Myeloid Notch1 deficiency activates the RhoA/ROCK pathway and aggravates hepatocellular damage in mouse ischemic livers

Phosphatase and tensin homolog-β-catenin signaling modulates regulatory T cells and inflammatory responses in mouse liver ischemia/reperfusion injury

(2017) Qiang Zhu et al.   LIVER TRANSPLANTATION

The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury

(2016) Shi Yue et al.   HEPATOLOGY

The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation

(2016) Yingli Shang et al.   NATURE IMMUNOLOGY

Innate Immune Regulations and Liver Ischemia-Reperfusion Injury

(2016) Ling Lu et al.   TRANSPLANTATION

Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury

(2015) Hai Huang et al.   HEPATOLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

(2013) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles

(2013) Shann S. Yu et al.   MOLECULAR PHARMACEUTICS

β-catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury

(2012) Bibo Ke et al.   HEPATOLOGY

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

Current strategies to minimize hepatic ischemia–reperfusion injury by targeting reactive oxygen species

(2012) Hartmut Jaeschke et al.   Transplantation Reviews

Functional Role of Monocytes and Macrophages for the Inflammatory Response in Acute Liver Injury

(2012) Henning W. Zimmermann et al.   Frontiers in Physiology

Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling

(2011) Heng-Chao Yu et al.   HEPATOLOGY

Notch Signal Suppresses Toll-like Receptor-triggered Inflammatory Responses in Macrophages by Inhibiting Extracellular Signal-regulated Kinase 1/2-mediated Nuclear Factor κB Activation

(2011) Qinghua Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HO-1–STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling

(2011) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Rho inhibitor prevents ischemia–reperfusion injury in rat steatotic liver

(2011) Shintaro Kuroda et al.   JOURNAL OF HEPATOLOGY

Notch Signaling in the Immune System

(2010) Freddy Radtke et al.   IMMUNITY

Myeloid PTEN Promotes Inflammation but Impairs Bactericidal Activities during Murine Pneumococcal Pneumonia

(2010) G. Schabbauer et al.   JOURNAL OF IMMUNOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

(2009) B. Spee et al.   GUT

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

(2009) P. Y. Mong et al.   JOURNAL OF IMMUNOLOGY

Adoptive Transfer of Ex Vivo HO-1 Modified Bone Marrow–derived Macrophages Prevents Liver Ischemia and Reperfusion Injury

(2009) Bibo Ke et al.   MOLECULAR THERAPY

Inhibition of Kupffer cell-mediated early proinflammatory response with carbon monoxide in transplant-induced hepatic ischemia/reperfusion injury in rats

(2008) Koji Tomiyama et al.   HEPATOLOGY

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways

(2008) Xiaoyu Hu et al.   IMMUNITY

Notch signaling is activated by TLR stimulation and regulates macrophage functions

(2007) Tanapat Palaga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY