Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease

Progression and Natural History of Nonalcoholic Fatty Liver Disease in Adults

(2016) Andrea Marengo et al.   Clinics in Liver Disease

Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease

(2016) Quentin M. Anstee et al.   GASTROENTEROLOGY

Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study

(2016) Jeffrey Cui et al.   HEPATOLOGY

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

(2016) Lucie Popineau et al.   MOLECULAR AND CELLULAR BIOLOGY

A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy

(2016) Damien Galant et al.   Cells

Exome Sequencing Identifies a Novel LMNA Splice-Site Mutation and Multigenic Heterozygosity of Potential Modifiers in a Family with Sick Sinus Syndrome, Dilated Cardiomyopathy, and Sudden Cardiac Death

(2016) Michael V. Zaragoza et al.   PLoS One

Diagnostic Performance of Magnetic Resonance Elastography in Staging Liver Fibrosis: A Systematic Review and Meta-analysis of Individual Participant Data

(2015) Siddharth Singh et al.   Clinical Gastroenterology and Hepatology

Networking in the nucleus: a spotlight on LEM-domain proteins

(2015) Lacy J Barton et al.   CURRENT OPINION IN CELL BIOLOGY

Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study

(2015) Rohit Loomba et al.   GASTROENTEROLOGY

Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States

(2015) Robert J. Wong et al.   GASTROENTEROLOGY

Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins

(2015) Sandra Vidak et al.   GENES & DEVELOPMENT

Serum microRNAs explain discordance of non-alcoholic fatty liver disease in monozygotic and dizygotic twins: a prospective study

(2015) Amir Zarrinpar et al.   GUT

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Nuclear envelope-related lipodystrophies

(2014) A.C. Guénantin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Non-alcoholic fatty liver disease

(2014) N. Sattar et al.   BMJ-British Medical Journal

dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations

(2013) Xiaoming Liu et al.   HUMAN MUTATION

Lamin aggregation is an early sensor of porphyria-induced liver injury

(2013) A. Singla et al.   JOURNAL OF CELL SCIENCE

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease

(2013) Kevin Gesson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Broken nuclei – lamins, nuclear mechanics, and disease

(2013) Patricia M. Davidson et al.   TRENDS IN CELL BIOLOGY

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

A Chinese patient with acquired partial lipodystrophy caused by a novel mutation with LMNB2 gene

(2012) Jinzhi Gao et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

The nuclear lamins: flexibility in function

(2012) Brian Burke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear lamin functions and disease

(2012) Veronika Butin-Israeli et al.   TRENDS IN GENETICS

Are B-type lamins essential in all mammalian cells?

(2012) Shao H. Yang et al.   Nucleus

Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation

(2011) Vanja Pekovic et al.   AGING CELL

High prevalence of laminopathies among patients with metabolic syndrome

(2011) Anne Dutour et al.   HUMAN MOLECULAR GENETICS

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

PNPLA3variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

(2010) Elizabeth K. Speliotes et al.   HEPATOLOGY

Quantification of Liver Fat with Magnetic Resonance Imaging

(2010) Scott B. Reeder et al.   Magnetic Resonance Imaging Clinics of North America

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

(2010) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Laminopathies and the long strange trip from basic cell biology to therapy

(2009) Howard J. Worman et al.   JOURNAL OF CLINICAL INVESTIGATION

“IF-pathies”: a broad spectrum of intermediate filament–associated diseases

(2009) M. Bishr Omary   JOURNAL OF CLINICAL INVESTIGATION

Loss of nucleoplasmic LAP2α–lamin A complexes causes erythroid and epidermal progenitor hyperproliferation

(2008) Nana Naetar et al.   NATURE CELL BIOLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS