S. Wallace, Zahra Aryan, Noelle Castilla-Ojo, Jin Dai, Ileana De Anda-Duran, Kathryn Foti, Charles A. German, Eric T. Hyde, Scott R. Jafarian-Kerman, Karla N. Kendrick, Ben King, Adam Edward Lang, Olive Tang, Ruth-Alma Turkson-Ocran, Luis A. Rodriguez, Frances M. Wang, Mingyu Zhang, Marie-France Hivert, Pamela L. Lutsey
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Meeting Abstract
Peripheral Vascular Disease
Mingyu Zhang, Wei Perng, Sheryl L. Rifas-Shiman, Emily Oken, Marie-France Hivert
Article
Cardiac & Cardiovascular Systems
Mingyu Zhang, Izzuddin M. Aris, Pi-I Debby Lin, Sheryl L. Rifas-Shiman, Tammy M. Brady, Tamarra James-Todd, Emily Oken, Marie-France Hivert
Summary: This study found associations between prenatal and childhood PFAS exposures and blood pressure at specific time points, but no consistent associations across all time points or PFAS types.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Medicine, General & Internal
Lina Feng, Mingyu Zhang, Jialun Guan, Yu Zhang, Yujie Huang, Ruonan Dong, Kai Zhao, Suhong Xia, Fang Xiao, Jiazhi Liao
Summary: A retrospective study found that esophageal/duodenal xanthelasma may not be associated with upper gastrointestinal diseases, but gastric xanthelasma (GX) is related to atrophic gastritis, intestinal metaplasia, gastric cancer, and H.pylori infection, especially multiple GXs which may serve as easily detectable warning signs for these diseases.
FRONTIERS IN MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Jia-Lun Guan, Li-Na Feng, Ying-Ying Han, Su-Hong Xia, Kai Zhao, Ming-Yu Zhang, Yu Zhang, Ruo-Nan Dong, Yu-Jie Huang, Ji-Yan Li, Jia-Zhi Liao, Pei-Yuan Li
Summary: This study provides an overview of clinical trials on Helicobacter pylori eradication and analyzes the global trends and hotspots in this field. The results reveal that bismuth-containing quadruple therapy is the most studied regimen, and clinical trials on potassium-competitive acid blockers-based therapy, probiotics, and high-dose dual therapy are increasing.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2023)