Article
Medicine, Research & Experimental
Noushin Sadat Ahanchi, Seyed Saeed Tamehri Zadeh, Davood Khalili, Fereidoun Azizi, Farzad Hadaegh
Summary: Different trajectories were observed in waist circumference and triglyceride levels between genders. High stable and high-increasing waist circumference trajectories were significantly associated with incident hypertension. For triglyceride levels, decreasing and inverse U-shape trajectories among women were significantly associated with hypertension risk.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Yimin Zhu, Yanling Fu, Minyue Tang, Huanmiao Yan, Fanghong Zhang, Xiaoling Hu, Guofang Feng, Yu Sun, Lanfeng Xing
Summary: This study aims to evaluate the effect of ovarian hyperstimulation syndrome (OHSS) on blood pressure of singletons after in vitro fertilization (IVF).
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Azra Ramezankhani, Fereidoun Azizi, Mitra Hasheminia, Farzad Hadaegh
Summary: This study examined the association between obesity indices and hospitalization rates in Iranian adults. Obese individuals and those with high waist circumference had higher rates of hospitalization, particularly in women, suggesting that obesity prevention programs may reduce hospitalizations.
Article
Public, Environmental & Occupational Health
Haruko Ono, Kotomi Akahoshi, Michiaki Kai
Summary: Regardless of lifestyle, both men and women showed an increase in waist circumference over a 10-year period, with women experiencing a decrease in body weight but an increase in waist circumference. This increase in waist circumference also worsened lipid metabolism, as evidenced by changes in triglyceride and lipoprotein levels. Therefore, monitoring waist circumference may be more important than body weight or BMI for middle-aged and elderly individuals for effective health checkups.
ARCHIVES OF PUBLIC HEALTH
(2022)
Article
Psychology, Applied
Sanne J. W. Hoepel, Isabel K. Schuurmans, Charlotte A. M. Cecil, Vincent W. V. Jaddoe, Annemarie I. Luik
Summary: Exposure to specific stressors has been found to associate with higher adiposity in adulthood. This study assesses the association between overlapping effects of stress domains, including parenting-related stress, and subsequent adiposity in mothers. The results indicate that greater life stress over the course of 10 years is associated with a higher BMI and larger waist circumference in mothers.
Article
Genetics & Heredity
Bastien Ducreux, Jean Frappier, Celine Bruno, Abiba Doukani, Magali Guilleman, Emmanuel Simon, Aurelie Martinaud, Deborah Bourc'his, Julie Barberet, Patricia Fauque
Summary: This study investigated the DNA methylation profiles of 7-8-year-old children conceived through assisted reproductive technology (ART) or naturally, and found that ART-conceived children displayed limited genome-wide DNA methylation variation compared to naturally conceived children. The mode of conception did not significantly affect DNA methylation differences in childhood.
Article
Pediatrics
Omneya Magdy Omar, Mohamed Naguib Massoud, Afaf Gaber Ibrahim, Nada Atef Khalaf
Summary: This study explores the relationship between early feeding practices, eating behavior, and body composition among primary school children. The results show that children with obesity and overweight have higher scores in food approach subscales and lower scores in food avoidance subscales. The conclusion highlights the importance of early feeding practices and eating behavior as preventive approaches for obesity.
WORLD JOURNAL OF PEDIATRICS
(2022)
Article
Obstetrics & Gynecology
Iris G. Insogna, Andrea Lanes, Elizabeth S. Ginsburg, Catherine Racowsky
Summary: The refreshment of medium on day 6 did not increase the proportion of usable embryos on day 7 overall, with an adverse effect seen in women aged 40 and above. Extending the culture of embryos to day 7 resulted in additional blastocysts available for clinical use.
HUMAN REPRODUCTION
(2021)
Article
Nutrition & Dietetics
Teresa G. Castro, Sarah Gerritsen, Juliana A. Teixeira, Avinesh Pillai, Dirce Maria L. Marchioni, Cameron C. Grant, Susan M. B. Morton, Clare R. Wall
Summary: This study used a nationally generalisable birth cohort data to investigate the adherence to dietary guidelines among infants, and found that most infants did not meet the national Infant Feeding Guidelines. Maternal characteristics were found to have strong associations with children's overweight/obesity/central adiposity, confirming the construct validity of the Infant Feeding Index.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Fatemeh Vazirian, Susan Darroudi, Hamid Reza Rahimi, Mohamadreza Latifi, Behrouz Shakeri, Samaneh Abolbashari, Amir Hooshang Mohammadpour, Habibollah Esmaily, Mohsen Mouhebati, Sara Samadi, Majid Ghayour Mobarhan
Summary: Non-high-density lipoprotein-cholesterol (non-HDL-C) and increased waist circumference serve as significant predictors of metabolic syndrome (MetS) in the Iranian population.
LIPIDS IN HEALTH AND DISEASE
(2023)
Article
Multidisciplinary Sciences
Dongyang Wang, Zhenghao Zhao, Xia Xue, Juanzi Shi, Wenhao Shi
Summary: This study investigated the potential of glycan profile in spent blastocyst culture medium as a biomarker for predicting implantation outcome. It was found that the binding signals of 10 lectins were different between successful and failed implantation samples, with increased glycan binding to lectins NPA, UEA-I, MAL-I, LCA and GNA, and decreased binding to lectins DBA and BPL in successful implantation. The glycan profile in spent culture medium showed no significant differences in embryos with different morphological grades except for the binding of UEA-I between Poor and Medium blastocysts. Therefore, detection of glycan profile in spent culture medium may provide a non-invasive assessment assay of embryo viability and contribute to understanding molecular mechanisms in embryo implantation.
Article
Pharmacology & Pharmacy
C. C. Vaduva, R. M. Cilica, A. Nastase, A. Carp-Veliscu, B. Doroftei
Summary: This case report demonstrates a successful pregnancy after IVF culture medium was contaminated with E. coli. By utilizing specific laboratory methods to remove the contamination, a healthy baby was obtained.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Joshua Stokar, Tair Ben-Porat, Donia Kaluti, Mahmud Abu-Gazala, Ram Weiss, Yoav Mintz, Ram Elazari, Auryan Szalat
Summary: In this longitudinal cohort study, the researchers found that sleeve gastrectomy can lead to changes in bone mineral density (BMD) and trabecular bone score (TBS), indicating potential negative effects on bone health.
Article
Clinical Neurology
Nicolaj J. Holm, Randi Steensgaard, Lone H. Schou, Tom Moller, Helge Kasch, Fin Biering-Sorensen
Summary: The study found that overall BMI remained stable but higher than recommended in people with SCI undergoing rehabilitation at two national centers in Denmark. Participants with AIS D SCI had significantly higher BMI during rehabilitation compared to other groups, and their BMI increased from discharge to follow-up.
Article
Obstetrics & Gynecology
Linette van Duijn, Regine P. M. Steegers-Theunissen, Esther B. Baart, S. P. Willemsen, Joop S. E. Laven, Melek Rousian
Summary: This study demonstrates that the SAGE 1-Step culture medium accelerates embryonic growth trajectories compared to Vitrolife G-1 PLUS and naturally conceived pregnancies, particularly in male embryos. Further research should focus on the impact of culture media on postnatal development and susceptibility to non-communicable diseases.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Review
Environmental Sciences
Lucas Panneel, Govindan Malarvannan, Philippe G. Jorens, Adrian Covaci, Antonius Mulder
Summary: This review provides a comprehensive overview of DEHP and alternative plasticizers in neonatal intensive care units, highlighting health risks and the need for further research. Despite efforts by toxicologists and regulators, awareness of the issue remains insufficient among healthcare professionals.
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Letter
Obstetrics & Gynecology
Marleen M. H. J. van Gelder, Hubertina C. J. Scheepers, Luc J. M. Smits
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Food Science & Technology
Rima Obeid, Simone J. P. M. Eussen, Monique Mommers, Luc Smits, Carel Thijs
Summary: The study found that an imbalance in maternal intake of folate and B12 during pregnancy does not affect birthweight, but may impact the weight z score of infants at 1-2 years old. Low maternal dietary B12 intake and elevated methylmalonic acid levels are associated with higher birthweight, suggesting a potential risk for later obesity in infants.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Multidisciplinary Sciences
Daniek A. M. Meijs, Bas C. T. van Bussel, Bjorn Stessel, Jannet Mehagnoul-Schipper, Anisa Hana, Clarissa I. E. Scheeren, Sanne A. E. Peters, Walther N. K. A. van Mook, Iwan C. C. van der Horst, Gernot Marx, Dieter Mesotten, Chahinda Ghossein-Doha, Nanon F. L. Heijnen, Johannes Bickenbach, Meta C. E. van der Woude, Anne Raafs, Sander M. J. van Kuijk, Luc J. M. Smits, Emma B. N. J. Janssen, Noella Pierlet, Ben Goethuys, Jonas Bruggen, Gilles Vermeiren, Hendrik Vervloessem, Mark M. G. Mulder, Marcel Koelmann, Julia L. M. Bels, Laura Bormans-Russell, Micheline C. D. M. Florack, Willem Boer, Margot Vander Laenen
Summary: This study found that female patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had higher survival rates in intensive care units (ICUs) compared to male patients, regardless of age, disease severity, smoking, obesity, comorbidities, anti-infection/inflammatory therapy, and country.
SCIENTIFIC REPORTS
(2022)
Article
Psychology, Clinical
Karina Chaibekava, Amber Scheenen, Adrie Lettink, Luc Smits, Josje Langenveld, Rafli van de Laar, Babette Peeters, Sanne Joosten, Marie-Louise Verstappen, Marianne Nieuwenhuijze, Hubertina Scheepers
Summary: Giving birth during the COVID-19 pandemic does not decrease women's sense of control. Factors associated with women's sense of control during birth include Dutch ethnic background, antenatal worry, antenatal anxiety, and the use of analgesics during birth.
JOURNAL OF PSYCHOSOMATIC OBSTETRICS & GYNECOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Haoyi Wang, Luc Smits, Polina Putrik
Summary: The aim of this study was to provide small area estimations (SAE) of smoking prevalence during pregnancy in South Limburg, the Netherlands. The results revealed a heterogeneous prevalence of smoking, which was associated with a higher proportion of non-western migrants and lower average income. These estimates are important for informing local prevention policies and providing a methodological example for public health researchers on the application of Bayesian methods for SAE.
SPATIAL AND SPATIO-TEMPORAL EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Jessica P. M. M. Willemse, Luc J. M. Smits, Mandy M. E. Braat, Linda J. E. Meertens, Pim van Montfort, Martien C. van Dongen, Jonas Ellerbrock, Ivo M. A. van Dooren, Ella J. Duvekot, Iris M. Zwaan, Marc E. A. Spaanderman, Hubertina C. J. Scheepers
Summary: Incorporating calcium advice into early pregnancy counseling has been shown to decrease the risk of inadequate calcium intake during pregnancy, but half of women still have inadequate intake. In CAC, an increase in predicted pre-eclampsia risk is associated with a decrease in the risk of inadequate intake, which is a trend reversal compared to RC.
JOURNAL OF PERINATAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Lucas Panneel, Paulien Cleys, Camille Breugelmans, Christina Christia, Govindan Malarvannan, Giulia Poma, Philippe G. Jorens, Antonius Mulder, Adrian Covaci
Summary: We investigated the concentrations of DEHP and alternative plasticizers (APs) to which premature neonates are exposed during parenteral nutrition (PN) therapy. Our results showed that DEHP and several APs are present in medical devices used for neonatal PN administration, with higher concentrations found in lipid emulsions. Premature neonates receiving PN therapy were estimated to be exposed to 13.9 μg/kg/d of DEHP and 95.7 μg/kg/d of ATBC, below their respective reference doses.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Medicine, General & Internal
Tim Hundscheid, Wes Onland, Elisabeth M. W. Kooi, Daniel C. Vijlbrief, Willem B. de Vries, Koen P. Dijkman, Anton H. van Kaam, Eduardo Villamor, Andre A. Kroon, Remco Visser, Susanne M. Mulder-de Tollenaer, Barbara De Bisschop, Peter H. Dijk, Daniela Avino, Catheline Hocq, Alexandra Zecic, Marisse Meeus, Tessa de Baat, Frank Derriks, Tine B. Henriksen, Kasper J. Kyng, Rogier Donders, Debbie H. G. M. Nuytemans, Bart Van Overmeire, Antonius L. Mulder, Willem P. de Boode
Summary: This trial showed that in the treatment of PDA in extremely preterm infants, expectant management was noninferior to early ibuprofen treatment in terms of necrotizing enterocolitis, bronchopulmonary dysplasia, or death at 36 weeks' postmenstrual age.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Pediatrics
Marina-Stefania Stroe, Lieselotte Van Bockstal, Allan Valenzuela, Miriam Ayuso, Karen Leys, Pieter Annaert, Sebastien Carpentier, Anne Smits, Karel Allegaert, Adrian Zeltner, Antonius Mulder, Chris Van Ginneken, Steven Van Cruchten
Summary: Animal models provide valuable information on human disease mechanisms and (patho)physiological factors affecting drug development. Nonclinical data is critical for understanding pediatric disease conditions and developing new drug therapies. This study aimed to develop a neonatal Gottingen Minipig model for investigating the impact of systemic hypoxia and therapeutic hypothermia on drug disposition in perinatal asphyxia.
