期刊
HIV CLINICAL TRIALS
卷 19, 期 3, 页码 112-119出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/15284336.2018.1461999
关键词
human immunodeficiency virus; community health workers; retention in care; rural care; community randomized trials; Ethiopia; sub-Saharan Africa
资金
- National Institute of Mental Health, National Institutes of Health [5R01MH105290]
Background: Although HIV therapy is delivered to millions globally, treatment default (especially soon after entering care) remains a challenge. Community health workers (CHWs) can provide many services for people with HIV, including in rural and resource-limited settings. Objectives: We designed and implemented a 32 site community randomized trial throughout southern Ethiopia to assess an intervention using CHWs to improve retention in HIV care. Methods: Sixteen district hospital and 16 local health center HIV clinics were randomized 1:1 to be intervention or control sites. From each site, we enrolled adults newly entering HIV care. Participants at intervention sites were assigned a CHW who provided: HIV and health education; counseling and social support; and facilitated communication with HIV clinics. All participants are followed through three years with annual health surveys, plus HIV clinic record abstraction including clinic visit dates. CHWs record operational data about their client contacts. Results: 1799 HIV patients meeting inclusion criteria were enrolled and randomized: 59% were female, median age = 32years, median CD4 + count = 263 cells/mm(3), and 41% were WHO Stage III or IV. A major enrollment challenge was fewer new HIV patients initiating care at participating sites due to shortage of HIV test kits. At intervention sites, 71 CHWs were hired, trained and assigned to clients. In meeting with clients, CHWs needed to accommodate to various challenges, including HIV stigma, distance, and clients lacking cell phones. Conclusions: This randomized community HIV trial using CHWs in a resource-limited setting was successfully launched, but required flexibility to adapt to unforeseen challenges.
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