FRONTIERS IN PEDIATRICS
(2023)
Article
Environmental Sciences
Paulien Cleys, Lucas Panneel, Jasper Bombeke, Catalina Dumitrascu, Govindan Malarvannan, Giulia Poma, Antonius Mulder, Philippe G. Jorens, Adrian Covaci
Summary: This study reports metabolites of phthalate and alternative plasticizers in neonatal hair samples as biomarkers for exposure to these plasticizers. Results showed that hair sampled from premature neonates after a NICU stay contained significantly higher metabolite concentrations of both phthalates and alternative plasticizers compared to healthy control neonates. Prolonged NICU exposure to respiratory support devices and gastric tubes was correlated with increased concentrations in hair samples.
ENVIRONMENTAL RESEARCH
(2023)
Article
Medicine, Research & Experimental
Pim B. B. Schol, Natascha de Lange, Yvonne Henskens, Luc J. M. Smits, Nicol A. C. Smeets, Hubertina C. J. Scheepers
Summary: This study aimed to evaluate the effect of fluid management on coagulation parameters in early postpartum hemorrhage (PPH). In a multicenter, randomized trial, women with 500 mL of blood loss in the third stage of labor were randomized to receive a restrictive or liberal fluid administration strategy. The results showed that there was no clinically relevant effect of fluid management on thromboelastometric hemostatic and regular coagulation parameters in women with PPH <1500 mL.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2023)
Article
Medicine, General & Internal
Thais Rocha, John Allotey, Alfredo Palacios, Joshua Peter Vogel, Luc Smits, Guillermo Carroli, Hema Mistry, Taryn Young, Zahida P. Qureshi, Gabriela Cormick, Kym I. E. Snell, Edgardo Abalos, Juan-Pablo Pena-Rosas, Khalid Saeed Khan, Koiwah Koi Larbi, Anna Thorson, Mandisa Singata-Madliki, George Justus Hofmeyr, Meghan Bohren, Richard Riley, Ana Pilar Betran, Shakila Thangaratinam
Summary: Low dietary calcium intake is a risk factor for pre-eclampsia. Calcium supplementation can prevent pre-eclampsia in women with low dietary calcium. This study aims to determine the optimal dose and timing of calcium supplementation and evaluate its cost-effectiveness in preventing pre-eclampsia.
Article
Obstetrics & Gynecology
Karina Chaibekava, Amber J. C. Scheenen, Adrie Lettink, Luc J. M. Smits, Josje Langenveld, Rafli Van De Laar, Babette Peeters, Sanne Joosten, Marie-Louise Verstappen, Carmen D. Dirksen, Marianne J. Nieuwenhuijze, Hubertina C. J. Scheepers
Summary: Continuous care provided by maternity care assistants during labor can reduce the use of epidural analgesia and peripartum costs, but implementation needs to be addressed.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Lynn T. M. Strijbos, Manouk L. E. Hendrix, Salwan Al-Nasiry, Luc J. M. Smits, Hubertina C. J. Scheepers
Summary: This study assessed the costs and benefits of different first-trimester preeclampsia risk estimation algorithms coupled with low-dose aspirin treatment. The EXPECT and Fetal Medicine Foundation models showed similar effectiveness in preventing preeclampsia, while the National Institute for Health and Care Excellence model and no risk assessment were inferior. The EXPECT model resulted in the highest cost savings, but also required the highest number of women to be treated with aspirin.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)